Thyroid UK
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Ldn and/or thyroid peeps, any thoughts? Ldn capsules vs liquid?

Any thoughts on what has happened here and why? My tsh has shot up between Feb and Aug and the only change I can think of that might have made a difference is that I now take ldn capsules instead of liquid. I'm back and forth travelling and I kept leaving it in fridges so I swapped to the capsules.

Since starting ldn my levo has been reduced. I suspected it was the ldn somehow facilitating the thyroid meds and the tests checked out so I didn't mind reducing. I haven't felt really well in about two years so I thought it was worth a try in case being on more meds was making me feel not so great.

My last results, in Feb, were v good, tsh low/suppressed and t3 high in range. Gp was satisfied that if the t3 was in range I could remain on my dose. Now this summer I feel really pretty pants so I up the dose experimentally, taking 75/50 levo and 10 t3. Eventually up it again to 75 (same t3).

Gp ordered a tft as part of my meds review and hey presto, my tsh is over 5 and everything else looks a little fair to middling. (Apologies, I don't have the actual test results from Feb but I did check them myself at the time and they looked ideal to me.)

This is Aug 16:

TSH 5.17 (0.34 - 5.6)

FT4 8.3 (7.5 - 21.1)

FT3 5.4 (3.8 - 6.8)

To be fair, my tsh is usually v low and t3 good (maybe around 6) and now tsh v high but t3 still not bad. Wth?

All suggestions welcomed.

4 Replies


I think you'll either need to see whether reverting to liquid LDN improves thyroid function or increase thyroid medication dose if you intend to continue with the LDN tablets.


Thanks Clutter, that would be the experiment which would show exactly what's going on I guess, but the problem with that is that I need to not be so undermedicated asap. Every day I'm losing more hair and I feel dreadful.

And I'm concerned that if the ldn isn't improving my thyroid function, what is it doing if anything?

I think I'll write to the pharmacy to see what they say.

I suspect most people are taking the liquid which I guess means there isn't much to say about the caps. They are just the powdered ldn in a capsule as opposed to in a linctus, so I find it hard to understand how they would work differently.



In that case you should increase your Levothyroxine dose by 25mcg and retest in 6-8 weeks.

Perhaps liquid LDN is better absorbed than the powdered capsules.


Yes thanks, I did the increase two weeks ago.

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