Thyroid UK
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Diuretics and Metabolism

I have been on Bendrofluormethiazide (dieretics) for many many years now, too many to work out.

I was beginning to wonder if it was safe to have been on them for so long and have found that certain tests should have been being done while on them to monitor certain level, potassium etc.

However, more interestingly I have just read that they can cause problems with metabolism and insulin resistance. Im beginning to wonder if this is anything to do with the fact that I find it extremely diffcult to lose weight even on diets as I know alot of us do.

Even more of a thought, could this have had anything to do with the thyroid not working properly now even?

Has anyone else got any evidence of this?

2 Replies

Yes, I believe it is. I am not medically qualified but I will give you some links. On Dr Lowe's there are other topics at the top of the page.

Before the TSH was introduced as a diagnosis, doctors were skilled in clinical symptoms and the most dominant was swelling and you would have been given a natural dessicated thyroid hormone.


Hi , Several things spring to mine, it is vital to drink a lot of fluid, lots of water , this enables the diuretics to work better and also protects the kidneys. You should have U`s and E`s ( kidney function blood ) at least yearly, if not stable, more. Potassium is lethal if too high or too low, it is an electrolyte, sodium ( also U`s and E`s) must be in range. Sodium does deplete with too much fluid. Both of these are electrolytes and need to be watched and kept in range, also calcium and magnesium. Calcium can be effected especially ( separate blood test for both of these ) if too many diuretics takes, the skin s too dry or dehydrated,. As regards the question on long term use. I am severely diabetic, have Hashimotos,, liver and kidney disease, end stage heart failure and most other cardiac problems and lots of other things I have been on 3 times recommended dose of a diuretic for many years, you can have some newer ones that have a little potassium protection in them. i have weekly blood tests. often you get used to one diuretic and it does not work well. Certain ones are also best for the kidneys. Very high potassium causes acute renal failure, coma etc, very low ,cardiac arrest. however this has to be looked at with the 4 main electrolytes and is very specialist, ie not many cardiologists and nephrologists under stand this. There is quite a lot of magnesium and potassium in some foods. I am sorry if this is confusing, complicated. if you want further info ,clckc on "reply to me"

best wishes,



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