Dietary calcium intake and rate of bone loss in men.

[pjoshea13]

Newish study below.

The PCa literature suggests that high calcium intake (from dairy &/or supplements) increases the risk for aggressive PCa.

Any yet men with fear of osteoporosis might feel they have no choice.

It has always seemed odd to me that calcium would be thought of as the solution to bone loss. As though topping up a bucket would take care of the hole in the bottom. Vitamin K deficiency is common in the U.S., & K is essential for calcium transport to bone. Without K (preferrably K2-M7), we are likely to have calcium deposited on arterial walls.

In the new study:

"Dietary Ca {calcium} intake ... was not associated with the markers of bone turnover. BMD {bone mineral density} and rates of bone loss were unrelated to Ca intake in these men. This suggests that strategies to increase Ca intake are unlikely to impact on the prevalence of and morbidity from male osteoporosis."

See my posts:

Foods/Supplements-Vitamins: Vitamin K

“During a mean follow-up time of 8.6 years, 268 incident cases of prostate cancer, including 113 advanced cases, were identified. We observed a nonsignificant inverse association between total prostate cancer and total menaquinone intake"

“The association was stronger for advanced prostate cancer"

Foods/Supplements-Vitamins: Calcium

"Higher calcium intake ... was associated with a higher risk of

advanced and fatal prostate cancer

Foods/Supplements-Vitamins: Magnesium

"Serum Mg levels were significantly lower, while the Ca/Mg ratio was

significantly higher, among high-grade cases vs. controls"

-Patrick

ncbi.nlm.nih.gov/pubmed/286...

Br J Nutr. 2017 May;117(10):1432-1438. doi: 10.1017/S0007114517001301. Epub 2017 Jun 13.

Dietary calcium intake and rate of bone loss in men.

Bristow SM1, Gamble GD1, Horne AM1, Reid IR1.

Author information

Abstract

A high Ca intake has been recommended for osteoporosis prevention; however, little research has examined the relationship between dietary Ca and bone health in men. We examined associations between dietary Ca intake, bone mineral density (BMD) and change in BMD at the total body, hip and spine over 2 years in a cohort of men (mean age 57 years, BMI 26 kg/m2) from a trial. Data from the total cohort (n 323) were used in the analysis of Ca intake and BMD at baseline, and data from the placebo group (n 99) were used in the longitudinal analysis of Ca intake and change in BMD. Parathyroid hormone (PTH) and the markers of bone turnover serum total alkaline phosphatase activity, serum C-telopeptide and serum procollagen type-1 N-terminal propeptide were measured in a subset of participants at baseline (n 150), and associations with dietary Ca at baseline were examined. Mean Ca intake was 870 mg/d. Baseline BMD was not related to dietary Ca intake at any site, before or after adjustment for covariables. Similarly, bone loss over 2 years was not related to Ca intake at any site, before or after adjustment. Dietary Ca intake was inversely correlated with PTH at baseline (r -0·19, P=0·02), but was not associated with the markers of bone turnover. BMD and rates of bone loss were unrelated to Ca intake in these men. This suggests that strategies to increase Ca intake are unlikely to impact on the prevalence of and morbidity from male osteoporosis.

KEYWORDS:

25(OH)D 25-hydroxyvitamin D; BMD bone mineral density; PINP procollagen type-1 N-terminal propeptide; PTH parathyroid hormone; Bone density; Cross-sectional studies; Dietary calcium; Osteoporosis; Prospective studies

PMID: 28606219 DOI: 10.1017/S0007114517001301