I have congenital Hypothyroidism so have been on this battle for my entire life. Recently just went back to the hospital Endocrinologist for a check up and to see if it would be worth changing back to Levothyroxine. This was for 1 main reason, Liothyronine is bloody hard to get hold of most of the time and if i can get the same effects on the Levo then i would continue with that. The advantages of Levo mean that i can take the lot in the morning and not spread it around throughout the day. This was just an experiment as i have been told that if my blood test results dont show that Levo works better i am able to go back onto Liothyronine. But the slight twist is i have to take it as soon as i wake up with water and a minimum of 30 minutes prior to food or other drink as my other meds could affect the absorption rate of the Levo. HAS anyone else been given this advice and did it actually work? I am on 350mcg of Levo compared to the 60 of Lio which is like for like dosage. I will be getting bloods done every 6 weeks until Jan when i am due to go back.