Latest results, can anyone help me understand t... - Thyroid UK

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Latest results, can anyone help me understand them?

curlyclaz profile image
5 Replies

Blood test requested due to symptoms of hair loss, brain fog and fatigue.

Requested TSH, t4, t3, antibodies, b12, iron and vit d. Told all normal.

This is what I have (Not sure which are which on some)

Erythrocyte 5mm/h (0-12)

Serum vit B12 453 ng/l (191-663)

Serum folate 4ug/l (3.9-26.8)

Serum ferritin 30ug/l (10-150)

Serum total 25-OH vit d level 80nmol/l (>50)

Thyroid peroxidase AB (RL9217) normal no action

Significant level of tpo antibodies

Thyroid peroxidase antibodies 260 kiu/l

Tsh 1.09 (0.27-4.20)

Can't see t4 or t3 ?

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curlyclaz profile image
curlyclaz
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Judithdalston profile image
Judithdalston

Just checking, you don't take any thyroid 'meds', nor had a diagnosis before? You only have 1 thyroid blood result here:TSH which at 1.09 is relatively good, but this also could be lower if your FT4 and FT3 needed to be raised with thyroid 'medication', but without results can't tell. I am a bit confused over the 3rd, 4th, 5th lines from bottom of results regarding thyroid peroxide/TPO as it mentions 'significant levels' and 'normal no action'; there is a figure, 260 Kiu/ L but no range. TPO is one of two thyroid hormone autoimmune antibodies, the other being thyroglobulin; high levels mean you are Hashimoto's ie have antibodies are in your blood, and when they 'get going' they mistakenly believe your thyroid gland is 'alien', attack it, and dead cells, complete with some thyroid hormones, are dumped into the blood as waste. If this happens your thyroid blood results, can fluctuate, and the TSH result is certainly not enough to monitor you. Hashimoto's can also be characterised by poor gut absorption meaning essential vitamins and minerals can be low : optimum Vit D, B12, folate and ferritin blood levels are needed, at the upper end of ranges. Your folate and ferritin are particularly low and need improving. Look at SeasideSusie's posts/replies here re good Vit/ min health, supplements etc. Though you might not be hypothyroid at the moment, you might become so. Some try to control their antibodies by going gluten-free, even dairy free. Again search this forum- at the very top of page you can search Tyroid Uk, and see 'related posts' to right.

curlyclaz profile image
curlyclaz in reply to Judithdalston

Sorry, I'm on 125mg levo already, diagnosed hypo in October.

Judithdalston profile image
Judithdalston in reply to curlyclaz

Ok, most of what I said above still holds true. But what about 3 lines re autoimmune antibodies that I couldn't understand as was near bottom of your results?

curlyclaz profile image
curlyclaz in reply to Judithdalston

That is all I have, I don't understand them . Will try to get a GP appointment to discuss.

SlowDragon profile image
SlowDragonAdministrator in reply to curlyclaz

Your folate and ferritin both too low

Ask GP to run full iron panel for Anaemia

Ferritin needs to be at least half way in range i.e. About 70

Eating liver or liver pate once a week should help, but GP may prescribe ferrous fumerate

Folate is low. If GP doesn't prescribe folic acid then supplementing a good quality vitamin B complex, one with folate in may help

If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 3-5 days before any blood tests, as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

Your TPO antibodies are high, this means cause of being hypothyroid is due to autoimmune thyroid disease also called Hashimoto's

Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten.

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

Ideally ask GP for coeliac blood test first

amymyersmd.com/2017/02/3-im...

chriskresser.com/the-gluten...

thyroidpharmacist.com/artic...

scdlifestyle.com/2014/08/th...

drknews.com/changing-your-d...

thyroidpharmacist.com/artic...

But don't be surprised that GP or endo never mention gut, gluten or low vitamins. Hashimoto's is very poorly understood

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