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Zytiga
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Changing from Adenocarcinoma to small cells or Neuroendocrine?
He’s taken
Zytiga
since 10 Mar 2021 with PSA at around 4 and it continuously increased until this weird thing happened.
He’s taken
Zytiga
since 10 Mar 2021 with PSA at around 4 and it continuously increased until this weird thing happened.
Hidden
in
Advanced Prostate Cancer
2 years ago
Lutetium-617 vs Lutetium-TLX591 plus Xyandi after Zytiga failure. Question from Australia.
PSA doubling every 4 weeks following failure of
Zytiga
. Now 1.7. Mets in pelvis, scapula and L5. Previous Docetaxel, EBRT and Stereotactic. 68 yrs old hoping to make it to 70. Any suggestions, information or questions greatly appreciated. Mark Emrys
PSA doubling every 4 weeks following failure of
Zytiga
. Now 1.7. Mets in pelvis, scapula and L5. Previous Docetaxel, EBRT and Stereotactic. 68 yrs old hoping to make it to 70. Any suggestions, information or questions greatly appreciated. Mark Emrys
MarkEmrys
in
Advanced Prostate Cancer
3 years ago
Why would PSA drop now?
When Jeff was in between Docetaxel failing and his actively starting
Zytiga
, his PSA dropped. Now, Jeff is in between carboplatin/cabazitaxel failing and who knows what’s next and his PSA dropped from 365 to 275. I’m baffled. Twice now in between treatments, his PSA has dropped.
When Jeff was in between Docetaxel failing and his actively starting
Zytiga
, his PSA dropped. Now, Jeff is in between carboplatin/cabazitaxel failing and who knows what’s next and his PSA dropped from 365 to 275. I’m baffled. Twice now in between treatments, his PSA has dropped.
Pancake_Lefse
in
Advanced Prostate Cancer
2 years ago
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Blood pressure, abiraterone, prednisone, and eplerenone update
Average BP in early 2019 = 142/64 Feb 2021 – Prednisone reduced to 5 mg following clearer reading of
Zytiga
guidelines. BP increase accelerated. Late 2021 through early 2022 – BP average = 167/80 Jan 27, 2021 – Prednisone increased to 10 mg to address BP Feb 11, 2022 – Negligible BP change.
Average BP in early 2019 = 142/64 Feb 2021 – Prednisone reduced to 5 mg following clearer reading of
Zytiga
guidelines. BP increase accelerated. Late 2021 through early 2022 – BP average = 167/80 Jan 27, 2021 – Prednisone increased to 10 mg to address BP Feb 11, 2022 – Negligible BP change.
Gearhead
in
Advanced Prostate Cancer
2 years ago
Lymphocytes & Absolute Lymphocytes
....... 8-37 ALT-(Sgpt) 24-----8-35 Alkaline Phosphate -56.........50-150 Albumin-4.6......3.5-............3.5-5.0 Bilirubin---.8-------0.1-1.0 Lymphocytes--6%-------16-47 % Very low Absolute Lymphocytes -----.33------0.9-3.30 Very low PSA --.04 down from .22 6 month Eligard in Dec. 21 Started
Zytiga
....... 8-37 ALT-(Sgpt) 24-----8-35 Alkaline Phosphate -56.........50-150 Albumin-4.6......3.5-............3.5-5.0 Bilirubin---.8-------0.1-1.0 Lymphocytes--6%-------16-47 % Very low Absolute Lymphocytes -----.33------0.9-3.30 Very low PSA --.04 down from .22 6 month Eligard in Dec. 21 Started
Zytiga
reconjj
in
Advanced Prostate Cancer
3 years ago
Abiraterone slowing down question.
When
Zytiga
stops working, does that mean you are Castrative Resistant?
When
Zytiga
stops working, does that mean you are Castrative Resistant?
JamesHughs
in
Advanced Prostate Cancer
3 years ago
Here we go again….
He added
Zytiga
in 2019 (PSA had gone back to 11) Recommendation now to re-do taxotere series (x 10 vs past x 6 doses), then add xtandi as follow-up….continuing lupron,
Zytiga
, too. Going to do some blood testing for genetic markers, etc.
He added
Zytiga
in 2019 (PSA had gone back to 11) Recommendation now to re-do taxotere series (x 10 vs past x 6 doses), then add xtandi as follow-up….continuing lupron,
Zytiga
, too. Going to do some blood testing for genetic markers, etc.
Cateydid
in
Advanced Prostate Cancer
3 years ago
Update, diagnosed 12/26/2018
July 16, 2020 started
zytiga
and an appointment with radiologists, oncology, today after bone scan last week. On diagnosis had 5 bone mets. Went away with treatment I've listed. Current bone scan 2 weeks ago showed uptake to left lower trocanter and left numeral head.
July 16, 2020 started
zytiga
and an appointment with radiologists, oncology, today after bone scan last week. On diagnosis had 5 bone mets. Went away with treatment I've listed. Current bone scan 2 weeks ago showed uptake to left lower trocanter and left numeral head.
Altamonttt
in
Advanced Prostate Cancer
3 years ago
Benefit of "triplet therapy" confirmed with enzalutamide too
www.urotoday.com/conference-highlights/asco-2022/asco-2022-prostate-cancer/137646-asco-2022-updated-overall-survival-outcomes-in-enzamet-anzup-1304-an-international-cooperative-group-trial-of-enzalutamide-in-metastatic-hormone-sensitive-prostate-cancer-mhspc.html Enzalutamide (Xtandi) joins abiraterone (
Zytiga
www.urotoday.com/conference-highlights/asco-2022/asco-2022-prostate-cancer/137646-asco-2022-updated-overall-survival-outcomes-in-enzamet-anzup-1304-an-international-cooperative-group-trial-of-enzalutamide-in-metastatic-hormone-sensitive-prostate-cancer-mhspc.html Enzalutamide (Xtandi) joins abiraterone (
Zytiga
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
Latest from BATman Denmeade
The duration of response to Xtandi or
Zytiga
after BAT in this small study was about 25 months.
The duration of response to Xtandi or
Zytiga
after BAT in this small study was about 25 months.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Resistant to Zytiga, Xtandi and Chemo? Here is a promising trial.
This trial tested the new drug ODM-208 which can be effective after
Zytiga
, Xtandi and Chemo have failed. Here are the details of this study, which is currently recruting: https://clinicaltrials.gov/ct2/show/NCT03436485 And here is a video with Dr.
This trial tested the new drug ODM-208 which can be effective after
Zytiga
, Xtandi and Chemo have failed. Here are the details of this study, which is currently recruting: https://clinicaltrials.gov/ct2/show/NCT03436485 And here is a video with Dr.
GP24
in
Advanced Prostate Cancer
3 years ago
$Zytiga/Abiriterone$
Previously switched
ZYTIGA
from CVS Specialty at $366/mo to Walmart Pharm w “GOOD Rx” at $222/mo. Just went in to pick up 3rd month and was told $8,000/mo. WHAT!!🤑. GOOD Rx app says Publix Grocery Pharm at $258/mo. Switched over for pick up tomorrow. Phew.
Previously switched
ZYTIGA
from CVS Specialty at $366/mo to Walmart Pharm w “GOOD Rx” at $222/mo. Just went in to pick up 3rd month and was told $8,000/mo. WHAT!!🤑. GOOD Rx app says Publix Grocery Pharm at $258/mo. Switched over for pick up tomorrow. Phew.
Spyder54
in
Advanced Prostate Cancer
3 years ago
In rare flop, Merck calls it quits on Keytruda-Lynparza combo in prostate cancer
Compared with either Johnson & Johnson’s
Zytiga
or Astellas and Pfizer’s Xtandi, the Keytruda-Lynparza combo failed to further extend patients’ lives, nor did it stall tumor progression. All patients had prior chemo treatment and one of the two hormone therapies.
Compared with either Johnson & Johnson’s
Zytiga
or Astellas and Pfizer’s Xtandi, the Keytruda-Lynparza combo failed to further extend patients’ lives, nor did it stall tumor progression. All patients had prior chemo treatment and one of the two hormone therapies.
fmenninger
in
Advanced Prostate Cancer
3 years ago
Zytiga with breakfast?
Hi everyone, please could someone guide me on whether they take a lower dose of
Zytiga
with breakfast? If yes, do you take a low-fat or a high-fat breakfast?
Hi everyone, please could someone guide me on whether they take a lower dose of
Zytiga
with breakfast? If yes, do you take a low-fat or a high-fat breakfast?
Rodeoz15
in
Advanced Prostate Cancer
3 years ago
Chemo
He has been on
Zytiga
, Lynparza, Keytruda now the chemo. Just asking opinions. Do any of you think that maybe Xtandi could work? Could Darolutamide also be a possibility or is this drug only used with no Mets? He has to wait a couple more months for any trial due to blood clots.
He has been on
Zytiga
, Lynparza, Keytruda now the chemo. Just asking opinions. Do any of you think that maybe Xtandi could work? Could Darolutamide also be a possibility or is this drug only used with no Mets? He has to wait a couple more months for any trial due to blood clots.
Fight11
in
Advanced Prostate Cancer
3 years ago
Zytiga vs Xtandi
One oncologist likes
Zytiga
over Xtandi and the other one likes Xtandi over
Zytiga
. I do have HBP, currently well controlled avg 117/74 and diabetes 2, recently dropped A1C from 8.4 to 6.6 with diet & exercise + metformin 500 twice a day. History of arrhythmia/AFib with mother and uncle.
One oncologist likes
Zytiga
over Xtandi and the other one likes Xtandi over
Zytiga
. I do have HBP, currently well controlled avg 117/74 and diabetes 2, recently dropped A1C from 8.4 to 6.6 with diet & exercise + metformin 500 twice a day. History of arrhythmia/AFib with mother and uncle.
TnRebel62
in
Advanced Prostate Cancer
3 years ago
PSA up after one month on Xtandi
My husband has been taking
Zytiga
, Lupron, Xgeva and prednisone for two years. The combination worked well with only a few side effects (fatigue and hot flashes), and his PSA became undectable within a few months.
My husband has been taking
Zytiga
, Lupron, Xgeva and prednisone for two years. The combination worked well with only a few side effects (fatigue and hot flashes), and his PSA became undectable within a few months.
dico
in
Advanced Prostate Cancer
3 years ago
Treatment Decision
Would there be any benefit from aggressive treatment adding
Zytiga
/Apalutamide? I would appreciate any other suggestions. Radiation treatment for the newly found suspicious retrocaval node may not do much good. Because there could other smaller metastasis undetectable by CT scan.
Would there be any benefit from aggressive treatment adding
Zytiga
/Apalutamide? I would appreciate any other suggestions. Radiation treatment for the newly found suspicious retrocaval node may not do much good. Because there could other smaller metastasis undetectable by CT scan.
dac500
in
Advanced Prostate Cancer
2 years ago
Next Move
I've been on Lupron,
Zytiga
, Prednisone for 3 years now and it appears that it has run it's course. I am grateful that it has worked for this long, but it appears I will be needing to make a move to the next therapy.
I've been on Lupron,
Zytiga
, Prednisone for 3 years now and it appears that it has run it's course. I am grateful that it has worked for this long, but it appears I will be needing to make a move to the next therapy.
Kentucky1
in
Advanced Prostate Cancer
3 years ago
My dad’s test result :(
First, a short background of my dad (72 years old) was diagnosed with G9 metastatic prostate cancer in early 2020, first step was radiation and then ADT +
Zytiga
, PSA dropped to 0.01 and OC recommended a vacation! 5 months later, in early March his PSA level increased to 0.04 !
First, a short background of my dad (72 years old) was diagnosed with G9 metastatic prostate cancer in early 2020, first step was radiation and then ADT +
Zytiga
, PSA dropped to 0.01 and OC recommended a vacation! 5 months later, in early March his PSA level increased to 0.04 !
Spring_moon
in
Advanced Prostate Cancer
3 years ago
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