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Australians have your say in getting CLL medicines approved
Venetoclax in combination with
obinutuzumab
for the first-line treatment of patients with chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL) who have coexisting conditions and are unsuitable for fludarabine based chemotherapy 2.
Venetoclax in combination with
obinutuzumab
for the first-line treatment of patients with chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL) who have coexisting conditions and are unsuitable for fludarabine based chemotherapy 2.
lymphomaoz
in
CLL Support
5 years ago
Low LY#?
(PS: before the labs, I ramped-up Venetoclax to 50mg today, & got 1000 of
Obinutuzumab
)
(PS: before the labs, I ramped-up Venetoclax to 50mg today, & got 1000 of
Obinutuzumab
)
DRM18
in
CLL Support
5 years ago
Survey for CLL patients having taken Venetoclax or Acalabrutinib
CLL/SLL Patient Survey If you have CLL or SLL and have been treated with the following therapies, you can help by completing our survey: Venetoclax (Venclexta) +
obinutuzumab
(Gazyva) for first-line treatment of CLL/SLL Acalabrutinib (Calquence) with or without
obinutuzumab
(Gazyva) for first-line
CLL/SLL Patient Survey If you have CLL or SLL and have been treated with the following therapies, you can help by completing our survey: Venetoclax (Venclexta) +
obinutuzumab
(Gazyva) for first-line treatment of CLL/SLL Acalabrutinib (Calquence) with or without
obinutuzumab
(Gazyva) for first-line
cllpag_canada
in
CLL Support
5 years ago
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New Clinical Trail EA9161 with great results!
“A Randomized Phase III Study of the addition of Venetoclax to Ibrutinib and
Obinutuzumab
versus Ibrutinib and
Obinutuzumab
in Untreated Younger Patients with Chronic Lymphocytic Leukemia (CLL)”. I had a new CT scan and bone marrow biopsy the week before I started treatment.
“A Randomized Phase III Study of the addition of Venetoclax to Ibrutinib and
Obinutuzumab
versus Ibrutinib and
Obinutuzumab
in Untreated Younger Patients with Chronic Lymphocytic Leukemia (CLL)”. I had a new CT scan and bone marrow biopsy the week before I started treatment.
Riven8
in
CLL Support
5 years ago
Richter Transformation Testimonials. Survivors
I was on my 6th year of CLL treated with
Obinutuzumab
for 6 months. Six months later diagnosed with RT Large B cell lymphoma.I was treated with 6 treatments of R-chop chemo and 2 pet scans later showed remission.
I was on my 6th year of CLL treated with
Obinutuzumab
for 6 months. Six months later diagnosed with RT Large B cell lymphoma.I was treated with 6 treatments of R-chop chemo and 2 pet scans later showed remission.
Priss69
in
CLL Support
5 years ago
LRA Celebrates Major Research Breakthroughs in 2019
The FDA recently granted
obinutuzumab
Breakthrough Therapy Designation which aims to speed up the development and review of drugs which may demonstrate substantial improvement over available therapy.
The FDA recently granted
obinutuzumab
Breakthrough Therapy Designation which aims to speed up the development and review of drugs which may demonstrate substantial improvement over available therapy.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
5 years ago
LRA Celebrates Major Research Breakthroughs in 2019
The FDA recently granted
obinutuzumab
Breakthrough Therapy Designation which aims to speed up the development and review of drugs which may demonstrate substantial improvement over available therapy.
The FDA recently granted
obinutuzumab
Breakthrough Therapy Designation which aims to speed up the development and review of drugs which may demonstrate substantial improvement over available therapy.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
5 years ago
Debulking Eliminates Need for Hospitalization Prior to Initiating Venetoclax Therapy in untreated CLL pts
Patients with nodes >5 cm treated with
obinutuzumab
or >10 cm treated with
obinutuzumab
plus bendamustine may need >2 cycles to achieve low tumor burden.
Patients with nodes >5 cm treated with
obinutuzumab
or >10 cm treated with
obinutuzumab
plus bendamustine may need >2 cycles to achieve low tumor burden.
Jm954
Administrator
in
CLL Support
5 years ago
News about V+O and Acalabrutinib from EHA
Peter Hillman discusses one of the most promising, Venetoclax and
Obinutuzumab
. See https://cllsociety.org/2019/11/eha-2019-dr-peter-hillman-on-venetoclax-and-
obinutuzumab
-in-cll-chronic-lymphocytic-leukemia/ At EHA 2019, Dr.
Peter Hillman discusses one of the most promising, Venetoclax and
Obinutuzumab
. See https://cllsociety.org/2019/11/eha-2019-dr-peter-hillman-on-venetoclax-and-
obinutuzumab
-in-cll-chronic-lymphocytic-leukemia/ At EHA 2019, Dr.
bkoffman
CLL CURE Hero
in
CLL Support
5 years ago
LRA Shares Excitement For What’s Ahead in Lupus Nephritis
Two new Phase III trials are starting up to test potential treatments – Gazyva® (
obinutuzumab
) and secukinumab. Two potential lupus nephritis treatments – Gazyva and itolizumab – are on an accelerated track for development thanks to special designations by the FDA.
Two new Phase III trials are starting up to test potential treatments – Gazyva® (
obinutuzumab
) and secukinumab. Two potential lupus nephritis treatments – Gazyva and itolizumab – are on an accelerated track for development thanks to special designations by the FDA.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
5 years ago
Symptoms
I will be receiving
Obinutuzumab
and Venetoclax. What are the main symptoms others have experienced? I know what I've been told but wondering what the main ones are I might expect. Also those who have completed this regime, are you in complete remission?
I will be receiving
Obinutuzumab
and Venetoclax. What are the main symptoms others have experienced? I know what I've been told but wondering what the main ones are I might expect. Also those who have completed this regime, are you in complete remission?
booper57
in
CLL Support
5 years ago
Final BMB on AVO Trial Tomorrow
Hi friends, Well, it’s been a great 14 months on the Dana-Farber Acalabrutinib,
Obinutuzumab
, and Venetoclax trial. I’ve been MRD- (blood and marrow) since month 7 and I’m going in tomorrow for my final bone marrow biopsy.
Hi friends, Well, it’s been a great 14 months on the Dana-Farber Acalabrutinib,
Obinutuzumab
, and Venetoclax trial. I’ve been MRD- (blood and marrow) since month 7 and I’m going in tomorrow for my final bone marrow biopsy.
Lily_Pad_Master
in
CLL Support
5 years ago
More ASCO abstracts and our quarterly Newsletter
Watch my review of this research here. https://cllsociety.org/2019/12/asco-2019-dr-koffmans-pick-6-acalabrutinib-with-
obinutuzumab
-for-chronic-lymphocytic-leukemia-cll/ CAR-T therapy has significant side effects and risks, but it knocks back the CLL in most patients.
Watch my review of this research here. https://cllsociety.org/2019/12/asco-2019-dr-koffmans-pick-6-acalabrutinib-with-
obinutuzumab
-for-chronic-lymphocytic-leukemia-cll/ CAR-T therapy has significant side effects and risks, but it knocks back the CLL in most patients.
bkoffman
CLL CURE Hero
in
CLL Support
5 years ago
Zanubrutinib, Obinutuzumab and Venetoclax. Front line Clinical Trial.
For those who may have an interest, I started on the BOVEN clinical trial at Sloan Kettering. Trial aim is to achieve MRD with a long remission. People at Sloan are top notch so far. 37 patients total in the trial. By background is diagnosed February 2016. On WW until now. 13q deleted, un-mutated. Had
For those who may have an interest, I started on the BOVEN clinical trial at Sloan Kettering. Trial aim is to achieve MRD with a long remission. People at Sloan are top notch so far. 37 patients total in the trial. By background is diagnosed February 2016. On WW until now. 13q deleted, un-mutated. Had
Awksom
in
CLL Support
5 years ago
3-year cost comparison of novel agents/combos
Easy to see the cost benefits of time-limited therapy with venetoclax-
obinutuzumab
(Gazyva). source: https://twitter.com/GomezDLeonMD/status/1187722646034751488
Easy to see the cost benefits of time-limited therapy with venetoclax-
obinutuzumab
(Gazyva). source: https://twitter.com/GomezDLeonMD/status/1187722646034751488
avzuclav
in
CLL Support
5 years ago
Adding Venetoclax to Obinutuzumab Prolongs Progression-Free Survival in Previously Untreated CLL
[i]Dated 1st September 2019[/i] In a phase III trial of patients with previously untreated CLL a
nd co-existing comorbidities, a fixed-duration regimen
of
obinutuzumab
plus venetoclax reduced the risk of disease progression and death by 65%, compared with
obinutuzumab
plus chlorambucil.
[i]Dated 1st September 2019[/i] In a phase III trial of patients with previously untreated CLL a
nd co-existing comorbidities, a fixed-duration regimen
of
obinutuzumab
plus venetoclax reduced the risk of disease progression and death by 65%, compared with
obinutuzumab
plus chlorambucil.
Jm954
Administrator
in
CLL Support
5 years ago
Use of MRD Status Following Obinutuzumab/Ibrutinib to Guide Subsequent Intensification of Therapy in CLL
More here: https://www.cancertherapyadvisor.com/home/cancer-topics/chronic-lymphocytic-leukemia/chronic-leukemia-cll-
obinutuzumab
-ibrutinib-mrd-status-guide-treatment/ Jackie
More here: https://www.cancertherapyadvisor.com/home/cancer-topics/chronic-lymphocytic-leukemia/chronic-leukemia-cll-
obinutuzumab
-ibrutinib-mrd-status-guide-treatment/ Jackie
Jm954
Administrator
in
CLL Support
5 years ago
Novel Combos Are Shaking Up the CLL Landscape but FCR still has its place
Investigators included
obinutuzumab
because previous results showed that the drug induced higher rates of MRD negativity than rituximab. Patients received 3 cycles of iFCG followed by ibrutinib for 9 cycles and
obinutuzumab
for either 3 or 9 cycles, depending upon response and MRD levels.
Investigators included
obinutuzumab
because previous results showed that the drug induced higher rates of MRD negativity than rituximab. Patients received 3 cycles of iFCG followed by ibrutinib for 9 cycles and
obinutuzumab
for either 3 or 9 cycles, depending upon response and MRD levels.
Jm954
Administrator
in
CLL Support
5 years ago
6 Videos from OncLive - Drs. Flinn, Davids, Kahl, & Pagel - Focus on Chemo Free Frontline Treatments
- Venetoclax +
Obinutuzumab
: Impact on CLL Management https://onclive.createsend1.com/t/j-l-mktuhky-jrtrfkhuh-n/ Expert clinicians reflect on combination venetoclax +
obinutuzumab
to treat chronic lymphocytic leukemia as a chemotherapy-free treatment option.
- Venetoclax +
Obinutuzumab
: Impact on CLL Management https://onclive.createsend1.com/t/j-l-mktuhky-jrtrfkhuh-n/ Expert clinicians reflect on combination venetoclax +
obinutuzumab
to treat chronic lymphocytic leukemia as a chemotherapy-free treatment option.
lankisterguy
Volunteer
in
CLL Support
5 years ago
CLL, Spleen Recovery+recommendations
I had my first dose of Gazyva or
Obinutuzumab
was a month ago and have recently taken 2 doses of Leukeran as well. I was only able to take the initial dose of Gazyva due to a reaction to the medication.
I had my first dose of Gazyva or
Obinutuzumab
was a month ago and have recently taken 2 doses of Leukeran as well. I was only able to take the initial dose of Gazyva due to a reaction to the medication.
SCE2AUX
in
CLL Support
5 years ago
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