Starting Zytiga today. For those who are using it, do you find it better to take on an empty stomach in the morning or before bed? Also, do you take Prednisone at the same time or a different time of the day? I'm taking 1,000MG per day, 4 pills! Seems like a lot. is this typical?
Diagnosed July 2016-Stage 4, 4 bone mets, Lupron and Xgeva immediately, chemo in winter of 2016, provenge spring 2017. PSA from 0 to 20 since chemo.
Thanks!
I take Zytiga before bed. Since it has to be on an empty stomach, I also cut out any late night snacks...
I take prednisone with breakfast. I find that if I take it later, it can make it harder for me to go to sleep. And it helps my energy level during the day.
Best of luck with it! I’ve had an undetectable PSA for 4-months since I started taking it. Hope your results are equally good! 😊
Best,
James
Thanks!
I am also on 4 pills of Zytiga and prednisone. I usually wake up early (5:30) to go swimming and that’s when I take it. I take the prednisone about two hours later, after my workout and breakfast.
Thanks!
I take both first thing in the morning on an empty stomach.
I take my Prednisone in the morning with coffee and something small to eat for breakfast as I'm rushing off to work. I bring a small empty old prescription bottle to which I add my 4 Zytiga pills to work with me. I rarely if ever eat lunch so take the Zytiga in mid afternoon.
I am taking zytiga in empty stomach and have my breakfast after one hour. I take prednisone with breakfast. So far it works well for me.
I take the prednisone with breakfast and the Zytiga at bedtime. That cuts down on TV snacking; which is a good thing.
I've had no side effects and best of all - it works!
Good luck!
G'Day Ewhite
My oncologist suggested I set my alarm for 6am, take the 4 pills, then snooze for an hour or so before breakfast. That's when I take the prednisolone, as well as some supplements, such as magnesium(to help with hot flushes and calcium uptake) as well as vitamin D3/K2, calcium and curcumin. I also drink camomile tea. I don't know (or care) which one is helping, but I have very few hot flushes any more. I am also on Triptorelin 6 monthly implants.
Stay strong and positive, it's a long road we are on!!
Cheers
Thevvy
I talked my Prednisone first thing when I get up. Sleep issues from it anyway. 8 have found afternoon is best a few hours after lunch for my four pills of Zitiga works best for me. I have an alarm set on my clock to remind me at 3:30pm.
I take my hand full of pills when I get up. The bottle says take the prednisone 2 times a day but that effected my sleep so all at once it is.
I take mine at 6 AM on an empty stomach with a whole bottle of spring water make sure you drink plenty of water with it surly helps a great deal. My prednisone is taken a few hours later with breakfast then again with diner.
Welcome to the to the APC Brotherhood. Remember staying positive and educating yourself is the best way to fight this . Leo
I take my Zytiga 1000mg every morning at 5:30am. Then I take 1 prednisone at 6:30 with my multivitamin when I eat breakfast. I then take my 2nd prednisone at 1:30pm just before my radiation treatment at 1:50pm.
I’ve been on this regime for 6.5 years. I take my Prednisone with Lansaprozole and blood pressure (Amias) tablets at 9 a.m. with or just after breakfast. Zytiga at 11.00 am, then lunch sometime after 12. Alarm on my phone is set to 11am every day as a reminder. Regular as clockwork, just holidays in different time zones screw things up, when I take drugs earlier rather than later.
I take Prednisone at night after dinner (no sleep issues yet), and Zytiga between 1am-3am depending on when I get up to use the bathroom. 1000mg dose should be on empty stomach.
Timely post, Ewhite99,
After one week, there have been no adverse side effects of either drug. Some improvements are clearly due to inguinal hernia surgery healing. No additional opioids have been taken and only one ibuprofen.
Schedule: Black coffee and a piece of toast with peanut butter and fruit spread, usually between 5 and 6 a.m. 2 AA (that’s what is inscribed on the tablet) and 1 Prednisone (too tiny to inscribe) at 7 a.m. Light supper at 5-6 p.m. 2 Zytiga and 1 Prednisone at 7 p.m.
Nighttime restlessness is considerably less. Bowel blockage is improving.
The last couple months have been ones of the most severe pain since diagnosis, primarily bone pain in random locations but mostly in lower left back and hip. Much groaning and moaning and trying to find a tolerable position. Walking slowly, stooped, and grasping back, i.e. it has been a long three weeks waiting for an Xgeva injection. We hope prior authorization has been achieved and that there will be no further delays after his next appointment on June 4th. I’ll update you on Xgeva later in June. $$$$
On other fronts there is no garden for the first time in decades. Mrs. S is mowing the near- acre. Mr. S has inclinations to do many things but then lacks the energy to do them and suffers too much bone pain to persist.
Family has returned from wintering in the south and is visiting. One came bearing many gifts of food. Another brought cookies and ice cream, repaired the basement sink plumbing, and was honest about our remaining time. Leswell said, “I don’t know what’s next for me.” Reply was that he had to be honest, there wasn’t a lot of time left, and he hoped my husband enjoyed the days and didn’t have too painful a conclusion. (That’s approximate.) Both love and admire Leswell a lot but face his limited future in different ways. As for his spouse, I can’t imagine my life without a never-ending sensation of shock, disbelief, and fear. The moment of dx is searing, psychic trauma. My father’s clock ticks the annoying warning. “Time is fleeting. Do something now. Read Health Unlocked!” Seriously, HU has been such a help, both the persons who stick to facts, abstracts, etc. and those who write in personal, diary fashion. Thanks to both.
P.S. Not recommending lowering the dosage except if one wishes to spend less, but check out the following if you have nothing but time. Go well everyone.
P.S. I do know it’s Abiraterone Acetate. We love E B White!
Question about timing Zytiga dosage
Are we jumping the gun here, can we see if Zytiga settles my PSA first before hitting me with Chemo Again?
Zytiga advise on best time to take. 
