High TGAB: Hi, can anybody tell me what it means... - Thyroid UK

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High TGAB

Sadienerin
Sadienerin

Hi, can anybody tell me what it means if test shows high thyroglobulin antibodies please (72) . All others are well within range. Have been told I was borderline low t4 in past, but no treatment given. Had extensive thyroid bloods done privately, which showed high tgAB. I have symptoms of hypothyroidism including weight gain, significant hair loss, dry skin, tiredness, weakness etc. I also have palpitations which was also detectable via ecg and showed other abnormalities (being investigated at the moment) and have high cholesterol. Thank you.

16 Replies
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Clutter
Clutter
in reply to Hidden

Sadienerin,

Thyroglobulin is usually used to monitor treatment in patients who have had thyroid cancer and thyroidectomy. There is no point in measuring thyroglobulin otherwise because thyroglobulin can be elevated in anyone who still has their thryoid gland.

Sadienerin
Sadienerin
in reply to Clutter

Ok, so it's nothing to worry about then! Thank you 😊

Clutter
Clutter
in reply to Sadienerin

Sadienerin,

Were TSH, FT4 and FT3 tested?

Sadienerin
Sadienerin
in reply to Clutter

Yes all tested. All well within range this time, but antibodies high. Been borderline low in past but drs wouldn’t treat as it was still within range.

Did you really mean thyroglobulin or did you mean thyroglobulin antibodies?

labtestsonline.org.uk/under...

labtestsonline.org.uk/under...

Thyroglobulin antibodies were high, sorry. Have edited post now x

Clutter
Clutter
in reply to Sadienerin

Sadienerin,

High thyroglobulin antibodies means you are positive for autoimmune thyroid disease (Hashimoto's). There is no cure for Hashimoto's which causes 90% of hypothyroidism. Levothyroxine treatment is for the low thyroid levels it eventually causes. Many people have found that 100% gluten-free diet is helpful in reducing Hashi flares, symptoms and eventually antibodies.

chriskresser.com/the-gluten...

thyroiduk.org.uk/tuk/about_...

Sadienerin
Sadienerin
in reply to Clutter

Oh ok, thank you. So if all your other measures are within range, they won’t treat you despite symptoms? X

Clutter
Clutter
in reply to Sadienerin

Sadienerin,

No, NHS won't treat until either TSH is over range or FT4 below range.

Sadienerin
Sadienerin
in reply to Clutter

Ok just as I thought. Thank you

B12jab
B12jab
in reply to Sadienerin

Hi can I ask how you got on! I too have high Tg antibodies did you receive any treatment? Many thanks and hope you are well x

Sadienerin
Sadienerin
in reply to B12jab

Hi, not a lot unfortunately. Saw an endocrinologist, who said until my TSH reaches 10, I can't have teatment. If anything, my tsh is very low at the moment <1 , so don't think, I'll ever have treatment. There's a chance due my tsh being so low, that the problem lies with my pituitary gland having looked at answers, and research, in which case it's unlikely my tsh will rise, but the endocrinologist won't accept it. I've started high strength biotin, and try to stick to gluten free when i can, but gluten free bread is rank! So slip occasionally when I have a sandwich with normal bread. Gluten free pasta, and various sauces are nice, so they're not a problem. It has helped a bit, energy wise, but still tire easily, have significant hair loss, which is also dry and straw like, dry skin, weight that won't budge etc. Hope you find a more sympathetic and understanding Dr. Best wishes xx

Hi just come across your post,your results are a lot like mine I too have a high Tgb antibodies results but normal Tpo I’m so worried can I ask what the outcome was for you I’ve read some things that have really worried me about high Tgb antibodies alone,I hope your well x

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