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Darolutamide (Nubeqa) Vs Enzalutamide ( Xtandi)
Are there any studies comparing efficacy and side effect profile of darolutamide Vs enzalutamide when given together with first generation ADT ? I read that darolutamide does not cross blood brain barrier so may have lesser side effects ?
Are there any studies comparing efficacy and side effect profile of darolutamide Vs enzalutamide when given together with first generation ADT ? I read that darolutamide does not cross blood brain barrier so may have lesser side effects ?
Tinkudi
in
Advanced Prostate Cancer
3 months ago
New to Medicare
Does Medicare part B and D cover all the major PC drug treatments with a minimal co-pay and minimal approvals i.e.Taxotere, Erleada,
Xtandi
, Pluvicto (Lu177), Dapolutamide, AC 225 etc. Also are PSMA scans covered?Thanks for your help.
Does Medicare part B and D cover all the major PC drug treatments with a minimal co-pay and minimal approvals i.e.Taxotere, Erleada,
Xtandi
, Pluvicto (Lu177), Dapolutamide, AC 225 etc. Also are PSMA scans covered?Thanks for your help.
Lefty26
in
Advanced Prostate Cancer
1 year ago
prostate metastasis
He’s been having Eligard stomach infusions and
Xtandi
prescription daily along with taking Calcium prescription ….. he did have 5 intense rounds of Radiation on his upper spine, C 1 - C2 - C-3 and one shoulder area ….. my question is, he had a repeat of both of the Nuclear Bone Scans - just like 2 weeks
He’s been having Eligard stomach infusions and
Xtandi
prescription daily along with taking Calcium prescription ….. he did have 5 intense rounds of Radiation on his upper spine, C 1 - C2 - C-3 and one shoulder area ….. my question is, he had a repeat of both of the Nuclear Bone Scans - just like 2 weeks
Myshadowgirl1
in
Advanced Prostate Cancer
11 months ago
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BAT trial
With
Xtandi
failing and my metastasizes not PSMA avid enough for Lutetium my MO referred me to the Kinghorn Cancer Centre in Sydney to be assessed for a clinical trial involving BAT and Carboplatin (chemo).
With
Xtandi
failing and my metastasizes not PSMA avid enough for Lutetium my MO referred me to the Kinghorn Cancer Centre in Sydney to be assessed for a clinical trial involving BAT and Carboplatin (chemo).
Bjry
in
Advanced Prostate Cancer
1 year ago
Radium-223 + Xtandi?
When asked if I should stay on
Xtandi
, both my MOs said it’s ok to continue and pretty much left it up to me as there’s no indication it’s affective since PSA is rising. Any thoughts on staying on
Xtandi
in which case treatment would be: Radium-223, Lupron,
Xtandi
, Zometa.
When asked if I should stay on
Xtandi
, both my MOs said it’s ok to continue and pretty much left it up to me as there’s no indication it’s affective since PSA is rising. Any thoughts on staying on
Xtandi
in which case treatment would be: Radium-223, Lupron,
Xtandi
, Zometa.
MechD
in
Advanced Prostate Cancer
1 year ago
Anyone here? switched to Nubeqa from Xtandi
I wanted to know if anyone here in this group tried
Xtandi
which stopped responding after few months and switched to Nubeqa and it worked and showed success.
I wanted to know if anyone here in this group tried
Xtandi
which stopped responding after few months and switched to Nubeqa and it worked and showed success.
God_Loves_Me
in
Advanced Prostate Cancer
8 months ago
Enzalutamide any advice/tips for dealing with side effects
Now doctors are suggesting that possible option is to switch onto
Xtandi
/Enzalutamide. Anyone in the same or similar situation. What are the main side effects of Enzalutamide and does anyone have advice or tips with dealing with side effects of this drug. Any advice would be much appreciated.
Now doctors are suggesting that possible option is to switch onto
Xtandi
/Enzalutamide. Anyone in the same or similar situation. What are the main side effects of Enzalutamide and does anyone have advice or tips with dealing with side effects of this drug. Any advice would be much appreciated.
Ronnie7C
in
Advanced Prostate Cancer
1 year ago
Pluvicto+Xtandi Delays Progression Better than Xtandi-alone in mCRPC
Significant improvement in progression-free survival, PSA, and pain scores. Side effects were fatigue, nausea and dry mouth. https://www.prostatecancer.news/2024/04/pluvictoxtandi-delays-progression.html
Significant improvement in progression-free survival, PSA, and pain scores. Side effects were fatigue, nausea and dry mouth. https://www.prostatecancer.news/2024/04/pluvictoxtandi-delays-progression.html
Tall_Allen
in
Advanced Prostate Cancer
6 months ago
BAT Patient Guide
"A larger randomized study comparing overall patient survival following treatment with sequential BAT →
Xtandi
versus enzalutamide or chemotherapy alone will be required to obtain FDA approval of this approach.
"A larger randomized study comparing overall patient survival following treatment with sequential BAT →
Xtandi
versus enzalutamide or chemotherapy alone will be required to obtain FDA approval of this approach.
dhccpa
in
Advanced Prostate Cancer
1 year ago
Second Opinion
I started Eligard injections and
Xtandi
. However, I had a number of cardiac events including a mild heart attack and went off the
Xtandi
for 9 months. After consulting with my cardiologist and a cardiologist oncologist, they ensure that none ADT drugs would have my heart in excellent shape.
I started Eligard injections and
Xtandi
. However, I had a number of cardiac events including a mild heart attack and went off the
Xtandi
for 9 months. After consulting with my cardiologist and a cardiologist oncologist, they ensure that none ADT drugs would have my heart in excellent shape.
jcarey79
in
Advanced Prostate Cancer
1 year ago
Update on 8/4 post from alperk
Conversely I am reluctant to move to
Xtandi
since all other cancer sites are responding to Zytiga. Looking for advice.
Conversely I am reluctant to move to
Xtandi
since all other cancer sites are responding to Zytiga. Looking for advice.
alperk
in
Advanced Prostate Cancer
1 year ago
FDG+/PSMA- lesions
Xtandi
failed, but at the moment he is still on it as we evaluate possible treatment options.
Xtandi
failed, but at the moment he is still on it as we evaluate possible treatment options.
MyDad76
in
Advanced Prostate Cancer
1 year ago
What Next After Xtandi Fail?
On Lupron from the beginning and
Xtandi
since Nov 2019. Hit Nadir of .21 in Dec 2022. Since then, PSA has been jumping around, but trending upward. End of 2023, it was at .67. Feb 2024, PSA up to .87. Yesterday, it was 1.16. Have Oncology appointment tomorrow. Time to talk what comes next.
On Lupron from the beginning and
Xtandi
since Nov 2019. Hit Nadir of .21 in Dec 2022. Since then, PSA has been jumping around, but trending upward. End of 2023, it was at .67. Feb 2024, PSA up to .87. Yesterday, it was 1.16. Have Oncology appointment tomorrow. Time to talk what comes next.
ppulatie
in
Advanced Prostate Cancer
4 months ago
Xtandi Pricing
This is an interesting article that talks about the excessive pricing of
Xtandi
to the US. https://www.statnews.com/2022/01/03/march-in-rights-protect-prostate-cancer-patients-from-excessive-drug-prices/
This is an interesting article that talks about the excessive pricing of
Xtandi
to the US. https://www.statnews.com/2022/01/03/march-in-rights-protect-prostate-cancer-patients-from-excessive-drug-prices/
Cyclingrealtor
in
Advanced Prostate Cancer
9 months ago
Surgery While on Xtandi/Eligard
Do i stop
xtandi
for a week or two whilst i heal from the partial nephrectomy? Anyone with similar experience? I would think that the two drs would coordinate (same hospital) but they seemingly don’t.
Do i stop
xtandi
for a week or two whilst i heal from the partial nephrectomy? Anyone with similar experience? I would think that the two drs would coordinate (same hospital) but they seemingly don’t.
Hidden
in
Advanced Prostate Cancer
1 year ago
Two trees, four textures; a mixed media painting
On a darker note, I have an appointment with my oncologist on Monday afternoon to discuss whether my
Xtandi
has finally failed me and if we shall be moving to intravenous chemo. She has not disguised the fact that chemo would only be buying me time, and probably less of it that more. Ho hum.
On a darker note, I have an appointment with my oncologist on Monday afternoon to discuss whether my
Xtandi
has finally failed me and if we shall be moving to intravenous chemo. She has not disguised the fact that chemo would only be buying me time, and probably less of it that more. Ho hum.
BrentW
in
Care Community
1 year ago
QoL: Mixed media painting, 'Two trees, four textures'.
On a darker note, I have an appointment with my oncologist on Monday afternoon to discuss whether my
Xtandi
has finally failed me and if we shall be moving to intravenous chemo. She has not disguised the fact that chemo would only be buying me time, and probably less of it that more. Ho hum.
On a darker note, I have an appointment with my oncologist on Monday afternoon to discuss whether my
Xtandi
has finally failed me and if we shall be moving to intravenous chemo. She has not disguised the fact that chemo would only be buying me time, and probably less of it that more. Ho hum.
BrentW
in
Advanced Prostate Cancer
1 year ago
blood in urine
feel great but I detected blood in my urine what does mean … only other time was after biopsy… on lupron and
xtandi
just over two years and radiation to debulk prostate
feel great but I detected blood in my urine what does mean … only other time was after biopsy… on lupron and
xtandi
just over two years and radiation to debulk prostate
rogerandme
in
Advanced Prostate Cancer
1 year ago
Talzenna
His oncologist said give the combo of
Xtandi
and Talzenna at least 6-8 weeks to see results. Any info is appreciated. My dad is a strong 87 yo that really hasn’t stopped doing what he wants/can. Diagnosed a little over 3 years ago Gleason score of 9 with bone mets.
His oncologist said give the combo of
Xtandi
and Talzenna at least 6-8 weeks to see results. Any info is appreciated. My dad is a strong 87 yo that really hasn’t stopped doing what he wants/can. Diagnosed a little over 3 years ago Gleason score of 9 with bone mets.
Mikerest
in
Advanced Prostate Cancer
1 year ago
Long survivors with ADT + Xtandi (Enzulatamide)
I am advised to start ADT +
Xtandi
. Who are longest still on this combination without getting castration resistant?
I am advised to start ADT +
Xtandi
. Who are longest still on this combination without getting castration resistant?
ElemanJ
in
Advanced Prostate Cancer
1 year ago
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