My latest results, opinions please. These are the doctors comments (from Blue Horizon)
The combination of normal TSH and low free T4 levels, with a normal T3 level, would be unsurprising if you are taking T3 form of thyroxine - is this the case? If so, it is looks as though your medication regime is likely to be satisfactory, although if you have any doubts, please discuss your ongoing thyroid medication dose requirement with your usual doctor. If you are not taking thyroxine, the low level of free T4 might suggest a developing thyroid problem - and again, a discussion with your usual doctor would be wise.
The ferritin level is high. In addition to excess iron supplementation, raised serum ferritin can be a sign of inflammation or infection although this is less likely with a normal CRP (as it is here). Less commonly, higher ferritin levels can result from damage to bone marrow or liver, genetic conditions, following blood transfusion, and in chronic anaemias such as thalassaemia. If it is unlikely that iron supplementation is the cause of this elevation then more formal iron studies would be useful.
The Vitamin B12 level is insufficient. Some experts believe levels of 400-500 are desirable and that levels below this may lead to symptoms. Low Vitamin B12 levels can lead to Pernicious Anaemia (PA), a state of deficiency of the red blood cells in which there is reduced quality and number. Characteristically, the red blood cells are enlarged in this state (if the deficiency is severe and longstanding). Vitamin B12 is commonly found in many foods, particularly meats. Deficiency can develop if intake of the vitamin is reduced or if absorption from the gut is impaired. Poor absorption owing to a deficiency of Intrinsic Factor (IF) is the underlying reason for PA. Vitamin B12 deficiency in the longer run can lead to nervous system disorders - with sensation changes, loss of power or co-ordination, gut disorders and (rarely) dementia or mental illness. Lower level deficiency has been associated with a range of symptoms such as fatigue, memory impairment, irritability, depression and personality changes. Supplementation with Vitamin B12 is likely to be of benefit - please discuss this finding with your usual doctor.
I’m not supplementing with T3 and I’ve never supplemented with iron. Nor have I ever had low B12; history, both mother and sister were diagnosed with PA at much the same age as I am now, mid 60s and Mum was diagnosed with hypothyroid.
I intend to see my GP but I want to be prepared, any suggestions of how I should deal with this would be gratefully received. Can supplementing with B12 be effective? Slow dragon mentioned haemachromotosis as a possibility, my ferritin has been raised in all the blood tests I’ve had over the last 5 years or so. Would I expect to be medicated for the low free t4 levels?
Thanks in advance for any help with this.