Well she can thank whatever fool reduced dose from 175mcg to 50mcg for the fact her FT4 is below range and TSH so high. She was very overmedicated to have FT4 40.3 and FT3 11.2 in Novement but dose adjustments are supposed to be gradual not swingeing. Her dose should not have been reduced by more than 50mcg in one go and 25mcg is more usual. Her GP or endo needs to increase dose, I'd say initially to 100mcg and retest in 6-8 weeks.
The goal of Levothyroxine is to restore the patient to euthyroid status. For most patients that will be when TSH is 0.2 - 1.0 with FT4 in the upper range. FT4 needs to be in the upper range in order that sufficient T3 is converted. Read Treatment Options in thyroiduk.org.uk/tuk/about_... Email dionne.fulcher@thyroiduk.org if you would like a copy of the Pulse article to show your GP. The Thyroid UK office opens on 3rd January.
Thyroid peroxidase and thyroglobulin antibodies are positive for autoimmune thyroid disease (Hashimoto's). There is no cure for Hashimoto's which causes 90% of hypothyroidism. Levothyroxine treatment is for the low thyroid levels it causes. Many people have found that 100% gluten-free diet is helpful in reducing Hashi flares, symptoms and eventually antibodies.
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