I was diagnosed with WG over 14 years ago and for the past 3 years I have been receiving Rituximab every 6 months and it's been my ' wonder drug ' but after my last infusion in June it did not improve my fatigue and joint pains. It appears I have developed antibodies.
I have been informed today by Dr Jayne that he wishes to try 2 doses at 2 weeks interval and bloods to be taken immediately before and after the 2nd dose to check if it's worked before he considers Plasmapheresis. Has anyone else experienced antibodies and then had this regime and was it effective please ?
Jill