I am nervous about taking this medication. Have not seen the most positive reviews on it. But, I need to get off Senna-Lax. Have been on it way too long, but it's the only thing that works, as my IBS-C is Very chronic and severe. Recent colonoscopy showed no problems, 2 polyps..non cancerous. Gastro did not give me "diagnosis" other than "IBS" and said "more fiber, water"..which I have already tried in just about every food and fiber supplement, but Fiber does not work for me. I drink lots of water, exercise 5 days a week. He put me on Linzess 290 and it was a disaster. I have to go to Mandatory groups, and I was having loose stools all day. If we miss groups 5 times, we lose our housing. (I live in a home where people are on SSDI disability)..rent is subsidized, but lots of rules and have to attend groups. Gastro never available when I called with questions..co-pay too high to make office visits with him..which he probably would have dismissed me again. Nurses never knew answers when I called in, about adding digestive enzyme or magnesium to help. They would always have to page him at hospital and said they would get back to me by end of day which they never did. Found another Gastro and went to him last week and he was worse than the first one. He has just one nurse who is very rude on phone. He put me on Linzess even though I told him it did not help. He said try again, and to break the capsule open and Put the contents in water..so now looking for another Gastro..I don't know what to do. Tired of getting dismissed, ignored, being rude too, uncaring nurses, gastros, etc. Just wondering if anyone on Linzess and if any success. Thanks for reading.