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Rituximab and bendamustine
Hi all fellow cllers. Is anyone else on rituximab and bendamustine at the moment? I just started last Thursday- a half dose of each of them on 2 successive days. Feeling totally steamrollered for Christmas now!! I did have fludarabine and rituximab nearly 5 years ago with great results. Has anyone
Hi all fellow cllers. Is anyone else on rituximab and bendamustine at the moment? I just started last Thursday- a half dose of each of them on 2 successive days. Feeling totally steamrollered for Christmas now!! I did have fludarabine and rituximab nearly 5 years ago with great results. Has anyone
Donegal
in
CLL Support
8 years ago
Elevated LDH
Hello to all. I've been reading posts on the site for months and have found it so helpful. I was diagnosed with CLL two years ago and went through 6 cycles of BR. Now in remission, but my last blood test show an elevated LDH (328). My hemotologist has me coming back to retest in four months rather than
Hello to all. I've been reading posts on the site for months and have found it so helpful. I was diagnosed with CLL two years ago and went through 6 cycles of BR. Now in remission, but my last blood test show an elevated LDH (328). My hemotologist has me coming back to retest in four months rather than
margella
in
CLL Support
8 years ago
Weekly Paclitaxel protocol
Dear all, My mother (post surgery) is on the following adjuvant chemotherapy regimen: 1. Taxol - Paclitaxel (70mg/m2) weekly for 12 week. [This comes out to be paclitaxel 100mg weekly as her BSA is 1.48] 2. Herceptin - Trastuzumab 150mg (weekly) for 52 weeks. No prior anthracyclin or any other chemotherapy
Dear all, My mother (post surgery) is on the following adjuvant chemotherapy regimen: 1. Taxol - Paclitaxel (70mg/m2) weekly for 12 week. [This comes out to be paclitaxel 100mg weekly as her BSA is 1.48] 2. Herceptin - Trastuzumab 150mg (weekly) for 52 weeks. No prior anthracyclin or any other chemotherapy
anshul_15
in
Breast Cancer India
8 years ago
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Reprogramming the immune system - the potential for a combined approach with checkpoint inhibitors and immune signal activators
Not specific to CLL, but to NHL and HL
lymphomas
, specifically DLBCL: [i]"Dr Ansell suggested there are 3 main approaches to treating patients. One is going directly after the malignant cells and depleting them.
Not specific to CLL, but to NHL and HL
lymphomas
, specifically DLBCL: [i]"Dr Ansell suggested there are 3 main approaches to treating patients. One is going directly after the malignant cells and depleting them.
AussieNeil
Administrator
in
CLL Support
8 years ago
Bloodwise news
Blood cancer drugs kept on the Cancer Drugs Fund We're delighted to announce that NHS England have confirmed that two blood cancer treatments will continue to be available to NHS patients via the Cancer Drugs Fund. The treatments were delisted from the CDF in September, but have been readmitted following
Blood cancer drugs kept on the Cancer Drugs Fund We're delighted to announce that NHS England have confirmed that two blood cancer treatments will continue to be available to NHS patients via the Cancer Drugs Fund. The treatments were delisted from the CDF in September, but have been readmitted following
Hidden
in
CLL Support
8 years ago
Newbie
Hello, I am new to RA diagnosed in April, this year, I have had loads of problems, with suspected
Lymphomas
negative thank goodness, and problems with DMARDS going back onto Sulfasalazine liquid this week, had to come off because of being ill with horrible cold! I seem to have constant Flare Ups!
Hello, I am new to RA diagnosed in April, this year, I have had loads of problems, with suspected
Lymphomas
negative thank goodness, and problems with DMARDS going back onto Sulfasalazine liquid this week, had to come off because of being ill with horrible cold! I seem to have constant Flare Ups!
Pmr650
in
NRAS
8 years ago
Brain Aneurysms, Brain Tumours & Stage 3 Non Hodgkins Lymphoma in less than 3 months....my carer, Husband and Father!
Zero support, mentally, or physically. His daughter, now 25 was diagnosed with 6cm Brain Aneurysm this time last year, and still recovering from coiling that has slowed the aneurysm a little. Yet, my hubby 47, is blanked, repeatedly told not to worry...it's doubtful my hubby, his daughter and his
Zero support, mentally, or physically. His daughter, now 25 was diagnosed with 6cm Brain Aneurysm this time last year, and still recovering from coiling that has slowed the aneurysm a little. Yet, my hubby 47, is blanked, repeatedly told not to worry...it's doubtful my hubby, his daughter and his
Claire71uk
in
Pain Concern
8 years ago
Possible genetic key in Diffuse Large B-cell lymphoma (DLBCL) may explain why some patients don't respond to treatment
Oxford researchers funded by the UK blood cancer charity Bloodwise, [i]"have found that high levels of shortened forms of a protein, known as FOXP1, in a patient's lymphoma cells enable the cancer to evade the immune system, potentially nearly halving survival rates for these patients"[/i]: http://www.medicalnewstoday.com
Oxford researchers funded by the UK blood cancer charity Bloodwise, [i]"have found that high levels of shortened forms of a protein, known as FOXP1, in a patient's lymphoma cells enable the cancer to evade the immune system, potentially nearly halving survival rates for these patients"[/i]: http://www.medicalnewstoday.com
AussieNeil
Administrator
in
CLL Support
8 years ago
Plant-derived compound shows activity against Non Hodgkin Lymphoma (NHL). CLL is a NHL.
[i]"The active compound in a plant extract has shown promise for treating non-Hodgkin
lymphomas
(NHLs), according to researchers.
[i]"The active compound in a plant extract has shown promise for treating non-Hodgkin
lymphomas
(NHLs), according to researchers.
AussieNeil
Administrator
in
CLL Support
8 years ago
Variability in platelet count
I am ten weeks into the clinical trial with ACP-196 and all is going well. My white count rose and peaked at about day 60 and has decreased 25% to today (day 85). I arbitrarily put a cubic polynomial through these data. https://www.desmos.com/calculator/x6fbswb2lq But the platelets are all over the
I am ten weeks into the clinical trial with ACP-196 and all is going well. My white count rose and peaked at about day 60 and has decreased 25% to today (day 85). I arbitrarily put a cubic polynomial through these data. https://www.desmos.com/calculator/x6fbswb2lq But the platelets are all over the
Ramses
in
CLL Support
8 years ago
CLL relapse and Bendamustine
Hi, My dad has CLL and is possibly going to need more chemo in the next couple of months. The consultant said it would be Bendamustine but I've read that this drug is possibly going to be delisted in November. Please can anyone advise on an alternative if it is delisted or is it possible to get the
Hi, My dad has CLL and is possibly going to need more chemo in the next couple of months. The consultant said it would be Bendamustine but I've read that this drug is possibly going to be delisted in November. Please can anyone advise on an alternative if it is delisted or is it possible to get the
Sara2013
in
CLL Support
8 years ago
Another new one
Just found your group and thought I'd say hello. No major issues at the moment but it's always good to stay connected. I was diagnosed in 2009, required treatment earlier this year, and am now in a partial remission. I had bendamustine, Rituxan, and Idelalisib as part of a clinical trial but failed
Just found your group and thought I'd say hello. No major issues at the moment but it's always good to stay connected. I was diagnosed in 2009, required treatment earlier this year, and am now in a partial remission. I had bendamustine, Rituxan, and Idelalisib as part of a clinical trial but failed
Eagle5327
in
CLL Support
8 years ago
Portable White Blood Cell Counter in Development
Particularly, in the case of patients with
lymphomas
and leukaemia, "treatment doses could be maximised for each individual without compromising their immunological system. Treatment efficiency could be improved while reducing the risk of suffering serious infections.
Particularly, in the case of patients with
lymphomas
and leukaemia, "treatment doses could be maximised for each individual without compromising their immunological system. Treatment efficiency could be improved while reducing the risk of suffering serious infections.
AussieNeil
Administrator
in
CLL Support
8 years ago
FDA updates warning about Bendamustine (Trenda)
The FDA issued a statement, warning healthcare professionals not to use the chemotherapy drug Treanda Injection (bendamustine hydrochloride) with closed system transfer devices (CSTDs), adapters, and syringes containing polycarbonate or acrylonitrile-butadiene-styrene (ABS). In an expanding world of
The FDA issued a statement, warning healthcare professionals not to use the chemotherapy drug Treanda Injection (bendamustine hydrochloride) with closed system transfer devices (CSTDs), adapters, and syringes containing polycarbonate or acrylonitrile-butadiene-styrene (ABS). In an expanding world of
ThreeWs
in
CLL Support
9 years ago
MRD negative
After 6 rounds of FCR (2 rounds of 5 x days F&C, and 4 rounds with just 3 days of taking the tablets) we got the results of my husband's bone marrow biopsy yesterday. It was the best possible news - he is MRD negative ( minimal residual disease) ie complete remission. It was tough, but obviously worth
After 6 rounds of FCR (2 rounds of 5 x days F&C, and 4 rounds with just 3 days of taking the tablets) we got the results of my husband's bone marrow biopsy yesterday. It was the best possible news - he is MRD negative ( minimal residual disease) ie complete remission. It was tough, but obviously worth
Fowey2009
in
CLL Support
9 years ago
Joe Parzych,
Am a relapsed CLL patient, residing in West suburban Chicago. First diagnosed in 2008, and receive care at Nithwestern Hospital in Chicago. Started participation of clinical trial March 2014, ABT-199 and Rituxan. In remission since December 2014. Feeling very good.
Am a relapsed CLL patient, residing in West suburban Chicago. First diagnosed in 2008, and receive care at Nithwestern Hospital in Chicago. Started participation of clinical trial March 2014, ABT-199 and Rituxan. In remission since December 2014. Feeling very good.
Parzych
in
CLL Support
9 years ago
Checkpoint Inhibitors - the Programmed Death 1 and Ligand (PD-1/PD-L1) checkpoints and their promise for CLL/SLL
[/i] [i]"The anti-CD20 antibody rituximab, the first monoclonal antibody approved for treating cancer, revolutionized the therapy of B-cell
lymphomas
in 1997.
[/i] [i]"The anti-CD20 antibody rituximab, the first monoclonal antibody approved for treating cancer, revolutionized the therapy of B-cell
lymphomas
in 1997.
AussieNeil
Administrator
in
CLL Support
9 years ago
Guide to buying supplements in UK
Interesting programme on TV last week, BBC's 'Trust Me I'm a Doctor', that is relevant for anyone buying supplements in the UK. http://www.bbc.co.uk/programmes/articles/4hX30rMYkMv9YjMTH38MY6/do-herbal-supplements-contain-what-they-say-on-the-label I always thought that the UK supplement industry had
Interesting programme on TV last week, BBC's 'Trust Me I'm a Doctor', that is relevant for anyone buying supplements in the UK. http://www.bbc.co.uk/programmes/articles/4hX30rMYkMv9YjMTH38MY6/do-herbal-supplements-contain-what-they-say-on-the-label I always thought that the UK supplement industry had
badpiglet
in
PBC Foundation
9 years ago
Hopeful
Hey everyone, Today has been one of them achy hurting day's, so hubby went into town and brought me a massive tub of Epsom salts and magnesium citrate - never tried these before. So even though today sucks I'm feeling hopeful these will work/help? Plus side I'm enjoying a lazy day and had a not so pleasant
Hey everyone, Today has been one of them achy hurting day's, so hubby went into town and brought me a massive tub of Epsom salts and magnesium citrate - never tried these before. So even though today sucks I'm feeling hopeful these will work/help? Plus side I'm enjoying a lazy day and had a not so pleasant
Keeleybee
in
Fibromyalgia Action UK
9 years ago
Hodgkin's Disease
Pet-Ct Impression after 3 Chemotherapy Cycles: 1.Scan doesnot reveal any abnormal hypermetabolic lesion anywhere in the entire torso. 2.Mild Splenomegaly. 3. Only non FDG- avid small nodes noted in the cervical,axillary, mediastinal & abdominal region. 4. No other evidence of metabolically active disease
Pet-Ct Impression after 3 Chemotherapy Cycles: 1.Scan doesnot reveal any abnormal hypermetabolic lesion anywhere in the entire torso. 2.Mild Splenomegaly. 3. Only non FDG- avid small nodes noted in the cervical,axillary, mediastinal & abdominal region. 4. No other evidence of metabolically active disease
babu57
in
Breast Cancer India
9 years ago
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