I have started a new thread for this but if you're interested in the angst I've had in the last 18 months you'll find me elsewhere on this wonderful site.
Last Saturday, after seeing Endo the day before, I started on a combi dose of T3 and Levo - 75 mcg Levo and 15 mcg 3 x a day ofT3 (Liothyronine). The Endo said it would be ok for me to titrate the T3 upwards until I felt better as long as I didn't overdo it. He'd tried me on a combi dose before but my FT3 went too high and I didn't feel much better than when I was on Thyroxine only. Originally he put me on 10 mcg T3 twice a day - first dose in morning and second dose at night amd I had to take the Levo in the morning with the first dose of T3. This time he told me to start off at 5 mcg morning and night. It didn't take me long to realise that the T3 was 'running out' on me after about 5 hours, so I started to take a third dose of 5 mcg T3 mid afternoon.
After only 5 days I can feel some improvement in energy, mood, less joint and muscle pain and no migraine (touch wood). I realise I've got some way to go because I've still got some of the hypo symptoms like constipation. Having bloods done in a week's time and results will give me a pointer. TSH needs to be suppressed at between 0.05 and 0.1. It was 0.2 last time with an FT4 of 22 and an FT3 of 3. he'd put me back on Levo 100 mcg with no T3 after he thought he'd misread a conversion problem because on the first combo dose I checked in with FT4 of 10 and FT3 od 10.7.
I now realise of course that I was having 20 mcg of T3 in an eight hour period and then no more for 15 or 16 hours. I have high hopes that I can soon get this sorted but have to take it a step at a time with blood tests every fortnight. I'm fortunate that he's letting me do this.
I'm also very lucky that my GP has no problem with the very expensive T3. Since starting on the 5 mcg a week ago, I've been splitting the 20 mcg tabs into quarters - not easy! I took my new prescription to the pharmacy yesterday and the pharmacist asked why I'd got 20 mcg. I aid I didn't think they came in 5s and if they did I was sure they were very expensive. Lovely man said cost should not be a limiting factor and he thought that splitting them into 4 was not only difficult but also too random for accurate dosing. He spoke to my GP and yesterday phoned me to say that they were waiting for me.
They're Paddock 5 mcg. They are bigger than the 20s. I dread to think what they cost as pharmacist told me that the 20s I've been having are £148 for 28 (in the plain brown bottle). I do worry about the NHS budget, particularly as everyone is so nice about giving me this stuff ( and the bucket load of other stuff I have!) but I'm also worried that at some point some 'high up' will stop them just as I'm getting sorted. I just couldn't afford to buy them.
I read the very long leaflet that came with the Paddock. They say the dose should be once daily in the morning.......??? I've read this elsewhere too but can't reconcile that with its very short half-life.
So - getting there I think. At least I'm on the rught track I think.
Any comments or information re any of the above will, as always. ne very much appreciated xxx