Roma compared to Tiromel.... much of a muchness in BT results

[TiggerMe]

Follow on from my "Weak T3 post"

Well test results are in and they are very similar like for like.... so why does Roma just not make you feel as good as Tiromel?

Irritatingly I c@cked up the folate and Vit D so another stabfest is needed next week 😞

I shall have to go dig around and compare the exact ingredients, Roma has no lactose but I shall have to get my scientist head on 🤔

Is it just mind over matter?? Roma makes my chest feel tight 😕

[helvella Administrator Thyroid UK]

Have you tried taking Roma without the capsule? (See the Patient Information Leaflet for details.)

Just wondering if tat affects the rate of absorption or something like that.

[TiggerMe in reply to helvella]

Hi 🍄, I did for a couple of days and didn't notice any difference in the tightness... according to the results absorption is much the same if not a little better with Roma... I'm assuming the capsules are likely the same as the other myriad of capsules I take but I'm going to be a bit more forensic about it 🔎once I've been for a walk and put it out of my head for an hour... seem to remember the Tiromel pack has no English on it!

[helvella Administrator Thyroid UK in reply to TiggerMe]

From memory, they are pork gelatin whereas some other capsules can be made from among other possibilities:

Hydroxypropyl methyl cellulose (HPMC)

Starch

Starch polyvinyl alcohol (PVA)

Carrageenan

And could have various other ingredients (not just colours/opacifiers).

[TiggerMe in reply to helvella]

Back in the room... extended walk, bumped into the jolly old Berkeley Hunt 🦊filthy hounds!

Have now done a little translate and it seems Tiromel is purely L-Triiodotironin Sodium and lactose

Where as Roma, as you say gelatin shell (doesn't state pork which I'm better with) liothyronine sodium, maize starch and magnesium stearate which is used to stabilize and slow the breakdown and absorption so that it is absorbed in the bowel?? 🔎

So this would suggest Roma and Tiromel are absorbed in different areas... though both absorbed reasonably equally in my case... 🤔

I do already take magnesium stearate in the buffered Vit C which I have been using for the last 2 months and Aristo which I have been on for a while without issue 🔎

Amongst the long list of side effect for Roma it does include Angina pain though it states 'when exercising'

I shall give it another go without the capsule...

[helvella Administrator Thyroid UK in reply to TiggerMe]

Not quite!

Tiromel Patient Information Leaflet (in English) says:

6. PHARMACEUTICAL PROPERTIES

6.1. List of excipients

Lactose

Polyvinylpyrrolidone

Starch

Magnesium Stearate

Available at this link for now but that might change - if you want it, download a copy!

dropbox.com/s/mqtiorozn8o08...

I don't think anyone is specifically trying to ensure absorption takes place in one spot rather than another.

I don't think there is any reason to read into lists of side effects more than that they were the ones the company chose or were compelled to include. If one PIL is more recent than another, it could have details which were not available.

[TiggerMe in reply to helvella]

Ah, great... the bit in brackets just translated as excipients!

Not sure I like the sound of 'Polyvinylpyrrolidone' sounds like it ought to be on the record player rather than ingested 😝

Interestingly it does state to take one dose of Tiromel which I found worked best... might try that next with Roma

Thanks 🍄I've downloaded 🤗

Tiromel

[helvella Administrator Thyroid UK in reply to TiggerMe]

That's easy! Just call it povidone or PVP.

[TiggerMe in reply to helvella]

I'm loving the other rather dodgy translations on the sheet🤣

[jade_s in reply to TiggerMe]

I have some tiromel, i will translate & post what the leaflet says tomorrow. The bit in brackets on your pic just says 'see the usage instructions' (patient leaflet i guess). Lol.

I do remember it's GF, unlike the french cynomel which i hated lol.

[jade_s in reply to jade_s]

İ looked it up. Helvella's translation is correct. Dang i could've sworn they used to be corn starch, now it just says 'starch'. They warn about lactose "(from cow milk)" in several places but nothing about gluten. I don't react to them though so perhaps it's still corn.

[flitter-maus]

Interesting…I just didn’t feel as well on Roma. Back on Morningside Healthcare and back to normal after a few weeks. Not sure why Roma didn’t suit me🤷‍♀️

[TiggerMe in reply to flitter-maus]

I'm still taking it as no other options via NHS, seems to have settled in better now I've got the timings sorted and I am addressing my low cortisol issue 🤷‍♀️