I'm glad they were able to do so many tests considering you were worried about not filling the microtainer. Are they sending you another kit out so that the folate test can be done?
CRP HS - 1.49 (0-5)
This result is fine.
Ferritin - 101 (13-150)
Good result.
Folate Serum - Re-test required
Hopefully you will get a new test kit.
Vitamin B12 Active - 78.2 (37.5 - 187.5)
Below 70 would suggest testing for B12 deficiency so there's no problem there. However, it's a bit low, I'd want mine over 100.
Vitamin D - 54.3 (50 - 175)
This is low. The Vit D Council recommends a level of 125nmol/L and the Vit D Society recommends a level of 100-150nmol/L.
To reach the recommended level from your current level, based on the Vit D Council's suggestions you could supplement with about 4,000iu D3 daily.
Retest after 3 months.
Once you've reached the recommended level then you'll need a maintenance dose to keep it there, which may be 2000iu daily, maybe more or less, maybe less in summer than winter, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with an NHS lab which offers this test to the general public:
Doctors don't know, because they're not taught much about nutrients, but there are important cofactors needed when taking D3 as recommended by the Vit D Council.
D3 aids absorption of calcium from food and Vit K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems such as hardening of the arteries, kidney stones, etc.
D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds if taking D3 as tablets/capsules/softgels, no necessity if using an oral spray.
Magnesium helps D3 to work. We need Magnesium so that the body utilises D3, it's required to convert Vit D into it's active form. So it's important we ensure we take magnesium when supplementing with D3.
Magnesium comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds if taking magnesium as tablets/capsules, no necessity if using topical forms of magnesium.
FT4 is 29% through range and FT3 is 23.51% through range. They're reasonably well balanced at the moment.
If your TSH really is 19.5 that screams that you need a dose increase, even if it's lower than that your FT4 and FT3 are far too low. The aim of a treated Hypo patient on Levo, generally, is for TSH to be 1 or below with FT4 and FT3 to be in the upper part of their reference ranges.
For conception and a successful pregnancy TSH should be below 2.5.
You need an increase in your Levo, 25mcg now and retest in 6-8 weeks, continue with testing/increasing until your levels are where they need to be for you to feel well.
Thyroglobulin Antibodies - 37.3 (0 - 115)
Thyroid Peroxidase Antibodies - 171 (0 - 34)
Your raised antibodies suggest that you are positive for autoimmune thyroid disease aka Hashimoto's which is where the thyroid is attacked and gradually destroyed.
Fluctuations in symptoms and test results are common with Hashi's.
Most doctors dismiss antibodies as being of no importance and know little or nothing about Hashi's and how it affects the patient, test results and symptoms. You need to read, learn, understand and help yourself where Hashi's is concerned.
Some members have found that adopting a strict gluten free diet can help, although there is no guarantee.
Gluten contains gliadin (a protein) which is thought to trigger autoimmune attacks so eliminating gluten can help reduce these attacks.
You don't need to be gluten sensitive or have Coeliac disease for a gluten free diet to help.
Unfortunately that isn’t a typo, at my last GP test my TSH was 25 so has come down a touch but nowhere near where it needs to be, especially as we are trying to conceive also. Went for GP bloods as well today so I’m hoping next week once the results are in for those he will increase my Levo.
With the Vit D, magnesium and Vit K2-MK7 is there an all in one supplement anyone has found that tackle more than one deficiency or do most take separately. I’m want to get my vitamins as good as I can.
Think I’ll definitely supplement for B12 as well, as you say there looks to be room for improvement there. Again any good recommendations for that?
Yes I had another test through the post today to re-test my folate serum so will hopefully do that Monday and I can post that result next week too.
Feels so liberating having an overall picture of what’s going on. So glad I took the advice on here to do this test.
With the Vit D, magnesium and Vit K2-MK7 is there an all in one supplement anyone has found that tackle more than one deficiency or do most take separately. I’m want to get my vitamins as good as I can.
I don't know of one with the right proportion of each individual active ingredient. You can get a combined D3/K2-MK7 supplement then you'd need a separate magnesium one.
I prefer to do all of them separately because I like to carefully choose my supplements, I try to use ones with no excipients if possible (potential for even more problems).
As you have Hashi's, you might do better with a D3 oral spray as this is absorbed through the mucous membranes in the oral cavity so bypasses the stomach. But, some Hashi's patients have done well with oil based softgels.
For an oral spray, look at BetterYou, this is popular with members, they do D3 and also a combined D3/K2-MK7. It does have quite a few excipients.
For an oil based softgel, look at Doctor's Best (this is the one I use), it has just 2 ingredients - D3 and extra virgin olive oil. Good quality and reasonably priced.
For a separate K2-MK7 I like Vegavero or Vitabay.
Magnesium you'd have to decide which form is best for you from the links. If you need the help of the laxative properties of magnesium citrate then Natural Vitality Natural Calm Original magnesium citrate powder is pure, no additives. I use this. You just add a small amount of warm water, and I add some orange juice to make a nice small drink. You start with a small amount and build up gradually to the dose you need, obviously if you get diarrhoea then you drop back a bit.
We don't supplement B12 on it's own, it needs a B Complex as well to balance all the B vitamins. However, as your B12 isn't very low then just a good B Complex should be enough as it will contain all the B vitamins. I like Thorne Basic B, some members use Igennus Super B. Both use the bioavailable forms of active ingredients.
When your folate result comes through, you are looking for it to be at least half way through range. If it's below range that can suggest folate deficiency for which your GP should prescribe folic acid, but even then you may do better with the methylfolate that's in the B Complex.
Don't start all supplements at once. Start with one, give it a week or two and if no adverse reaction then add the next one. Again, wait a week or two and if no adverse reaction add the next one. Continue like this. If you do have any adverse reaction then you will know what caused it.
I totally forgot to put my Levo dose on the main post. So I take 75mcg and 50mcg on alt days. It was increased from only 50mcg daily when I had the TSH of 25.
I know it’s so frustrating isn’t it. I feel like I’m back to square one. But I’m determined to help myself now. I have to push to be healthy. Took me a while to accept that fact x
Also ....guidelines by weight might help push for dose increase
Even if we don’t start on full replacement dose, most people need to increase dose slowly upwards in 25mcg steps (retesting 6-8 weeks after each increase) until on full replacement dose
Consider starting levothyroxine at a dosage of 1.6 micrograms per kilogram of body weight per day (rounded to the nearest 25 micrograms) for adults under 65 with primary hypothyroidism and no history of cardiovascular disease.
Hashimoto's frequently affects the gut and leads to low stomach acid and then low vitamin levels
Low vitamin levels affect Thyroid hormone working
Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.
According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies
While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first
Assuming test is negative you can immediately go on strictly gluten free diet
(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)
Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse
I have started to make gluten free choices but I know I need to be strict for it to have any effect. Need to look into this a lot more to get it right.
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