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Leuprolide
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Muscle pain from ADT
https://www.rtihs.org/publications/comparison-impact-degarelix-and-
leuprolide
-health-related-quality-life-patients However, I am very hesitant in switching to
leuprolide
since Firmagon appears to have other significant long-term benefits which is why I chose this therapy.
https://www.rtihs.org/publications/comparison-impact-degarelix-and-
leuprolide
-health-related-quality-life-patients However, I am very hesitant in switching to
leuprolide
since Firmagon appears to have other significant long-term benefits which is why I chose this therapy.
Purple-Bike
in
Advanced Prostate Cancer
3 years ago
Leg edema
Leuprolide
and abiraterone + prednisone for 2 years with most all the usual ADT SEs and PSA < 0.1 so far. A couple of months ago, I noticed significant but not severe swelling of my R calf and minor swelling of L calf.
Leuprolide
and abiraterone + prednisone for 2 years with most all the usual ADT SEs and PSA < 0.1 so far. A couple of months ago, I noticed significant but not severe swelling of my R calf and minor swelling of L calf.
Gearhead
in
Advanced Prostate Cancer
3 years ago
What next? Abiraterone->Docetaxel->Cabazitaxel-> ?
earlier used with prednisolone and also not aware about steroid switch)
[u]Dad treatment history: [/u]
Dx at Jan 2018 at age of 49yr, Baseline PSA 2500,GS-10,St-4, adenocarcinoma ca prostate with extensive LN mets and bone mets (bone marrow involved), started with Abiretrone/prednisolone +
leuprolide
earlier used with prednisolone and also not aware about steroid switch)
[u]Dad treatment history: [/u]
Dx at Jan 2018 at age of 49yr, Baseline PSA 2500,GS-10,St-4, adenocarcinoma ca prostate with extensive LN mets and bone mets (bone marrow involved), started with Abiretrone/prednisolone +
leuprolide
pka21
in
Advanced Prostate Cancer
3 years ago
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First Follow Up on MyTestosterone Trial
Intolerant/allergic to
leuprolide
so I did alternative ADT after BCR with bicalutamide 50mg plus dutasteride for 5 years before it failed. In 2019 I had Ga-68-PSMA scan showing only two PLNs in pelvis on left side. No activity elsewhere. So I did hemipelvis IMRT, 64 Gy with boost to the 2 nodes.
Intolerant/allergic to
leuprolide
so I did alternative ADT after BCR with bicalutamide 50mg plus dutasteride for 5 years before it failed. In 2019 I had Ga-68-PSMA scan showing only two PLNs in pelvis on left side. No activity elsewhere. So I did hemipelvis IMRT, 64 Gy with boost to the 2 nodes.
MateoBeach
in
Advanced Prostate Cancer
3 years ago
My case is moving along about to start treatments any suggestions
Was going to start
Leuprolide
(Eligard) shot today but insurance was still pending ,they should be calling me real soon to reschedule. I’m sure TAll Allen has it pegged ADT with whole salvage pelvic radiation is coming. BTW T level is 245 as I haven’t had any treatments yet!
Was going to start
Leuprolide
(Eligard) shot today but insurance was still pending ,they should be calling me real soon to reschedule. I’m sure TAll Allen has it pegged ADT with whole salvage pelvic radiation is coming. BTW T level is 245 as I haven’t had any treatments yet!
CLcarter
in
Advanced Prostate Cancer
3 years ago
tE2 – History, Sourcing, and obstacles in the US
I’m writing this post with a preamble that these are my opinions, and I cannot prove any of them, nor am I trying to prove them. So, please read these conclusions with this information in mind. I believe that information about tE2 is difficult to uncover because in the US, the medical industrial complex
I’m writing this post with a preamble that these are my opinions, and I cannot prove any of them, nor am I trying to prove them. So, please read these conclusions with this information in mind. I believe that information about tE2 is difficult to uncover because in the US, the medical industrial complex
ragnar2020
in
Advanced Prostate Cancer
3 years ago
Desperately Seeking Susan...um...2nd Opinion
So I’m on 1st gen
leuprolide
/lupron + 2nd gen apalutamide/erleada(and others). Heavy, some unusual side effects = no surprise to me. Excellent, fast metric plunges. I want a 2nd opinion from a super-expert.
So I’m on 1st gen
leuprolide
/lupron + 2nd gen apalutamide/erleada(and others). Heavy, some unusual side effects = no surprise to me. Excellent, fast metric plunges. I want a 2nd opinion from a super-expert.
pete-ginger
in
Advanced Prostate Cancer
3 years ago
Facial Flushing and heat continued after Prostap/ Leuprorelin
I went on course of prostap for 3 or 4 months for a surgery. I have been off Prostap now for 2 years and I still experience facial flushing and heat whenever I get hot, anxious or nervous or sometimes when I drink alcohol. Sometimes for no reason at all! Its really starting to get to me, as going bright
I went on course of prostap for 3 or 4 months for a surgery. I have been off Prostap now for 2 years and I still experience facial flushing and heat whenever I get hot, anxious or nervous or sometimes when I drink alcohol. Sometimes for no reason at all! Its really starting to get to me, as going bright
123456789101117
in
Endometriosis UK
3 years ago
FDA has approved Relugolix (Orgovyx) for advanced PCa.
The most common AE across all grades in both arms was hot flash, occurring in 54.3% and 51.6% of the relugolix and
leuprolide
cohorts, respectively. There was a higher incidence of all-grade diarrhea with relugolix at 12.2% versus 6.8% with
leuprolide
.
The most common AE across all grades in both arms was hot flash, occurring in 54.3% and 51.6% of the relugolix and
leuprolide
cohorts, respectively. There was a higher incidence of all-grade diarrhea with relugolix at 12.2% versus 6.8% with
leuprolide
.
pjoshea13
in
Advanced Prostate Cancer
3 years ago
EMBARK trial results already available?
EMBARK is a randomized Phase 3 study of enzalutamide plus
leuprolide
, enzalutamide monotherapy, and
leuprolide
alone in men with high-risk non-metastatic HSPC.
EMBARK is a randomized Phase 3 study of enzalutamide plus
leuprolide
, enzalutamide monotherapy, and
leuprolide
alone in men with high-risk non-metastatic HSPC.
GP24
in
Advanced Prostate Cancer
3 years ago
Update to Can't treat what we can't see
He does continue on
leuprolide
. Patient should continue on
leuprolide
throughout duration of chemotherapy. Dr. Kwon like to see the patient back 1 to 2 weeks after his 3rd cycle for repeat evaluation. If PSA is not down trending or there is further advancement of metastatic disease on imaging, Dr.
He does continue on
leuprolide
. Patient should continue on
leuprolide
throughout duration of chemotherapy. Dr. Kwon like to see the patient back 1 to 2 weeks after his 3rd cycle for repeat evaluation. If PSA is not down trending or there is further advancement of metastatic disease on imaging, Dr.
SF22
in
Advanced Prostate Cancer
3 years ago
Oral Relumina better that leuprolide in HERO trial
"The data demonstrated that the risk for a major cardiovascular event was reduced by 54% in patients who received Relumina compared to
leuprolide
." https://www.curetoday.com/view/relumina-appears-superior-to-hormone-associated-therapy-
leuprolide
-for-patients-with-advanced-prostate-cancer
"The data demonstrated that the risk for a major cardiovascular event was reduced by 54% in patients who received Relumina compared to
leuprolide
." https://www.curetoday.com/view/relumina-appears-superior-to-hormone-associated-therapy-
leuprolide
-for-patients-with-advanced-prostate-cancer
George71
in
Advanced Prostate Cancer
4 years ago
6-month Update: PSA down / Testosterone up
B) Change
Leuprolide
for any other LHRH agonist like Triptorelin or Goserelin (this wouldnt be economically viable, since it has to be paid from our empty pocket because public system only have
Leuprolide
).
B) Change
Leuprolide
for any other LHRH agonist like Triptorelin or Goserelin (this wouldnt be economically viable, since it has to be paid from our empty pocket because public system only have
Leuprolide
).
olloreda
in
Advanced Prostate Cancer
4 years ago
Resetting the Bar of Castration Resistance - Understanding Androgen Dynamics in Therapy Resistance and Treatment Choice in PCa
LUPRON DEPOT® (
leuprolide
acetate for depot suspension) [prescribing information]: AbbVie Inc.; 1989. 23. ELIGARD® (
leuprolide
acetate for injectable suspension) [prescribing information]: Tolmar Pharmaceuticals, Inc.; 2002. 24. Crawford ED, Twardowski PW, Concepcion RS, et al.
LUPRON DEPOT® (
leuprolide
acetate for depot suspension) [prescribing information]: AbbVie Inc.; 1989. 23. ELIGARD® (
leuprolide
acetate for injectable suspension) [prescribing information]: Tolmar Pharmaceuticals, Inc.; 2002. 24. Crawford ED, Twardowski PW, Concepcion RS, et al.
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Vagifem - Estradiol
Hello ladies, It’s been now a second month I’m being prescribed Vagifem. The hot flashes are getting stronger. The cold sweats are unbearable.... Also realised that each flare is lasting longer (spent 2 weeks unable to make a move).. I don’t know if it’s the fact that I was 2y under Decapeptyl (
Hello ladies, It’s been now a second month I’m being prescribed Vagifem. The hot flashes are getting stronger. The cold sweats are unbearable.... Also realised that each flare is lasting longer (spent 2 weeks unable to make a move).. I don’t know if it’s the fact that I was 2y under Decapeptyl (
Sorayaq
in
Endometriosis UK
3 years ago
Chemo not working for bone mets
Greetings, I joined the group back in August and your posts have been so very helpful. So I’m new here. My husband has advanced PC. History: Scott was experiencing back pain last winter that he thought was job-related. He is an underwater construction diver in the NY metro area. The chiropractor told
Greetings, I joined the group back in August and your posts have been so very helpful. So I’m new here. My husband has advanced PC. History: Scott was experiencing back pain last winter that he thought was job-related. He is an underwater construction diver in the NY metro area. The chiropractor told
Lavender22
in
Advanced Prostate Cancer
3 years ago
Update regarding divergent advice about adding Zytiga to Lupron when PSA undetectable
Leuprolide
was started and he had RT to prostate bed and S4 in 5/2018. PSA became undetectable in 2/2019. Tumor profiling showed somatic but not germline BRCA2 mutation. At this point he has had 2+ years of ADT. There are 2 questions.
Leuprolide
was started and he had RT to prostate bed and S4 in 5/2018. PSA became undetectable in 2/2019. Tumor profiling showed somatic but not germline BRCA2 mutation. At this point he has had 2+ years of ADT. There are 2 questions.
Istomin
in
Advanced Prostate Cancer
4 years ago
Sorry if
Hi all , I am 33 was diagnosed with Endometriosis and Dyspareunia 4 years ago by laparoscopy diathermy and insertion of Marina, to which i was I had some relief for roughly 6 months then late 2017 I was given Leuprorelin (Prostap, Lutrate) injections for 3 months these helped my cramps but the headache
Hi all , I am 33 was diagnosed with Endometriosis and Dyspareunia 4 years ago by laparoscopy diathermy and insertion of Marina, to which i was I had some relief for roughly 6 months then late 2017 I was given Leuprorelin (Prostap, Lutrate) injections for 3 months these helped my cramps but the headache
kitten4687
in
The Endometriosis Foundation
4 years ago
Preparing for Provenge
Current treatment
Leuprolide
, radiation. Shortly after diagnosis three spots on legs and shoulder were zapped, and scheduled next week for radiation on new spots in my spine and wag. PSA was under .1 until three months ago has now inched up to .79.
Current treatment
Leuprolide
, radiation. Shortly after diagnosis three spots on legs and shoulder were zapped, and scheduled next week for radiation on new spots in my spine and wag. PSA was under .1 until three months ago has now inched up to .79.
Bigpike
in
Advanced Prostate Cancer
4 years ago
Lupron shortage update from the FDA
AI=
Leuprolide
%20Acetate%20Injection&st=c&tab=tabs-1
AI=
Leuprolide
%20Acetate%20Injection&st=c&tab=tabs-1
V10fanatic
in
Advanced Prostate Cancer
4 years ago
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