Please help!!! Suggest some legit T3 supplier. I am very desperate for help. Inbox me please.

[MK85]

Hello everyone. I am very new to this forum and need some help. After six years of struggle with fibromyalgia and borderline thyroid I managed to convince my doctor to prescribe me levothyroxine which helped a bit with my pains but no help with my fatigue, weight gain and lots of other issues. I recently came to know about T3 (Tiromel) and very eager to try, it is my last hope and my doctor refused to prescribe that, which was quiet expected . Please can anybody suggest me any legit supplier to order Tiromel or any other brand of T3. Please help!!!! Inbox me privately please I know suppliers cant be discussed here...thanks

[RedApple Administrator]

MK85, Do you have some thyroid test results to share with members? Forum members don't like to encourage or facilitate anyone to take any thyroid hormone, especially not T3, without first seeing and discussing their thyroid levels with them.

[MK85]

Sorry abt not posting my test results earlier my, I have been borderline thyroid from last six years and latest test results were

Tsh 6.1

I haven't been tested for T3 or anything else by my GP, sadly. I have started levothyroxine 4 months ago I haven't been tested again for thyroid due to Covid and my surgery only offering emergency appointments so I am hanging in there. I am was on 25 mcg levo but 6 weeks ago after pleading my dr increased it to 50mcg but hasn't helped either so that's why m desperate to try T3 as my fatigue is beyond normal and weight is pilling on too. Please help!! From last six years my tsh has been between 5.5 and 6.

[SlowDragon Administrator in reply to MK85]

50mcg is only a STARTER DOSE

Bloods should be retested 6-8 weeks after each dose increase (or brand change) in levothyroxine

So it’s far too early to try adding T3

Likely to need at least 2 more 25mcg dose increases

guidelines on dose levothyroxine by weight

Even if we don’t start on full replacement dose, most people need to increase levothyroxine dose slowly upwards in 25mcg steps (retesting 6-8 weeks after each increase) until on full replacement dose

NICE guidelines on full replacement dose

nice.org.uk/guidance/ng145/...

1.3.6

Consider starting levothyroxine at a dosage of 1.6 micrograms per kilogram of body weight per day (rounded to the nearest 25 micrograms) for adults under 65 with primary hypothyroidism and no history of cardiovascular disease.

Also here

cks.nice.org.uk/topics/hypo...

gp-update.co.uk/Latest-Upda...

Traditionally we have tended to start patients on a low dose of levothyroxine and titrate it up over a period of months. RCT evidence suggests that for the majority of patients this is not necessary and may waste resources.

For patients aged >60y or with ischaemic heart disease, start levothyroxine at 25–50μg daily and titrate up every 3 to 6 weeks as tolerated.

For ALL other patients start at full replacement dose. For most this will equate to 1.6 μg/kg/day (approximately 100μg for a 60kg woman and 125μg for a 75kg man).

If you are starting treatment for subclinical hypothyroidism, this article advises starting at a dose close to the full treatment dose on the basis that it is difficult to assess symptom response unless a therapeutic dose has been trialled.

A small Dutch double-blind cross-over study (ArchIntMed 2010;170:1996) demonstrated that night time rather than morning dosing improved TSH suppression and free T4 measurements, but made no difference to subjective wellbeing. It is reasonable to take levothyroxine at night rather than in the morning, especially for individuals who do not eat late at night.

BMJ also clear on dose required

bmj.com/content/368/bmj.m41

bestpractice.bmj.com/topics...

Which brand of levothyroxine are you currently taking

What vitamin supplements are you currently taking, if any

Bloods should be retested 6-8 weeks after increase to 50mcg levothyroxine

For full Thyroid evaluation you need TSH, FT4 and FT3 plus both TPO and TG thyroid antibodies tested. Also EXTREMELY important to test vitamin D, folate, ferritin and B12

Low vitamin levels are extremely common, especially if you have autoimmune thyroid disease (Hashimoto's) diagnosed by raised Thyroid antibodies

Ask GP to test vitamin levels NOW if not been tested yet

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water .

Last dose of Levothyroxine 24 hours prior to blood test. (taking delayed dose immediately after blood draw).

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or thyroid antibodies or all relevant vitamins

List of private testing options

thyroiduk.org/getting-a-dia...

Medichecks Thyroid plus vitamins including folate (private blood draw required)

medichecks.com/products/thy...

Thriva Thyroid plus antibodies and vitamins By DIY fingerpick test

thriva.co/tests/thyroid-test

Thriva also offer just vitamin testing

Blue Horizon Thyroid Premium Gold includes antibodies, cortisol and vitamins by DIY fingerprick test

bluehorizonbloodtests.co.uk...

If you can get GP to test vitamins and antibodies then cheapest option for just TSH, FT4 and FT3

£29 (via NHS private service ) and 10% off if go on thyroid uk for code

thyroiduk.org/getting-a-dia...

monitormyhealth.org.uk/thyr...

Once you are on roughly correct dose levothyroxine and all four vitamins optimal.....only then is it time to consider possibly adding T3 .....but only if Ft3 remains too low

[SlowDragon Administrator in reply to MK85]

Have you had thyroid antibodies tested

If you have high antibodies this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease).

About 90% of primary hypothyroidism is autoimmune thyroid disease (hashimoto’s);

Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first

healthcheckshop.co.uk/store...?

Assuming test is negative you can immediately go on strictly gluten free diet

(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)

Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

drknews.com/changing-your-d...

restartmed.com/hashimotos-g...

Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease

ncbi.nlm.nih.gov/pubmed/296...

The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported

ncbi.nlm.nih.gov/pubmed/300...

The obtained results suggest that the gluten-free diet may bring clinical benefits to women with autoimmune thyroid disease

nuclmed.gr/wp/wp-content/up...

In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned

restartmed.com/hashimotos-g...

Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.

[MK85 in reply to SlowDragon]

Yes and the antibodies test was Negative

[MK85 in reply to MK85]

I was also tested for celiac and it was Negative too.

[SlowDragon Administrator in reply to MK85]

So as you already tested negative you can trial strictly gluten free diet straight away

[SlowDragon Administrator in reply to MK85]

NHS usually only tests TPO antibodies

You need TG antibodies tested too. Majority of Hashimoto’s patients have high TPO or high TG and high TPO antibodies, but significant minority only have high TG antibodies, NHS won’t test TG antibodies if TPO are negative

Ultrasound scan of thyroid can be very revealing

20% of Hashimoto's patients never have raised antibodies

healthunlocked.com/thyroidu...

Paul Robson on atrophied thyroid - especially if no TPO antibodies

paulrobinsonthyroid.com/cou...

[Hidden in reply to MK85]

My GP told me she didn't have any patients who were happy on 50mcg because it's "a really tiny dose".

I know it's hard to hear when you're desperate for a quick fix but getting well will take time. It's been 6 weeks so you can go back to your GP for another blood test now. You're aiming for a TSH of around 1.

GPs tend to only go by TSH so it helps to speak in the language they're expecting but I'd agree with other suggestions to test privately and get your T4 and T4 checked out.

Rest assured though, you're in good company here. Most, if not all of us, know exactly that feeling of desperation to be well again.

Good luck.

[RedApple Administrator]

MK85, You absolutely should not take any T3 without first testing your thyroid hormone levels. You need to find out what your TSH, FT4 and most importantly, your FT3 level is whilst on your current dose of 50mcg levo. You definitely shouldn't be even considering taking any T3 until you have this information.

[MK85]

Thanks for your advice.

[SlowDragon Administrator in reply to MK85]

Come back with new post once you get vitamin results....and thyroid results after 6-8 weeks on 50mcg

Levothyroxine doesn’t “top up” failing thyroid, it replaces it....hence why virtually every patient on levothyroxine will need to increase dose up to around full replacement dose ( many GP’s are completely unaware of this)

Absolutely essential to get all four vitamins tested and supplement to bring to optimal levels

If GP refuses to increase dose levothyroxine after next blood tests (assuming results show you need increase) then you will need to go over their head and see endocrinologist

Email Dionne at Thyroid UK for list of recommend thyroid specialist endocrinologists...NHS and Private

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