Interesting DIO2 study in Denmark: While poking... - Thyroid UK

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Interesting DIO2 study in Denmark

vocalEK profile image
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While poking through the clinicaltrials.gov web site with "hypothyroidism" as the search criteria, I came across an interesting sounding study:

clinicaltrials.gov/ct2/show...

Study Description

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Brief Summary:

Hypothesis: Variations in the deiodinase 2 gene and monocarboxylate transporter 10 gene is associated with improvement in quality of life after initiation of combination therapy with L-Thyroxine and Liothyronine in patients with persistent hypothyroid symptoms despite conventional L-thyroxine mono-therapy.

Purpose: To re-test this hypothesis in patients with continued perceived effect of Liothyronine treatment at least one year after initiation in a patient population more representing of daily clinical practice. The study will help determine whether testing of specific gene variations might predict longtime effect of combination therapy.

Contacts

Contact: Christian Z Jensen, MD52652688 ext +45christian.zinck.jensen.01@regionh.dk

Sponsors and Collaborators

Birte Nygaard

Investigators

Principal Investigator:Birte Nygaard, Ph.D.Herlev Hospital

The time to investigate this is now, as the study has not yet started recruiting subjects.

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Greekchick profile image
Greekchick

Thanks for posting, vocalEK. Very interesting - if I qualified (not long enough on treatment) and lived nearby to the study, I would love to have participated.

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