Adrenal Hormone Results - Help please

[LisaG28]

Hi All, Whilst i look to improve FT4 / FT3 conversion by going gluten free, optimising key nutrients as detailed on this forum, thought i should also look at my adrenal function.

Whilst under an Endo it was reported that my Cortisol was high following both a 24 hr urine and 1mg supression test (59), Addison's and Cushings were excluded and this was put this down to depression, Which i know i wasn't.

Having now found this site decided to retest myself via the Saliva test, Regenerus.

Have tried to add photo but is not allowing me to do so, so have detailed below:

Am - 7.0 Optimal Range - 18-35 Reference interval - 5.1 - 40

Noon - 2.6 6.0-12 2.1 - 16

Evening - 2.8 2.0 - 5.0 1.5 - 8.0

Night - 1.5 1.0 - 4.0 0.33 - 7.0

DHEA - *72 106 - 300

Comments from lab - DHEA typically declines with age, level measured is below reference rage, may warrant supplementation

I'm 51 and post menopausal

The suboptimal diurnal cortisol pattern is consistent with established (phase 3) HPA axis (adrenal gland) dysfunction.

In terms of DHEA, what are peoples thoughts on supplementation and if so is there a recommended brand / dosage?

The Cortisol results are concerning with regards the language used, should i be worried, what do i need to do or should i refer results to GP, though don't hold out much hope if she is struggling to understand the thyroid!!

Currently on 125 of levo

Any thoughts, help would be greatly appreciated in terms of deciphering the above and potential next steps.

Thanks all

[SeasideSusie Remembering]

LisaG28

On the report you had back from Regenerus, do your results follow the normal "curve", which will be shown on the graphic?

Your first 3 results are very low and your bedtime result is possibly a bit higher than it ought to be.

It's strange that your cortisol was high when tested by an Endo, but now your levels are low.

Optimal levels are

• Morning at the top of the range

• Noon approximately 75% of the range

• Evening close to 50% of the range

• Nighttime at the bottom of the range

DHEA is obviously very low. I can't advise about supplementing, it's not something I have done and personally I would think guidance from a medical professional is required there.

Dr Myhill's articles about interpreting cortisol tests:

drmyhill.co.uk/wiki/Common_...

drmyhill.co.uk/wiki/Adrenal...

[LisaG28 in reply to SeasideSusie]

Hi SeasideSusie, thank you for your prompt response, will certainly take a look at the links provided. I have also now attached a photo of the results, with the graph included. Does this shed any further light.

Many thanks

[SeasideSusie Remembering in reply to LisaG28]

Lisa

So your first 2 results seem to follow the normal curve, although very low, then samples 3 and 4 come back into range and aren't too bad. I can't advise how to deal with it, I'm not qualified or have enough experience, mine came back with Phase 2 HPA axis adrenal gland dysfunction and I am trying to raise my cortisol.

[LisaG28 in reply to SeasideSusie]

Hi, sorry to be a pain, will be my last question. When you say you are trying to raise your cortisol is this with the support of your gp or are you doing this outside of medical care. Fully understand that you're not a medic, but from your experience could these result be at the root of my poor ft4 ft3 conversio

Last results

Tsh 0.188 ( 0.27 - 4.20)

Ft4 20.9 (12 - 22)

Ft3 4.34 (3.10 - 6.80)

Many thanks in advance and it sounds as if I should try my Gp

Lisa

[SeasideSusie Remembering in reply to LisaG28]

LisaG28

My GP is TSH obsessed and all she wants to do is reduce my Levo and doesn't care that it will turn me into a zombie and make me virtually bedbound as it has before. So I just accept my prescription for Levo and then look after myself my way with what I have learnt over the years. If I discussed adrenals with her it would just start the whole thing off again so I don't bother.

Adrenals and thyroid work together, so if adrenals are out of whack then thyroid wont be in a good place either. It's important to address adrenals, nutrient levels and then hopefully thyroid sorts itself out with the correct dose of replacement hormone.

[QUE6T-33 in reply to SeasideSusie]

Hello Seasidesusie, your Endo did a 24 hour urinary Cortisol which was elevated, & then you had a Regenurus Saliva test that was suboptimal.

How long was it between tests ? Saliva reflects tissue level of Cortsol,

urine is free unused cortisol (I believe). But interesting how different results were.

[QUE6T-33 in reply to QUE6T-33]

Sorry, meant to address that reply to Lisa 🙁

[LisaG28 in reply to QUE6T-33]

Morning, Endo undertook both a 24 hr urine test and overnight suppression test in late 2015, suggested i was obviously depressed, results over range and that i required anti depressants!!!, asked that GP retest 6 months later. Result at GP 2016, had improved although were still elevated. No interest as to the root cause given they had ruled out Cushings / Addisons. 2 years later my morning, afternoon cortisol are now low, coupled with low DHEA. No clue as to what is going on, so have started taking adrenal support and will retest. If no improvement will go back to GP as i believe my adrenals, hormones are the missing link in restoring optimum health

[QUE6T-33 in reply to LisaG28]

Yes, agree with you. Keep smiling 😊