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Updated x2: NAC May Mitigate Coronavirus Severity, also Potential Risks
From an article entitled: "Nutraceuticals have potential for boosting the type 1
interferon
response to RNA viruses including influenza and coronavirus": https://www.sciencedirect.com/science/article/pii/S0033062020300372?
From an article entitled: "Nutraceuticals have potential for boosting the type 1
interferon
response to RNA viruses including influenza and coronavirus": https://www.sciencedirect.com/science/article/pii/S0033062020300372?
park_bear
in
Cure Parkinson's
4 years ago
Is anyone else like WTF?
Ive read the posts about
interferon
side effects and hopeful for the best. How have others coped mentally? How do you deal with the knowledge that your ET may become something worse but also may not?!? How do you talk about it with your friends? Your kids? Your spouse?
Ive read the posts about
interferon
side effects and hopeful for the best. How have others coped mentally? How do you deal with the knowledge that your ET may become something worse but also may not?!? How do you talk about it with your friends? Your kids? Your spouse?
JT_Marlin
in
MPN Voice
4 years ago
🇮🇹 Italy Using Prone Positioning With Regard Coronavirus
In today’s papers was article about Italy having coronavirus patients face down in bed’s Not really sure how that works SO did bit of reading ANYWAY seems like last ditch effort to open alveolar from total collapse. Think it’s called atlectasas BUT this complication is caused by sars-cov virus that
In today’s papers was article about Italy having coronavirus patients face down in bed’s Not really sure how that works SO did bit of reading ANYWAY seems like last ditch effort to open alveolar from total collapse. Think it’s called atlectasas BUT this complication is caused by sars-cov virus that
Hidden
in
Lung Conditions Community Forum
4 years ago
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Recommendation on Haematologist in London
I want 2nd opinion on starting
Interferon
for short period to get a break from Hydrea to plan family.
I want 2nd opinion on starting
Interferon
for short period to get a break from Hydrea to plan family.
MrThara
in
MPN Voice
4 years ago
Going on interferon pegasys
Hi everyone, and happy new year 💞 From next Wednesday I am having to go onto
interferon
pegasys injections....wish me luck. 😘😘
Hi everyone, and happy new year 💞 From next Wednesday I am having to go onto
interferon
pegasys injections....wish me luck. 😘😘
Yvette49
in
MPN Voice
4 years ago
Positive Results on Anifrolumab for Lupus Published in New England Journal of Medicine
For full background on Type I
Interferon
in lupus.
For full background on Type I
Interferon
in lupus.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
4 years ago
Latest results from MDA immunotherapy. trial for mCRPC using ipilimumab. MedPageToday & Science Translational Medicine - April 2020
"We published a study several years ago showing that when you give anti-CTLA-4,
interferon
-gamma is produced by the T cells and then PD-1 and PD-L1 are upregulated," said senior author Padmanee Sharma, MD, PhD, also of MD Anderson.
"We published a study several years ago showing that when you give anti-CTLA-4,
interferon
-gamma is produced by the T cells and then PD-1 and PD-L1 are upregulated," said senior author Padmanee Sharma, MD, PhD, also of MD Anderson.
cujoe
in
Fight Prostate Cancer
4 years ago
Taking Peginterferon
Today I will be taking my first Peg
Interferon
injection - starting on 45mcg once a week. What’s everyone’s routine for taking it?.
Today I will be taking my first Peg
Interferon
injection - starting on 45mcg once a week. What’s everyone’s routine for taking it?.
Tylerdog1
in
MPN Voice
4 years ago
Hydroxycarbamide to interferon injection and side effects
I've been on 90ml
interferon
weekly for 6 weeks now and had suffered a sinus infection and flu symptoms since starting on the injections. I feel I have flu constantly achy and skin hot. I've had 2 lots of antibiotics. I'm due back to clinic in 2 weeks.
I've been on 90ml
interferon
weekly for 6 weeks now and had suffered a sinus infection and flu symptoms since starting on the injections. I feel I have flu constantly achy and skin hot. I've had 2 lots of antibiotics. I'm due back to clinic in 2 weeks.
Sam247
in
MPN Voice
4 years ago
LRA Celebrates Major Research Breakthroughs in 2019
First Promising, Phase 2 Trial Demonstrates Effectiveness of a Second
Interferon
Inhibitor — Positive Phase 2 trial results for Biogen’s type I
interferon
inhibitor BIIB059 demonstrated that it met clinical endpoints in patients with cutaneous lupus (skin related lupus) as well as in systemic lupus.
First Promising, Phase 2 Trial Demonstrates Effectiveness of a Second
Interferon
Inhibitor — Positive Phase 2 trial results for Biogen’s type I
interferon
inhibitor BIIB059 demonstrated that it met clinical endpoints in patients with cutaneous lupus (skin related lupus) as well as in systemic lupus.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
4 years ago
LRA Celebrates Major Research Breakthroughs in 2019
First Promising, Phase 2 Trial Demonstrates Effectiveness of a Second
Inhibitor — Positive Phase 2 trial results for Biogen’s type I
interferon
inhibitor BIIB059 demonstrated that it met clinical endpoints in patients with cutaneous lupus (skin related lupus) as well as in systemic
First Promising, Phase 2 Trial Demonstrates Effectiveness of a Second
Inhibitor — Positive Phase 2 trial results for Biogen’s type I
interferon
inhibitor BIIB059 demonstrated that it met clinical endpoints in patients with cutaneous lupus (skin related lupus) as well as in systemic
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
4 years ago
Lupus Flares May Be Linked to Damage to Mitochondria, Study Reports
JANUARY 17, 2020 BY JOANA CARVALHO Lupus Flares May Be Linked to Damage to Mitochondria, Study Reports Excessive production of type I
interferon
(IFN-I) — a molecule that mediates immune and inflammatory responses — in people with systemic lupus erythematosus (SLE) may be caused by small fragments of
JANUARY 17, 2020 BY JOANA CARVALHO Lupus Flares May Be Linked to Damage to Mitochondria, Study Reports Excessive production of type I
interferon
(IFN-I) — a molecule that mediates immune and inflammatory responses — in people with systemic lupus erythematosus (SLE) may be caused by small fragments of
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
4 years ago
Newly joined
It is now changing to Myeloid Fibrosis, still with no symptoms - but nows the time to start taking
Interferon
to manage it . Wondering what people’s experience of taking this is
It is now changing to Myeloid Fibrosis, still with no symptoms - but nows the time to start taking
Interferon
to manage it . Wondering what people’s experience of taking this is
Tylerdog1
in
MPN Voice
4 years ago
Breakthrough science provides hope for lupus patients
Between 60% and 80% of adults with SLE show increased
interferon
-induced genes, which reflect overproduction of the immune protein Type 1
interferon
.
Between 60% and 80% of adults with SLE show increased
interferon
-induced genes, which reflect overproduction of the immune protein Type 1
interferon
.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
4 years ago
Advice for Patients with Myeloproliferative Neoplasms - 19th March 2020
such as heart disease, high blood pressure or diabetes, are considered more vulnerable and should follow the government’s guidelines for vulnerable individuals (see link above). 3.Patients under 70 years of age who are on medications to control their blood count or their MPN like Hydroxycarbamide,
Interferon
such as heart disease, high blood pressure or diabetes, are considered more vulnerable and should follow the government’s guidelines for vulnerable individuals (see link above). 3.Patients under 70 years of age who are on medications to control their blood count or their MPN like Hydroxycarbamide,
Interferon
Mazcd
MPNVoice
in
MPN Voice
4 years ago
Some hope for us re: Coronavirus?
Sixteen of the remaining regimens contain an
interferon
-based product. The rest include a variety of antimicrobials, corticosteroids, convalescent plasma, and biologics.
Sixteen of the remaining regimens contain an
interferon
-based product. The rest include a variety of antimicrobials, corticosteroids, convalescent plasma, and biologics.
milkwoman
in
LUPUS UK
4 years ago
Availability of Interferon Scotland
I am currently on Pegylated
Interferon
and we are considering moving to Scotland, and wondered if this drug is readily available in hospitals there. I know that not all hospitals here in England provide it and hence the question regarding Scotland.
I am currently on Pegylated
Interferon
and we are considering moving to Scotland, and wondered if this drug is readily available in hospitals there. I know that not all hospitals here in England provide it and hence the question regarding Scotland.
AnitaJ
in
MPN Voice
4 years ago
Change from Interferon to Pegasys
At last my trust has approved the change from basic
Interferon
to Pegasys. I have only been allowed standard
Interferon
for the past year, but the last few months my platlets have risen from 350 to nearly 700, and I have had to increase my injections to every other day.
At last my trust has approved the change from basic
Interferon
to Pegasys. I have only been allowed standard
Interferon
for the past year, but the last few months my platlets have risen from 350 to nearly 700, and I have had to increase my injections to every other day.
swimswam
in
MPN Voice
4 years ago
New treatment options
https://www.targetedonc.com/news/expert-highlights-benefits-of-fedratinib-in-subgroup-of-patients-with-myelofibrosis Mesa: It’s an exciting time in MPNs without a doubt. I would break it down into 2 advances. The first is in patients with ET and PV. At this meeting, there continues to be further updates
https://www.targetedonc.com/news/expert-highlights-benefits-of-fedratinib-in-subgroup-of-patients-with-myelofibrosis Mesa: It’s an exciting time in MPNs without a doubt. I would break it down into 2 advances. The first is in patients with ET and PV. At this meeting, there continues to be further updates
Paul123456
in
MPN Voice
4 years ago
Pegasys and breast feeding
I injected
interferon
throughout pregnancy and thankfully all went well. I now need to start taking it again. I'm currently breast feeding and would like to continue. I appreciate there probably isn't very much evidence about this but does anyone have any insight? Or has anyone done it?
I injected
interferon
throughout pregnancy and thankfully all went well. I now need to start taking it again. I'm currently breast feeding and would like to continue. I appreciate there probably isn't very much evidence about this but does anyone have any insight? Or has anyone done it?
hansyhand
in
MPN Voice
4 years ago
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