After five months on 20mg of methotrexate, I am finding my response is getting worse not better.
I take it on monday evening, and when I first started I just had to 'rub out' Tuesday mornings. Now I feel wonky through Monday (presumably because my body has run out and needs more?) into Tuesday, and increasingly into Wednesday as well. I wondered whether it would even things out more if I took two doses of 10 mg instead?
I see the rheumatology consultant again this Friday, and would like to have some extra information before I see him. so if anyone can share their experience, that would help.
Also, I talked to his nurse practitioner a couple of weeks ago about my constantly weeping eyes and general shakiness - especially my shaky hands. She did not think any of this was to do with the methotrexate or prednisone. My GP has given me eye drops and antihistamine, but not much difference.