Thyroid UK
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Early days on T3

Good morning. I was on 300 mcg of levothyroxine but it did not work. I am trying T3, adding it to a reduced dose of T4. I began on 250 mcg of T4, with 10 mcg of T3, (5 plus 5). I was brilliant for five days, even went for a gentle walk, an unheard of thing! But on Day 6 I began to feel the old familiar tiredness creeping and now on Day 7 I feel back to square one.

Does anyone think I have gone too quickly? Or taken too much T3? Or not enough? Or got the combination wrong?

I am very grateful for the help I have been given in the last by this forum. Thank you.


4 Replies

New research has shown that a ratio of T4 to T3 should be 3 to 1.

Go to page 80 - the first column on left-hand side - first para on the following link:-


Thank you, Shaws!



Joeyis7, 10mcg T3 is equivalent to 30mcg T4, so by reducing 50mcg T4 you may be slightly undermedicated. It was fine while the higher dose T4 was washing out but you probably need another 10mcg T3 now it has.


I am not a medical professional and this information is not intended to be a substitute for medical guidance from your own doctor. Please check with your personal physician before applying any of these suggestions.

1 like

Thank you, Clutter. I had a hunch that might be it. I will adjust carefully. Grateful for advice.



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