Hi all - I was diagnosed back in Feb (TSH 9.1) and put on a dose of 25mcg, further blood test in March revealed TSH 11.07 so increased to 50mcg. Next blood test was 'normal' result (TSH 0.65) in May and last blood test at end of July TSH was up to 14.97. GP has increased my dose to 100mcg and I have now been taking for just over a week at new level and feeling awful! Is this because my body is catching up with the new dose? I am positive for Hashi's (was tested in March with a result of 80 IU/ml (range <34 IU/ml) but haven't been tested at any other time for this. Feeling exhausted and hoping that this is just due to dose adjustment. Any thoughts on this appreciated - thanks.