Central Hypothyroidism

[NieuwOndaatje]

Hi, I'm new to the group and suspected Central Hypothyroid with low FT4 and FT3 and low TSH but not yet diagnosed as the Endocrinologists and GPs in the NHS seem to be less convinced of the merits of measuring anything beyond TSH. I'd be interested in any NHS Doctors and Endocrinologists that may have an understanding of CH from either a Pituitary or Hypothalamus perspective? There is so little understanding of the role of T3 and conversion issues from T4 to T3 here in the UK? Grateful for any insights you may have. Many thanks.

[ter1461]

Am I right in saying then that Central hypothyroidism is when there’s a problem with the pituitary and TSH not rising but Ft4/3 is low?

[helvella Administrator Thyroid UK in reply to ter1461]

Yes... but.

It can also be if the hypothalamus doesn't produce the appropriate amount of TRH (Thyrotropin Releasing Hormone) to tell the pituitary to produce enough TSH.

(Sometimes, if the issue is known to be with the pituitary it is called Secondary Hypothyroidism. And if known to be with the hypothalamus, Tertiary Hypothyroidism. But that distinction is not often made.)