Genova Results - opinion please?: Could I have... - Thyroid UK

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Genova Results - opinion please?

Harebell profile image
3 Replies

Could I have advice on my Genova Thyroid Plus results please?

Genova Thyroid Plus – reference range in brackets

Total thyroxine T4 - 69 (58-161 nmol/L)

TSH – 0.30 (0.4-4.00 microiu/mL)

Free thyroxine T4 – 12.9 (11.5-22.7 pmol/L)

Free T3 – 3.1 (2.8-6.5 pmol/L)

FT4:FT3 ratio – 4.2

Reverse T3 – 0.24 (0.14-0.54 nmol/L)

Thyroglobulin (TG) - <32 (<=40iu/mL)

Peroxidase (TPO) – 34 (<=34iu/mL)

Have calculated my Free T3/Reverse T3 ratio – 12.9

I have been on Thyroxine 150mcg and Liothyronine 10mcg for years. I didn’t take them in the 48 hours prior to having my blood taken and it was done fasting. I have ME with many associated problems. I’m confused because TSH is low, but T4 and T3 are at the low end of the scale too.

What should I do re medication? Cut out T4 for a while and take T3 only to get the reverse T3 down? Try NDT? Very confused!

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Harebell profile image
Harebell
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startagaingirl profile image
startagaingirl

Hi , the advice is that t4 shouldn't be taken for 24hrs before test and t3 12 hrs. So if you left 48 hrs that explains why both tsh and ft3 are low. Afraid the ft3 is falsely so and I don't know of a reliable calculation that can be done on it.

It is, however, likely that you are still undermedicated, but by how much I don't know. Have you had any tests done for vit d, vit b12, folate and ferritin? Deficiencies are almost universal with hypo and can cause seriou issues themselves and through poor conversion and use of thyroid hormones.

Since your antibodies show hashis, are you on a strict gluten free diet?

Gillian

silverfox7 profile image
silverfox7

Plus I was told that when taking anything with T3 in it then the results are read differently. TSH will be suppressed, FT4 can fall down range and even down to half way but FT3 should be high in the range so yes under medicated and the only reliable reading is FT3 which must not consistently be over range. If it is slightly over it may be something like a virus that you are t even aware of that's pushed it up so retest in 4 weeks and then drop down a quarter if it is still over.

Harebell profile image
Harebell

Thank you both for your replies.

Does it look like a Reverse T3 problem?

Gillian, yes I have been gluten free for ?a couple of years and presume it has helped a lot as the antibodies used to be much higher than that (can't remember figures offhand) but it's a massive improvement from before.

Yes, I'm very low in ferritin, folate low but okay, Vit D still to be tested. My Active B12 is high, over range, which I don't understand at all, as I'm not supplementing B12.

So, do I try to improve those deficiencies first before changing thyroid meds dosage, or do I start with changing thyroid meds?

Thank you Silverfox. I've been reading more recently about just ignoring TSH, but then I go and read something about the dangers of low TSH :-( My system is all screwed up anyway, so I think your advice of going by the T3 alone is very good (and just by how I feel symptom wise).

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