Drug interactions with eltroxin: Can Nexium and... - Thyroid UK

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Drug interactions with eltroxin

Mauds profile image
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Can Nexium and Zydol interact with eltroxin. I'm on 80mg Nexium and was on 3 100mg slow release Zydol after my operation 8 weeks ago. I am now down to 1 Zydol each day and I'm just wondering if they interact with eltroxin and if that's why my thyroid is kicking up or is it a mix of all the drugs pumped into me after the operation and me spending 4 days in intensive care heavily sedated. It was a week after the operation that they started to give me my thyroid meds orally and I had to ask for them. I'm feeling awful hate dragging myself along with no energy.

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Mauds
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helvella profile image
helvellaAdministratorThyroid UK

For information, Zydol is a branded form of Tramadol.

Nexium contains a medicine called esomeprazole. This belongs to a group of medicines called ‘proton pump inhibitors’. They work by reducing the amount of acid that your stomach produces.

Mauds profile image
Mauds in reply to helvella

Sorry Helvella I should have explained what those meds were. Thanks

I understand that it is advisable to take esomeprazole (Nexium) approx 4 hours before/after levothyroxine (Eltroxin). I found that this time frame does make a significant difference.

Further good/useful information----

Drug.com

Drug Interactions Checker

drugs.com/interaction/list/

RXISK

Drug Interaction Checker

rxisk.org/tools/drug-intera...

Mauds profile image
Mauds in reply to

Could be where I've gone wrong so. I've been taking Nexium just after my thyroid meds

helvella profile image
helvellaAdministratorThyroid UK in reply to Mauds

A huge range of medicines, supplements, foods and drinks (other than water) can interact with levothyroxine in the stomach and gut.

The Patient Information Leaflets mention some things but they are far from complete.

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