Does any body get the following side effects from Cellcept and prednisolone

[molliecatone]

I am getting hot flushes though this maybe a coincidence as I am a 47 year old female!!! I am also getting minor shakes mainly in the hands any advice please

[mickt]

Hi im on 25mg pred and get the tremors with it been on it over 6 mths now,ive developed the buffalo hump the treble chin and a fat gut with them.Its an synthetic steroid so rebistributes fat into the areas ive said .Hope it doesn't turn you into a weeble like me .Got to keep your sense of humour.Im presuming you have vasculitis ?.ive large vessel vasc click on my name to see my history too much to write out again...lol..Best of luck to you .

[molliecatone in reply to mickt]

yes I have vasculitis in both eyes no cause has been identified as yet though they are testing me for an auto immune disease called Sarcoidosis.

I also have uveitis both anterior and posterior in both eyes.

[tracynoe]

Currently having terrible night sweats and got the tremors again noy sure if it's from disease activity as I am unwell at moment and losing weight again or if its an age thing or drug side effects what ever the reason my GP is worried

[Chris-Bromsgrove]

As you can see from the picture I am not likely to be susceptible hot flushes. However during my active vasculitis (MPA) I suffered severe night sweats which does seem to happen with a lot of vasculitis patients. These sweats gradually started to subside as the prednisolone and cyclophosphamide did their job. As soon as I started on the high dose of prednisolone (75 mg) my hands developed the shakes and I had difficulty signing my name. As the dose was tapered off the shakes gradually subsided. Your problems could well be as a result of the vasculitis and the prednisolone. Since my vasulitis went into remission I have taken Cellcept as a maintenance drug along with a low dose of pred. I have not experienced any sweats or shakes whilst on Cellcept, so hopefully yours will go away in time as the prednisolone dose is reduced and you enter remission. Best wishes Chris

[cambs13]

Hi, also on Cellcept and prednisilone and yes I too get hot flushes, I am 63, so would think my days of age related flushes are over. They don't last long but do get them on a daily basis.

[Wellsie]

I am a 45 year old male, and I experience hot flushes. I am still under active treatment for my vasculitis, which is presently prednisolone, methyl prednisolone and cyclophosphamide. I have no experience of Cellcept.

Like Chris, I still experience some significant night sweats, and I also get periods of extreme flushing in my face too, particularly after my methyl prednsolone infusion.

[molliecatone]

thanks for all the replys they were a real help.

I am so thankful that my GP mentioned this site

Tracy

[Ayla Volunteer]

Yes, to both, though not usre whether the hot flushes are caused by somehing other than the drugs. My bet is they are. Shakes in the hands only occurred while I was on high dose prednisolone (plus cyclophosphamide) and vanished quite quickly once the steroid dose was lowered and the cyclo swopped for CellCept.

[optimist-ok]

Yes, hot flushes all the time! I'm now on 10mg preds & 15mg methotrexate after 2 yrs. Can't have age as a possibility, though, as I'm 72, so it must be medication! I can only deal with this by wearing layers when cold & removing a layer when necessary - hope this helps. I have to say when I feel I'm boiling inside my face actually feels quite cold.

[rrahman]

Hi.

I Have had the shakes on my hand whenI was on a higher dosage of predisnolone...I'm on 10mg now and have been last 5months. Started on 60mg April this year, the shakes went after I was on a stedy 10 and hadn't kept redreducing it every month by 10mg so I think that helped. I also had the hot flushes....and I'm 26yrs of age.

My shakes of the hand stopped for a while transferring to shakes of my feet. Haven't had either for couple months now.

But my hump treble chin lardy behind and round belly still remains alongside my round inflatable balloon cheeks. That said the cheeks and the hump have gone down a LITTLE since dosage has been steady on 10mg.

I've also had 75% loss of hair and HUGE WIDE cushingoid marks which appear as stretch marks but wider n deeper since start of predisnolone.

Although since the steady dosage of predisnolone I have noticed my hair doesn't fall out much. Before even if I stroked my hair With my fingers it'd jut come out in strands!! I presumed thiswas down to the cyclopho. Chemo like therapy.

So the shakes should hopefully go itself as the dosage is lower as the flushes.

But do keep a careful watch if this co incides with u feeling fairly poorly or crap in a blunt term as a guideline of something possibly being the matter.

Look after yourself

R

[Mags88]

Hi mollie.

I started getting hot flushes when I first started the prednisone. To the point were sweat would literally be running from my head and I would feel faint. I also get she shakes in my hands, sometimes it feels like ny whole body is gittering. I don't think they got worse when I was on cellcept but got better as I reduced the steriods. I was down to 20mg but back up to 60 again now and they are back. Thankfully being winter they are not as bad as last time. I found summer pretty much unbearable. Im 25 so isn't my age hope it settles for you soon x

[Lalamum]

Have read this with interest. Hubby has small vessel vasculitis. Has shakes in hand; presistent tremble when holding hands and overall muscle weakness with visible reduction in muscle mass so this thread very useful.

However, he has lost weight and gets so cold! Cant imagine how he will cope come winter!! Pethaps all early days as he always hungry

[Tinabelle]

I too have the hot flashes and I am 47 as well. I had a hysterectomy when I was 29 so I know it's not menopause. They drive me CRAZY! I'm either too hot or too cold. It's so frustrating! I'm not on cell cept any more but I am still on 10mg. Prednisone. Came down from 1000mg. To 60mg then decreased by 10 monthly. I ended up getting osteoporosis and fracturing 4 vertebrae from the high dose steroids! Sooo painful! The steroids have nasty side effects but they save our lives! I used to have the shakes on higher prednisone doses but am okay in that department now. Good luck to you! Be well!

[shakeel1]

Hi I have been on predisolone since last July and I get hot flushes all the time ,I also e muscle weakness especially in legs and arms . Am on Azathioprine as well.but the symptoms come from the steroids .I have told my consultant but he don't seem to bother about it.