New research into T Cell involvement in autoimmune diseases

[RichardE]

Stolen from Barnclown's post over on the Lupus group

This looks like an interesting line of research given that I think T Cells are involved in a few types of vasculitis :

cam.ac.uk/research/news/too...

[nicholls]

Thanks found this really interesting especially as I am having Campath asa treatment.

[RichardE Volunteer in reply to nicholls]

I don't know much about campath / alemtuzumab, so I'll have to take a look on google But I have heard of a few folk being given it for Behcets, I understand that there's T cell involvement in giant cell vasculitis and I think it can be used for ANCA vasculitis too.

[michichgo]

Mucho thanks for the post.

Pesky cd8 t cells - they just don't listen.

There are also studies regarding b cell proliferation in vasculitis. Some folks on the vasci foundation forum on Facebook are tested for cd19 & cd20 markers on b cells. Apparently those markers are a precursor to ANCA numbers rising.

I've requested such testing from my nephrologist but thus far, no such luck.

I'm a two-year MPAer.

[Suzym2u Moderator Vasculitis UK]

I believe that Campath is being tried on other types of vasculitis eg:- CSS (EGPA) as part of Clinical trials at the moment.