I had underactive thyroid then overactive now a... - Thyroid UK
I had underactive thyroid then overactive now autoimmune thyroid and pernicious anemia is this possible
Yes - it is possible.
You very likely had autoimmune thyroid disease throughout. But at one point resulting in low thyroid hormone levels, at another point high levels.
When someone has one autoimmune disease, it is not uncommon to have another one. And pernicious anaemia is a relatively common one alongside thyroid.
helvella Thank you for prompt reply do you know what I could take to help with symtoms
Yes, I got b12 injection from Doc and she has given me more to take every 6 weeks. still to stay on 75g of thyroid med. feeling very tired, tingling in my legs, not sleeping very well and feeling low
Did you have a loading dose (6 injections over 2 weeks), or just the one?
one injection only and to take 4 more, one every 6 weeks
No wonder you're not feeling better! Yet another inept GP, not following the guidelines laid down for treating this disorder.
The absolute basic minimum level of treatment for PA is a loading dose of 6 injections over 2 weeks, followed by a maintenance jab every 3 months for life. However, it quite clearly states in the BNF (section 9.1.2), which is the little book GP's pull down off the shelf when they're deciding on dosages, that if you have neurological involvement (which you do - tingling) the treatment is an injection every other day until no further improvement, followed by a 2 monthly maintenance jab. This info is found here under "Dose":
evidence.nhs.uk/formulary/b...
This same information can be found here under the section "Management":
patient.co.uk/doctor/Pernic...
Other important co-factors are folate and iron, anything low or low normal will prevent you from getting the best from these jabs. Have you ever had folate and ferritin tested? Getting the treatment for your PA right is important, and it should have the added benefit of improving your thyroid function.
Are you a member of the Pernicious Anaemia Society? You can read much of the website for free (the forum is particularly enlightening) but if you want to post your story you need to be a member. It costs £20 but it's money well spent IMHO. A link to my story is here, just to give you an idea: