Metformin & Xtandi Resistance.
New study below. " Although the newly developed second-generation anti-androgen drug enzalutamide can repress prostate cancer progression sig...
Testosterone inhibits the growth of PCa (in mice).
New study below. The BAT concept is that supraphisiological testosterone [ T ] is required for therapeutic effect....
Patrick, Gusgold, et al. Looking back at some unfinished research--that never went further....
Quercetin & AR-V7.
New study below [ 1 ]. A common form of resistance to Xtandi & Zytiga is the emergence of androgen receptor [ AR ] splice variant AR-V7, whic...
Doxycycline down-regulates matrix metalloproteinase expression and inhibits NF-κB signaling
New study below [ 1 ]. " Doxycycline, a synthetic tetracycline ......
Prostate Cancer & Hormones - Insulin-like growth factor [IGF] axis.
Apologies for the length of this post. Some bits will be easy - skip the rest....
"Inflammation.  How to Change the Numbers"
This is my final post on inflammation. Earlier posts: " Inflammation....
Foods/Supplements-Vitamins: Cruciferous Phytochemicals -  Sulforaphane
This is the 5th & final installment on cruciferous vegetable phytochemicals. The best source of sulforaphane is broccoli sprouts [ 1 ]....
Tetracycline / doxycycline / minocycline
This post is prompted by Ed Miller's: " Ten days of the antibiotic clendamycin lowered my PSA for 3 months. " I remembered seeing some PCa-te...
Foods/Supplements-Vitamins: Cruciferous Phytochemicals -  3,3'-Diindolylmethane [DIM]
DIM ( 3,3'-Diindolylmethane ) is thought to be the most important phytochemical found in broccoli. [ 1 ] Estrogen Metabolism....
Prostate Cancer & Hormones - Prolactin
Evolution has given hormones promiscuous roles in the body. A particular hormone may be involved in a number of unrelated functions....
Foods/Supplements-Vitamins: Neem leaf (from Azadirachta indica)
RJ-MN requested this one. [ 1 ] " Azadirachta indica, also known as Neem, Nimtree, and Indian Lilac is a tree in the mahogany family Meliacea...
Foods/Supplements-Vitamins: Magnolia - magnolol - honokiol - obovatol - Relora
Timing of this post is due to Gus, who recently posted enthusiastically about honokiol & time to Lupron failure. [ 1 ] The following deals wi...
Foods/Supplements-Vitamins: Cruciferous Phytochemicals -  Phenethyl isothiocyanate [PEITC]
PEITC is a lesser-known cruciferus phytochemical than DIM or sulforaphane, but there heave been a substantial number of PCa studies. The very...
New full-text review of the AR-V7 problem below [ 1 ]. Not for everyone - TMI?...
Continuing my alphabetic tour, I arrive at coffee, one of the enduring pleasures in life. At last - an easy subject!...
Foods/Supplements-Vitamins: Capsaicin - Cayenne
The active ingredient in cayenne peppers ( hot chilli peppers - Capsicum annuum ) is capsaicin. Capsaicin, oddly, has a chemical structure si...
A PCa study involving apigenin has been appearing roughly every 2 months this past 18 years. A bit frustrating, since while apigenin is found...
Foods/Supplements-Vitamins: Arachidonic acid [AA]
So much for my alphabetic tour - I am back at the letter " A ". Arachidonic acid [ AA ] is an omega-6 fatty acid....
Cannibis cure or hoax, ?
There’s still a lot of confusion across the nation about whether or not marijuana is effective for cancer patients. Odds are you’ve heard som...
Be the first to reply
Start a Community