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Yervoy
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FDA Approves nivolumab Plus ipilimumab and Chemotherapy for First-Line Treatment of Metastatic NSCLC
The combination of Opdivo,
Yervoy
, and chemotherapy being available as a first line targeted therapy option gives patients more options for first line treatment. Patients are also able to stop chemotherapy after the two cycles and continue with the combination of Opdivo and
Yervoy
.
The combination of Opdivo,
Yervoy
, and chemotherapy being available as a first line targeted therapy option gives patients more options for first line treatment. Patients are also able to stop chemotherapy after the two cycles and continue with the combination of Opdivo and
Yervoy
.
Miranda_GO2
Administrator
in
Lung Cancer Support
4 years ago
Opdivo and Yervoy combination approved for Non-small cell lung cancer
The approval of Opdivo (nivolumab) and
Yervoy
(ipilimumab) marks the first approval of combined immunotherapy treatment for NSCLC. This gives patients whose cancer does not have a targetable change a new avenue for treatment and more options than they have ever had.
The approval of Opdivo (nivolumab) and
Yervoy
(ipilimumab) marks the first approval of combined immunotherapy treatment for NSCLC. This gives patients whose cancer does not have a targetable change a new avenue for treatment and more options than they have ever had.
Miranda_GO2
Administrator
in
Lung Cancer Support
4 years ago
Is this the end
His doctor says the “plan” is to give another cycle of the
yervoy
/ nivo combo on 4/21. I’m not sure Mike will make it till then. The doctor gives me no ideas about if this is the end or not. I’m lost...
His doctor says the “plan” is to give another cycle of the
yervoy
/ nivo combo on 4/21. I’m not sure Mike will make it till then. The doctor gives me no ideas about if this is the end or not. I’m lost...
Blair77
in
Advanced Prostate Cancer
4 years ago
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Latest results from MDA immunotherapy. trial for mCRPC using ipilimumab. MedPageToday & Science Translational Medicine - April 2020
[/i] [i]Six of nine patients whose tumors had favorable characteristics -- defined by pretreatment levels of two immune-cell parameters and/or robust antigen-specific T-cell responses -- remained alive 33 to 54 months after treatment with ipilimumab (
Yervoy
).
[/i] [i]Six of nine patients whose tumors had favorable characteristics -- defined by pretreatment levels of two immune-cell parameters and/or robust antigen-specific T-cell responses -- remained alive 33 to 54 months after treatment with ipilimumab (
Yervoy
).
cujoe
in
Fight Prostate Cancer
4 years ago
Next step in treatment or no changes yet?
I was up for the
Yervoy
in Dynamo trial in 2016 but after Provenge my psa lowered. If its time for more treatment I would like to find the trial that currently offers the most promise. Any good ideas? Larry Dx 3/15 in Tulsa.
I was up for the
Yervoy
in Dynamo trial in 2016 but after Provenge my psa lowered. If its time for more treatment I would like to find the trial that currently offers the most promise. Any good ideas? Larry Dx 3/15 in Tulsa.
math33
in
Advanced Prostate Cancer
4 years ago
People of HealthUnlocked | Meet Ryan
I got chosen for what later turned out to be the FDA approved dose of what is now commercially called
Yervoy
. I finished each dose with no side effects. I continued to have scans as scheduled, and I continued to abuse drugs.
I got chosen for what later turned out to be the FDA approved dose of what is now commercially called
Yervoy
. I finished each dose with no side effects. I continued to have scans as scheduled, and I continued to abuse drugs.
MarketingHU
in
HealthUnlocked Blog
4 years ago
mesothelioma - anyone tried Opdivo or Yervoy?
I read about Opdivo/
Yervoy
immune therapy (I believe nivolumab and ipilimumab are the exact drug names), could anyone share his experience? Do you think giving him intravenous injections of glucose, vitamins, protein solutions could improve his general condition?
I read about Opdivo/
Yervoy
immune therapy (I believe nivolumab and ipilimumab are the exact drug names), could anyone share his experience? Do you think giving him intravenous injections of glucose, vitamins, protein solutions could improve his general condition?
zazi717
in
Lung Conditions Community Forum
5 years ago
Sadly, TIL Trial has ended for my husband
Our VCU doc did mention NIVO as a possibility, but Wayne has already had Keytruda and
Yervoy
, and TIL as immunotherapies, so the doc will need to explain to me what the last immunotherapy has that the others have not.
Our VCU doc did mention NIVO as a possibility, but Wayne has already had Keytruda and
Yervoy
, and TIL as immunotherapies, so the doc will need to explain to me what the last immunotherapy has that the others have not.
missyrand
Ambassador
in
Melanoma Caregivers
5 years ago
Antitumor Activity Seen With Keytruda in mCRPC
Other studies involving PD-1 inhibitor-based combination regimens have shown activity in mCRPC, including the CheckMate 650 trial of nivolumab (Opdivo) plus the CTLA-4 checkpoint inhibitor ipilimumab (
Yervoy
) and KEYNOTE-365, which showed promising antitumor activity and well-tolerated TRAEs when pembrolizumab
Other studies involving PD-1 inhibitor-based combination regimens have shown activity in mCRPC, including the CheckMate 650 trial of nivolumab (Opdivo) plus the CTLA-4 checkpoint inhibitor ipilimumab (
Yervoy
) and KEYNOTE-365, which showed promising antitumor activity and well-tolerated TRAEs when pembrolizumab
snoraste
in
Advanced Prostate Cancer
4 years ago
What is the Current Status of Yervoy (Ipilimumab)?
What is the Current Status of
Yervoy
(Ipilimumab)? When does it become available? What does it's effectiveness on prostate cancer look like?
What is the Current Status of
Yervoy
(Ipilimumab)? When does it become available? What does it's effectiveness on prostate cancer look like?
cesanon
in
Advanced Prostate Cancer
5 years ago
Immunotherapy
The
yervoy
opdivo combo has knocked a lot of people on their ass (excuse my language).. and some gnarly side effects came with it. Some couldn’t finish the 4 doses where it was combined. Afraid that if we let the guard down medication wise that we could go through a “storm” again.. just praying.
The
yervoy
opdivo combo has knocked a lot of people on their ass (excuse my language).. and some gnarly side effects came with it. Some couldn’t finish the 4 doses where it was combined. Afraid that if we let the guard down medication wise that we could go through a “storm” again.. just praying.
kellyOd
in
Melanoma Caregivers
5 years ago
Need advice!!!
So Ryan’s oncologist just called and said that the
Yervoy
Keytruda combo is being switched to
Yervoy
Opdivo combo and I’m fuming. I’m pretty sure she said that it was changed because of an insurance issue and I need advice on what to do. Should I fight for the
Yervoy
keytruda combo?
So Ryan’s oncologist just called and said that the
Yervoy
Keytruda combo is being switched to
Yervoy
Opdivo combo and I’m fuming. I’m pretty sure she said that it was changed because of an insurance issue and I need advice on what to do. Should I fight for the
Yervoy
keytruda combo?
kellyOd
in
Melanoma Caregivers
5 years ago
Immunotherapy for prostate cancer continues to disappoint, but at least we are learning why
I've updated this article about the importance of timing in prostate cancer therapies with the early results of the "CHECKMATE 650" clinical trial that combined nivolumab (Opdivo) and ipilimumab (
Yervoy
).
I've updated this article about the importance of timing in prostate cancer therapies with the early results of the "CHECKMATE 650" clinical trial that combined nivolumab (Opdivo) and ipilimumab (
Yervoy
).
Tall_Allen
in
Advanced Prostate Cancer
5 years ago
PET scan update
The clean PET scan means we can now make a safe move to the
yervoy
opdivo combo; with a clean slate. So if anything shows up we know it’s because the combo isn’t working. It’s a beautiful base to start with.
The clean PET scan means we can now make a safe move to the
yervoy
opdivo combo; with a clean slate. So if anything shows up we know it’s because the combo isn’t working. It’s a beautiful base to start with.
kellyOd
in
Melanoma Caregivers
5 years ago
Combination of two immunotherapy drugs, showing positive results on patients with no treatments left and cancer spreading (not a false hope)
Drugs are
Yervoy
and Opdivo. https://www.houstonchronicle.com/news/houston-texas/houston/article/Combination-immunotherapy-promising-in-prostate-13621268.php Bob
Drugs are
Yervoy
and Opdivo. https://www.houstonchronicle.com/news/houston-texas/houston/article/Combination-immunotherapy-promising-in-prostate-13621268.php Bob
bboby
in
Advanced Prostate Cancer
5 years ago
Opdivo-Yervoy Combo Shows Signs of Activity in CRPC Patients with Metastases
Much like we have seen in HIV. https://prostatecancernewstoday.com/2019/03/06/opdivo-
yervoy
-combo-shows-promise-in-crpc-patients-with-metastases/?utm_medium=desktop-push-notification&utm_source=Notifications&utm_campaign=OneSignal
Much like we have seen in HIV. https://prostatecancernewstoday.com/2019/03/06/opdivo-
yervoy
-combo-shows-promise-in-crpc-patients-with-metastases/?utm_medium=desktop-push-notification&utm_source=Notifications&utm_campaign=OneSignal
Moespy
in
Advanced Prostate Cancer
5 years ago
ER trip this morning ends with no clear etiology
More likely to be side effect from the
Yervoy
treatment from the fall. Cold compress and anti inflammatory meds til Tuesday, then discontinue because of colonoscopy 2/13 scheduled.
More likely to be side effect from the
Yervoy
treatment from the fall. Cold compress and anti inflammatory meds til Tuesday, then discontinue because of colonoscopy 2/13 scheduled.
missyrand
Ambassador
in
Melanoma Caregivers
5 years ago
immunotherapy combo worked in 25% of asymptomatic and minimally symptomatic patients who progressed after second-generation hormonal therapy
Really good news: The combination of nivolumab (Opdivo) plus ipilimumab (
Yervoy
) demonstrated activity in a biomarker-enriched population of patients with metastatic castration-resistant prostate cancer (mCRPC); however, researchers need to refine the toxicity profile, said Sumit K.
Really good news: The combination of nivolumab (Opdivo) plus ipilimumab (
Yervoy
) demonstrated activity in a biomarker-enriched population of patients with metastatic castration-resistant prostate cancer (mCRPC); however, researchers need to refine the toxicity profile, said Sumit K.
George71
in
Advanced Prostate Cancer
5 years ago
My Experience With Melanoma
I got chosen for what later turned out to be the FDA approved dose of what is now commercially called
Yervoy
. I finished each dose with no side effects. I continued to have scans as scheduled, and I continued to abuse drugs.
I got chosen for what later turned out to be the FDA approved dose of what is now commercially called
Yervoy
. I finished each dose with no side effects. I continued to have scans as scheduled, and I continued to abuse drugs.
Ryan2
in
Young Adults with Melanoma
5 years ago
Still trucking
He is going to be switched in a few months from the Taf/Mek combo to Keytruda, with 4 sessions of
Yervoy
so long as we don’t go through a huge “storm” again.. other than that Ryan went from 184lbs when he was healthy before the cancer diagnosis, down to 170lbs, back up to 191lbs :) he’s not happy about
He is going to be switched in a few months from the Taf/Mek combo to Keytruda, with 4 sessions of
Yervoy
so long as we don’t go through a huge “storm” again.. other than that Ryan went from 184lbs when he was healthy before the cancer diagnosis, down to 170lbs, back up to 191lbs :) he’s not happy about
kellyOd
in
Melanoma Caregivers
5 years ago
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