Horrible side effect of Cytomel: Triiodothyronine... - Thyroid UK

Thyroid UK

137,649 members161,425 posts

Horrible side effect of Cytomel

Shaun_m profile image
18 Replies

Triiodothyronine, Free, Serum: 1.9 (2.0 - 4.4)

Thyroxine T4 Free: 1.82 (.82 - 1.77)

TSH: 2.22 (.45 - 4.5)

Reverse T3: 32.4 (9.2 - 24.1)

Ferritin: 131 (30 - 400)

Folate: 14.9 (>3.0)

B12: 1636 (232 - 1245)

Vitamin D: 40.5 (30 - 100)

Currently on 112 MCG Levothyroxine and a multivitamin.

Above are my recent lab results. I was given great advice already on this forum about adding Cytomel, but it makes me unwell (irritated, arms feel like lead, physically drained, shallow breathing to the point where I stop breathing and I have to force myself to breathe). I tried taking 10mcg of Cytomel instead of 5mcg thinking I needed more, but it didn't work. The same type of thing happened when I tried Armour Thyroid.

Are there other natural ways of boosting my T3 levels or other T3 medication I should try? I appreciate the input.

Written by
Shaun_m profile image
Shaun_m
To view profiles and participate in discussions please or .
Read more about...
18 Replies
Clutter profile image
Clutter

Shaun_m,

It's unusual to have FT4 over range when TSH is 2.2. It looks like the high FT4 is converting to rT3 instead of T3. You could try reducing Levothyroxine by 25mcg to 87.5mcg which should reduce FT4 and rT3 and see whether FT3 rises.

How long did you try 5mcg and 10mcg T3?

Shaun_m profile image
Shaun_m

Last Thursday and Friday, I tried 10mcg. Since then I’ve been trying 5mcg and 10mcg about every other day. I’ve tried to take them at different times of the day, but still having the same issues. The shortness of breath is the scariest symptom I’ve had.

Clutter profile image
Clutter in reply to Shaun_m

Shaun_m,

I'd skip the T3 for now and see whether reducing Levothyroxine dose helps. Give it 3-4 weeks on the reduced dose to let FT4 and rT3 drop and then try 5mcg T3 daily again.

Shaun_m profile image
Shaun_m

Ok. I appreciate it. I will see if my doctor will send the reduced dose prescription to my pharmacy.

Kell-E profile image
Kell-E in reply to Shaun_m

If you skip a pill and a half per week of the 112mcg, that will give you 88mcg.

Shaun_m profile image
Shaun_m in reply to Kell-E

Awesome thanks!!

Kell-E profile image
Kell-E in reply to Shaun_m

You are welcome. I've had to change doses a lot and we have to pay each time for new rx, so needless to say it was cheaper to improvise.

You can always calculate it by:

Number of pills you take each week times the number of micrograms. Divide by 7 and you have the new dose in mcg. In your case 5.5 times 112mcg = 616mcg.

616mcg divided by 7 = 88mcg

Shaun_m profile image
Shaun_m in reply to Kell-E

Thank you for this 😊

Cro-magnon profile image
Cro-magnon in reply to Kell-E

Hi Kell-E

This formula is it for calculate the mcg of Cytomel? In what is based?

Seems very interesting, I am thinking on starting taking Cytomel but as my GP doesn't want to do neither test nor even discus adding T3 on my meds, I was wondering if I might need to do by myself, but seems very scary as well.

Any information will be appreciate it.

Kell-E profile image
Kell-E in reply to Cro-magnon

No, this is a way to utilize one strength of Levothyroxine to take a different dose.

The approximation for the strength of Cytomel vs Levo is that Cytomel is 3 times stronger than Levothyroxine per mcg.

Cro-magnon profile image
Cro-magnon in reply to Kell-E

Thanks for replying Kell-E,

I don't understand what this mean but I will figúrate. 😅

Kell-E profile image
Kell-E in reply to Cro-magnon

It means 10mcg of Cytomel = 30mcg of levothyroxine (Synthroid)

JennaShi profile image
JennaShi

Im mfprtunately having the same issues wth Cymotel. Thank you Clutter for sharing. I hope you feel better soon Shaun_m

Shaun_m profile image
Shaun_m in reply to JennaShi

Thank you and I hope you figure out the medication issue. I didn’t take my Levothyroxine last night and I ended up taking 5mcg of Cytomel today because I could barely think and the side effects weren’t as bad. It’s a tough road but I’m grateful for this community 😊

JennaShi profile image
JennaShi in reply to Shaun_m

I hope you get all figured out. Im glad your symptoms werent as bad. Yes I totally agree with you, this a great community!

LAHs profile image
LAHs

Selenium is the catalyst you need to convert T4 to T3. If you cannot take T3 externally (i.e. a pill), measure your selenium level, if it is low then there is your problem. Either eat two Brazil nuts per day or start taking a Selenium supplement. (BTW, only TWO Brazil nuts, excess Selenium will cause other problems)

Now, having said that, vitamins B12 and Vitamin D3 also contribute to T4 to T3 conversion but Selenium is the main one.

Shaun_m profile image
Shaun_m in reply to LAHs

Thank you LAHs 😀

EbonyEvans profile image
EbonyEvans in reply to Shaun_m

Brazil nuts need to be organic and state ‘grown in Selenium rich soil’ to be beneficial.

You may also like...

Cytomel side effects

My cytomel was recently increased to 5 mcg 1/2 tablet 3 times day and Synthroid 75 changed to...

Synthroid vs Cytomel's effect on TSH Suppression

and there, can I only take 5 mg Cytomel per day (instead of 10 mcg Cytomel per day) along with the...

Starting T3 Side Effects

Endocrinology. My new 5mcg pills arrived today, and the plan is I take 5mcg 3 times a day, total of

In your experience the difference of effects between Unipharma T3 and Cynomel/Cytomel? And between Cynomel/Cytomel?

difficult to acquire I was thinking of trying Cynomel or Cytomel and wondered of others experiences...

Medications for increasing Free T3 and side effects?

Because my free T3 is on the low end (2.5), (I am on .75 mcg of Synthroid: TSH is 2.29 and have...