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Experiences with
Sirolimus
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Treatments for C3G
These drugs include: o Glucocorticoids (corticosteroids, steroids) o Rituximab o Cyclophosphamide o Mycophenolate mofetil (MMF) o Tacrolimus o
Sirolimus
o Azathioprine
• Plasma exchange (plasmapheresis):
Plasma
These drugs include: o Glucocorticoids (corticosteroids, steroids) o Rituximab o Cyclophosphamide o Mycophenolate mofetil (MMF) o Tacrolimus o
Sirolimus
o Azathioprine
• Plasma exchange (plasmapheresis):
Plasma
DavidF_NKF
Administrator
in
C3 Glomerulopathy
5 years ago
Metformin wonder drug?
Br J Clin Pharmacol. 2018 Oct 5. doi: 10.1111/bcp.13780. [Epub ahead of print] The journey of metformin from glycaemic control to mTOR inhibition and the suppression of tumour growth. Amin S1, Lux A1, O'Callaghan F2. Author information Abstract Our knowledge of the effect of metformin on human health
Br J Clin Pharmacol. 2018 Oct 5. doi: 10.1111/bcp.13780. [Epub ahead of print] The journey of metformin from glycaemic control to mTOR inhibition and the suppression of tumour growth. Amin S1, Lux A1, O'Callaghan F2. Author information Abstract Our knowledge of the effect of metformin on human health
Graham49
in
Advanced Prostate Cancer
5 years ago
LAM news 2.
The others are more technical about
Sirolimus
and medications on trials. Hope it helps. Fran xx https://www.thelamfoundation.org/Newly-Diagnosed/Learning-About-Lam/About-LAM
The others are more technical about
Sirolimus
and medications on trials. Hope it helps. Fran xx https://www.thelamfoundation.org/Newly-Diagnosed/Learning-About-Lam/About-LAM
Hidden
in
Lung Conditions Community Forum
6 years ago
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Sirolimus used for LAM, but not only
Well Metformin Rapamycin, Resveratrol are the new better-aging pharma trends..So they are selling those to people who want to rejuvenate. I don’t know honestly..In Swiss clinics they go like hot cakes..as well as stem cells. I am old-fashioned maybe but meds are meds, and they are for treatment ..
Well Metformin Rapamycin, Resveratrol are the new better-aging pharma trends..So they are selling those to people who want to rejuvenate. I don’t know honestly..In Swiss clinics they go like hot cakes..as well as stem cells. I am old-fashioned maybe but meds are meds, and they are for treatment ..
Hidden
in
Lung Conditions Community Forum
6 years ago
News and thoughts..
I must tell my LAM Sis 🌸 reading this that I am not on
Sirolimus
so it can’t be that and I don’t want you to worry, we all react differently.
I must tell my LAM Sis 🌸 reading this that I am not on
Sirolimus
so it can’t be that and I don’t want you to worry, we all react differently.
Hidden
in
Lung Conditions Community Forum
6 years ago
Vitamin D research
LAM action found that that Vit D protein is 2/3 lower in LAM patients. So they also measured Vit D levels in blood and found they were lower than normal. All that improved with Rapamycin I must say in my case my Vegf-d ( LAM bio marker) is lower since I have started on Vit D and I am not on Rapamycin
LAM action found that that Vit D protein is 2/3 lower in LAM patients. So they also measured Vit D levels in blood and found they were lower than normal. All that improved with Rapamycin I must say in my case my Vegf-d ( LAM bio marker) is lower since I have started on Vit D and I am not on Rapamycin
Hidden
in
Lung Conditions Community Forum
6 years ago
Switching to Prograf
I am switching from
Sirolimus
to Prograf because of a surgical procedure.
Sirolimus
delays healing. Any one have issues with side effects from Prograf. I only have one with
Sirolimus
and am concerned. Thanks.
I am switching from
Sirolimus
to Prograf because of a surgical procedure.
Sirolimus
delays healing. Any one have issues with side effects from Prograf. I only have one with
Sirolimus
and am concerned. Thanks.
Transplant37
in
Kidney Transplant
6 years ago
Foods/Supplements-Vitamins: Licorice (Liquorice) (Glycyrrhiza glabra L.).
This post is prompted by a new study [20]. But first a review of PCa literature. {{{For those who want the bottom line: "Our results indicate that administration of DBM and PEITC in combination may be an effective strategy for inhibiting/delaying the progression of prostate cancer to androgen independence
This post is prompted by a new study [20]. But first a review of PCa literature. {{{For those who want the bottom line: "Our results indicate that administration of DBM and PEITC in combination may be an effective strategy for inhibiting/delaying the progression of prostate cancer to androgen independence
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Polyphenols - Inflammation.
Dietary phytochemicals popularly associated with health benefits often have a polyphenolic structure. Polyphenols invariably have an important protective role in plants - e.g. resveratrol, in the skin of red grapes, protects against fungal attack & damage caused by intense sunlight, while sulforaphane
Dietary phytochemicals popularly associated with health benefits often have a polyphenolic structure. Polyphenols invariably have an important protective role in plants - e.g. resveratrol, in the skin of red grapes, protects against fungal attack & damage caused by intense sunlight, while sulforaphane
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Experimental MS Treatment
New gene therapy prevents MS and reverses paralysis in mice MEDICAL Michael IrvingMichael Irving16 hours ago Researchers at the University of Florida have developed a new gene therapy that might help combat... Researchers at the University of Florida have developed a new gene therapy that might help
New gene therapy prevents MS and reverses paralysis in mice MEDICAL Michael IrvingMichael Irving16 hours ago Researchers at the University of Florida have developed a new gene therapy that might help combat... Researchers at the University of Florida have developed a new gene therapy that might help
downrigger
in
My MSAA Community
7 years ago
N-ACETYLCYSTEINE REDUCES LUPUS DISEASE ACTIVITY
I did not stay on it since I am trying natural products first, if that is not possible then I will go straight to
Sirolimus
. BTW, I will be putting up a post also on my short experiment with
Sirolimus
, if anyone is interested in going that route.
I did not stay on it since I am trying natural products first, if that is not possible then I will go straight to
Sirolimus
. BTW, I will be putting up a post also on my short experiment with
Sirolimus
, if anyone is interested in going that route.
RedLizzy
in
LUPUS UK
7 years ago
An Article on Mechanistic target of rapamycin
Here is an article that was posted on wikipedia recently. It is: "[u]Mechanistic target of rapamycin[/u]". It deals with insulin receptors and other issues that go along those lines. Please check out the article at: https://en.m.wikipedia.org/wiki/Mechanistic_target_of_rapamycin
Here is an article that was posted on wikipedia recently. It is: "[u]Mechanistic target of rapamycin[/u]". It deals with insulin receptors and other issues that go along those lines. Please check out the article at: https://en.m.wikipedia.org/wiki/Mechanistic_target_of_rapamycin
Activity2004
Administrator
in
Diabetes India
7 years ago
Foods/Supplements-Vitamins: Cruciferous Phytochemicals - [3] 3,3'-Diindolylmethane [DIM]
DIM (3,3'-Diindolylmethane) is thought to be the most important phytochemical found in broccoli. [1] Estrogen Metabolism. Some may think it odd to begin with estrogen. Much of the DIM literature relates to its effect on estrogen metabolism, & this is of major interest to women with hormonal cancer,
DIM (3,3'-Diindolylmethane) is thought to be the most important phytochemical found in broccoli. [1] Estrogen Metabolism. Some may think it odd to begin with estrogen. Much of the DIM literature relates to its effect on estrogen metabolism, & this is of major interest to women with hormonal cancer,
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Check-up
Should there be a further drop in respiratory functions he would start me on
sirolimus
but there are a lot of bad side effects so they tend to wait..
Should there be a further drop in respiratory functions he would start me on
sirolimus
but there are a lot of bad side effects so they tend to wait..
Hidden
in
Asthma Community Forum
7 years ago
Frustrated
After 3 cycles on a research study which used docetaxel and Carboplatin along with rapamycin taken 2 days before chemo I got mixed results, and have been taken off the study. I continue to feel fine--no pain, plenty of energy, no side effects except numbness in soles of feet and fingertips. PSA came
After 3 cycles on a research study which used docetaxel and Carboplatin along with rapamycin taken 2 days before chemo I got mixed results, and have been taken off the study. I continue to feel fine--no pain, plenty of energy, no side effects except numbness in soles of feet and fingertips. PSA came
Gecrellin
in
Advanced Prostate Cancer
7 years ago
Foods/Supplements-Vitamins: Magnolia - magnolol - honokiol - obovatol - Relora
Timing of this post is due to Gus, who recently posted enthusiastically about honokiol & time to Lupron failure. [1] The following deals with three constituents of the magnolia that have been shown to have anti-tumor effects in PCa: magnolol, honokiol & obovatol. Mention should be made of Relora: "
Timing of this post is due to Gus, who recently posted enthusiastically about honokiol & time to Lupron failure. [1] The following deals with three constituents of the magnolia that have been shown to have anti-tumor effects in PCa: magnolol, honokiol & obovatol. Mention should be made of Relora: "
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Foods/Supplements-Vitamins: Fisetin
[1] In 1995, Edward Giovannucci created the lycopene industry via a Health Professionals Follow-up Study paper [1]: "in 1986, we assessed dietary intake for a 1-year period for a cohort of 47,894 eligible subjects initially free of diagnosed cancer. Follow-up questionnaires were sent to the entire cohort
[1] In 1995, Edward Giovannucci created the lycopene industry via a Health Professionals Follow-up Study paper [1]: "in 1986, we assessed dietary intake for a 1-year period for a cohort of 47,894 eligible subjects initially free of diagnosed cancer. Follow-up questionnaires were sent to the entire cohort
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Foods/Supplements-Vitamins: Fisetin
[1] In 1995, Edward Giovannucci created the lycopene industry via a Health Professionals Follow-up Study paper [1]: "in 1986, we assessed dietary intake for a 1-year period for a cohort of 47,894 eligible subjects initially free of diagnosed cancer. Follow-up questionnaires were sent to the entire cohort
[1] In 1995, Edward Giovannucci created the lycopene industry via a Health Professionals Follow-up Study paper [1]: "in 1986, we assessed dietary intake for a 1-year period for a cohort of 47,894 eligible subjects initially free of diagnosed cancer. Follow-up questionnaires were sent to the entire cohort
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Next steps?
I know my Seattle doc is participating in a trial using docetaxel, Carboplatin and
sirolimus
. The doctor ar Duke mentioned trying oxaliplatin with Gezmar.
I know my Seattle doc is participating in a trial using docetaxel, Carboplatin and
sirolimus
. The doctor ar Duke mentioned trying oxaliplatin with Gezmar.
Gecrellin
in
Advanced Prostate Cancer
8 years ago
Another drug
Temsirolimus, designated Orphan Drug for the treatment of adrenoleukodystrophy CIBERER | Wednesday, June 15, 2016 The European Medicines Agency (EMA) has appointed a molecule, Temsirolimus, as an orphan drug for the treatment of adrenoleukodystrophy, a rare disease neurometabolic origin that affects
Temsirolimus, designated Orphan Drug for the treatment of adrenoleukodystrophy CIBERER | Wednesday, June 15, 2016 The European Medicines Agency (EMA) has appointed a molecule, Temsirolimus, as an orphan drug for the treatment of adrenoleukodystrophy, a rare disease neurometabolic origin that affects
monkeybus
in
AMN EASIER
8 years ago
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