IGA deficiency and celiac disease: I was... - Thyroid UK

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IGA deficiency and celiac disease

dannyhashimotos profile image
7 Replies

I was diagnosed with Hashis when I was around 15. When I turned 23, a blood test came back with these results (I was eating gluten):

IMMUNOGLOBULIN A: 0.58 g/L (0.70-4.00)

Gliadin Antibodies (IgG): 0.3 U/ml (Negative: <7 / Equivocal 7-10 / Positive >10)

Gliadin Antibodies (IgA): 0.0 U/ml (Negative: <7 / Equivocal 7-10 / Positive >10)

Tissue Transglutaminase IgA: <0.01 U/ml (0-10)

Reticulin Ab's (IgA): Negative

Endomysial Ab's (IgA): Negative

The doctor recommended that I start a gluten-free diet. I've been gluten-free ever since and my overall health has been the better for it. Although I don't really get any sudden symptoms of cramps, vomiting, diarrhoea etc.

It's been a long time since I stopped eating gluten and I occasionally try and reintroduce it. I always end up getting symptoms of depression, anxiety and just get really angry at everything.

My questions is, does anyone else have these symptoms? Also, do my results look like someone who has celiac, should I get a biopsy?

Many thanks

D

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SlowDragon profile image
SlowDragonAdministrator

Majority of us with Hashimoto's are gluten intolerant not coeliac

You had a good doctor who had advised you try strictly gluten free diet. Pity more doctors don't also offer this advice

Your bloods don't show you have coeliac and there's no piont retesting once on gluten free diet

You know you feel better gluten free

You would need to eat high levels of gluten at every meal for minimum of 6 weeks before even considering retesting.

ncbi.nlm.nih.gov/pubmed/300...

The obtained results suggest that the gluten-free diet may bring clinical benefits to women with autoimmune thyroid disease

nuclmed.gr/wp/wp-content/up...

In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned

restartmed.com/hashimotos-g...

Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.

88% benefit from strictly gluten free diet

thyroidpharmacist.com/artic...

Going gluten free is a strategy that everyone with Hashimoto’s should try. In some cases, we see a complete remission of the condition; in other cases (88% of the time), the person feels significantly better in terms of bloating, diarrhea, energy, weight, constipation, stomach pain, reflux, hair regrowth, and anxiety.

todaysdietitian.com/newarch...

Many clinicians report that eating a gluten-free diet may help improve thyroid function in nonceliac gluten intolerance. “Getting gluten out is primary for patients with Hashimoto’s, even without celiac disease,”

dannyhashimotos profile image
dannyhashimotos in reply to SlowDragon

Hi SlowDragon,

Thanks for the reply. Yes, I had a great doctor at the time of those blood tests, it's a real pity I haven't had the same since!

Those articles are great, thanks for referencing them. I remember googling and finding similar opinions scattered around the internet before. It definitely seems that gluten intolerance is a problem with my body. I'll stick to my gluten-free diet.

BadHare profile image
BadHare

For some people, the issue in grains is phytates that inhibit mineral absorption, rather than gluten. I seem to be fine eating sourdough as the slow fermentation breaks down these as well as gluten, though this is still not good enough for anyone with coeliac disease.

As you say feel better without, why keep trying to eat something that makes you poorly? It only takes one breadcrumb to snowball gliadin antibodies, then your body will take 3 months to resolve this.

dannyhashimotos profile image
dannyhashimotos in reply to BadHare

That's interesting, I'll look in to that as well. I get no sudden symptoms from gluten but more of a gradual decrease in general health. Thanks for the reply!

BadHare profile image
BadHare in reply to dannyhashimotos

I had a diagnosis of coeliac as an infant, but was told I'd grown out of it, which I now know can't happen. From what I've read, being fed wheat is potentially the cause of my pituitary tumor, so there's more gluten issues than just digestion involved.

I have tried doing GF for >3 months several times, & felt no major difference, though I have a rapid intolerance to some other foods. My digestion doesn't feel quite right if I consume basic wheat products, so I stick to avoiding it unless it's really rude/inconvenient, & buy wholegrain sourdough for occasional bread consumption.

I read about phytates as I'm vegetarian (aside from NDT) so need to maximise mineral nutrient absorption as much as possible. There's quite a lot written, but this seemed straightforward if you're interested: parsleyhealth.com/blog/anti...

dannyhashimotos profile image
dannyhashimotos in reply to BadHare

Sorry to hear BadHare about the tumor, I hope you're on your way to better health!

I've got a vitamin D deficiency, and have had B12, zinc and iron deficiency in the past. There's something going wrong in my stomach/ immune system for sure as absorbtion of nutrients is definitely an issue.

Thanks for the link, I'm going to be reading in to this some more.

BadHare profile image
BadHare in reply to dannyhashimotos

Thanks!

The tiny tumour is still there & playing havoc with my hormones, but the past 4 years have been better since I followed the supplement advice on here, tweaked my diet, & started self-medicating. I'd never have guessed a lifetime of minor issues could be resolved with a few tiny hormone tablets. :)

Make sure you get your ducks in a row with regard to micronutrients as it only takes one deficiency (or excess) to skew everything we're trying to improve. I often have dilute apple cider vinegar or lemon juice before, or directly on meals to increse my stomach acid & enhance digestion & nutrient absorption. A grapefruit before meals works well too. I used to hate them, but now get cravings in summer. Prior to taking hormones, I was pedantic about my gut health & avoid processed food, but definitely feel the extra acid helps, though my teeth don't agree.

My immune system has improved as the hormones have increased my body temperature by a full degree. Good digestion is essential for improving immunity too. Lots to read here: google.com/search?client=fi...

There's so much to take in, so maybe spend 15 minutes a day going through posts on here, though it could turn in to hours. :)

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