Sensitive To Levo Increase: Hi All, I was... - Thyroid UK

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Sensitive To Levo Increase

Huddy1234 profile image
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Hi All,

I was diagnosed with under active thyroid 3 years ago and put on levo 25 mcg - in June this year I asked my doctor to increase to 50 mcg as I was aware that my dose had been kept low and I wasn't feeling any benefit from the medication. Main symptom being fatigue/tiredness/low energy!

I was taking Mercury Pharma 25's but when I collected the 50's the brand had changed to Actavis....... I had terrible side effects from these, low mood, insomnia, hot sweats day/night, anxious, sensitive, tearful, emotional.

I went back down to 25's and most of the symptoms subsided (thank god). I then asked for Mercury Pharma brand again and tried to introduce the increase twice a week but insomnia started to creep in.

I asked to be referred to an Endo and I see him on 1st September and had the below blood tests (I had eaten that morning and also taken my levo that morning as wasn't aware I was going to have blood taken)

I was told at my appointment that I had gone through an early menopause (I'm 46) which has obviously contributed to my tiredness etc.

I am currently on a 28 day trial of Teva brand levo (I am not lactose intolerant) but my endo said that some of his patients who are sensitive to levo increases sometimes tolerate this brand....... I am doing 25/50 on alternate days and am due to go back on 3rd November. I am 10 days in on these tablets and I haven't felt any bad effects or any good at present but do feel like they keep me awake at night.

Has anyone else been sensitive to increase on levo? Feels like a catch 22 as I'm obviously not on enough levo but can't seem to tolerate increase.

Is there something else I can try? Just like to gather as much information before my next appointment.

My main symptoms are tiredness/fatigue/low energy/brain fog/memory loss/ feel cold/thinning dry hair/low mood/no get up and go.

I have not had any weight gain - if anything I have lost a little but that maybe due to personal issues I currently have.

B12 - 490 (197-771)

TSH - 2.62 (0.27 - 4.20)

Free Thyroxine - 15.3 (12.0 - 22.0)

Free T3 - 4.2 (3.1 6.8)

Thyroglobulin Antibodies - 64.5 (0 - 115)

Thyroid Peroxidase Abs - 196 (0 - 33)

Cortisol - 327 (133-537)

Follicle Stimulating Hormone - 95.8 (25.8 - 134.8 Post Meno)

Luteinising Hormone - 45.9 (7.7 - 58.5) Post Meno

Ferritin - 53 (13 - 150)

Calcium - 2.41 (2.20 - 2.60)

Vitamin D - 103

Endomysium Negative

Tissue Transglutaminase - 0.3 (0-10)

Thank you for any advice you can give me.

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helvellaAdministratorThyroid UK

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