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Now I am scared.....
Hello - I was reading a post on Facebook and there was a reference to a wicked condition called Calciphyaxis. It affects some ESRD patients and is quite prevalent in type 2 patients who inject with insulin - caused by the needle going in. Thats me. I wish I had never seen that post because it has scared
Hello - I was reading a post on Facebook and there was a reference to a wicked condition called Calciphyaxis. It affects some ESRD patients and is quite prevalent in type 2 patients who inject with insulin - caused by the needle going in. Thats me. I wish I had never seen that post because it has scared
fartikins
in
Kidney Disease
2 years ago
Carvedilol and low blood sugars
Have any type 1 diabetics who take carvedilol found their blood sugars drop in that beta blocker. I have switched from bisoprolol to carvedilol and my blood sugars have really dropped. I have just adjusted my insulin accordingly but I wondered if it is a side effect of that medication.
Have any type 1 diabetics who take carvedilol found their blood sugars drop in that beta blocker. I have switched from bisoprolol to carvedilol and my blood sugars have really dropped. I have just adjusted my insulin accordingly but I wondered if it is a side effect of that medication.
Caitlyn6
in
British Heart Foundation
2 years ago
Having a bit of a trying time.
Hello - the last few days have been not so good - no energy or motivation and this morning I had my breakfast and felt so sick afterwards I had to go back to bed. It has been slowly going downhill for a few days now.My biggest worry is that this all points to kidney function and the dialysis question
Hello - the last few days have been not so good - no energy or motivation and this morning I had my breakfast and felt so sick afterwards I had to go back to bed. It has been slowly going downhill for a few days now.My biggest worry is that this all points to kidney function and the dialysis question
fartikins
in
Kidney Disease
2 years ago
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Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway 2020 (Honokiol)
More positive info on Honokiol: Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956494/ So this paper is all about activating Sirt 3 to decrease alpha synuclean: "Together, our findings suggest that pharmacologically
More positive info on Honokiol: Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956494/ So this paper is all about activating Sirt 3 to decrease alpha synuclean: "Together, our findings suggest that pharmacologically
Bolt_Upright
in
Cure Parkinson's
2 years ago
Efficacy of Once- Weekly semaglutide V/s Thrice Daily Insulin Aspart as Add-on to Metformin and Insulin Glargine in Type 2 Diabetes..
Type 2 diabetes is a progressive disease, requiring treatment intensification. May have a look at the recent article published in [i]
Diabetes
[/i] journal. TAKE-HOME MESSAGE… * In the SUSTAIN 11 trial, the investigators compared weekly semaglutide to meal-time insulin aspart in patients with type
Type 2 diabetes is a progressive disease, requiring treatment intensification. May have a look at the recent article published in [i]
Diabetes
[/i] journal. TAKE-HOME MESSAGE… * In the SUSTAIN 11 trial, the investigators compared weekly semaglutide to meal-time insulin aspart in patients with type
DRH-sangli
Star
in
Diabetes India
2 years ago
Urgent advice needed on labs - very very high FT3, I'm freaking out.
Hello, Below are the results of my labs I had done this Friday. I have been taking T3 only for a year. I kept increasing the dose because I don't have any symptoms of hyperthyroid or too much T3. My pulse is around 60, blood pressure is very low, BBT around 36, and that is only recently since I had
Hello, Below are the results of my labs I had done this Friday. I have been taking T3 only for a year. I kept increasing the dose because I don't have any symptoms of hyperthyroid or too much T3. My pulse is around 60, blood pressure is very low, BBT around 36, and that is only recently since I had
Charlyemmalouise
in
Thyroid UK
2 years ago
Allergies, Sensors Oh My!
Well, I've had a few days recently dealing with allergies due to the weather and season changes. When this happens, my numbers start going like an interesting roller coaster ride. Sometimes, it also makes my family think I have a cold, when I don't feel sick/have cold symptoms. Today, I still have
Well, I've had a few days recently dealing with allergies due to the weather and season changes. When this happens, my numbers start going like an interesting roller coaster ride. Sometimes, it also makes my family think I have a cold, when I don't feel sick/have cold symptoms. Today, I still have
Activity2004
Administrator
in
Diabetes Research & Wellness Foundation
2 years ago
The Role Of Bile Acids In Prostate Cancer
Bile acids (BAs) belong to cholesterol-derived sterols. Due to the side chain carboxyl group and hydroxylation of their steroid ring they are more polar than cholesterol. They have an amphipatic character for which they are known as natural detergents. Majority of cholesterol is excreted by bile acids
Bile acids (BAs) belong to cholesterol-derived sterols. Due to the side chain carboxyl group and hydroxylation of their steroid ring they are more polar than cholesterol. They have an amphipatic character for which they are known as natural detergents. Majority of cholesterol is excreted by bile acids
Hidden
in
Advanced Prostate Cancer
2 years ago
Inhibition of Stearoyl-CoA Desaturase by Sterculic Oil Reduces Proliferation and Induces Apoptosis in Prostate Cancer Cells
Prostate cancer (PCa) is a common type of cancer affecting male population. PCa treatments have side effects and are temporarily effective, so new therapeutic options are being investigated. Due to the high demand of energy for cell proliferation, an increase in the expression and activity of lipogenic
Prostate cancer (PCa) is a common type of cancer affecting male population. PCa treatments have side effects and are temporarily effective, so new therapeutic options are being investigated. Due to the high demand of energy for cell proliferation, an increase in the expression and activity of lipogenic
Hidden
in
Advanced Prostate Cancer
2 years ago
Re-Expression of ... AR in Receptor Negative Endocrine Cancers via GSK3 Inhibition. Lithium?
New study below [1] Might interest those who have treatment-emergent loss of androgen receptor [AR]. "GSK-3 has been the subject of much research since it has been implicated in a number of diseases, including type 2 diabetes, Alzheimer's disease, inflammation, cancer, and bipolar disorder." [2] "It
New study below [1] Might interest those who have treatment-emergent loss of androgen receptor [AR]. "GSK-3 has been the subject of much research since it has been implicated in a number of diseases, including type 2 diabetes, Alzheimer's disease, inflammation, cancer, and bipolar disorder." [2] "It
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Macular Oedema
This week I went for my years late retinal screening. I had noticed I was starting to struggle with small print but put it down to using an old pair of reading glasses (my 2019 ones having broken) and maybe needing some laser treatment. The outcome was a shock. There is no need for anything like laser
This week I went for my years late retinal screening. I had noticed I was starting to struggle with small print but put it down to using an old pair of reading glasses (my 2019 ones having broken) and maybe needing some laser treatment. The outcome was a shock. There is no need for anything like laser
MichaelJH
in
Macular Society
2 years ago
INBRAIN PHARMA: direct injection of dopamine into the brain
Injecting dopamine directly into the brain using a small internal pump is what Lille researchers have succeeded in limiting the adverse effects of conventional drugs linked to Parkinson's disease. The InBrain Pharma team is pleased to see its therapeutic solution - backed by very promising initial safety
Injecting dopamine directly into the brain using a small internal pump is what Lille researchers have succeeded in limiting the adverse effects of conventional drugs linked to Parkinson's disease. The InBrain Pharma team is pleased to see its therapeutic solution - backed by very promising initial safety
Hidden
in
Cure Parkinson's
2 years ago
Hello!
Hi everyone, I’m a T1D and was diagnosed at age 26yrs. I was originally misdiagnosed as T2D by my GP and started on metformin. Although it worked for a while, I became progressively sicker and was later referred into the hospital for support. Like many people, I manage my diabetes with a combination
Hi everyone, I’m a T1D and was diagnosed at age 26yrs. I was originally misdiagnosed as T2D by my GP and started on metformin. Although it worked for a while, I became progressively sicker and was later referred into the hospital for support. Like many people, I manage my diabetes with a combination
Aardvarks
in
Diabetes Support
3 years ago
I am finding life difficult at the moment
Hello - I am due to go and see the nephrologist on the 28th to find out the results of my biopsy. I spoke to his secretary about my blood results and she said they were stable. they were reading 16.5. I am getting so worked up about this appointment I can't think of anything else - its like waiting to
Hello - I am due to go and see the nephrologist on the 28th to find out the results of my biopsy. I spoke to his secretary about my blood results and she said they were stable. they were reading 16.5. I am getting so worked up about this appointment I can't think of anything else - its like waiting to
fartikins
in
Kidney Disease
3 years ago
Carb cravings and - Muffins!
Just a short one. One of the problems with transitioning to a largely low carb high fat lifestyle is the inevitable craving for bread, potatoes, rice and pasta. When I was a child it was only bread and potatoes - pasta was largely unknown, and rice was a pudding. Anyway, many, many low carb recipes
Just a short one. One of the problems with transitioning to a largely low carb high fat lifestyle is the inevitable craving for bread, potatoes, rice and pasta. When I was a child it was only bread and potatoes - pasta was largely unknown, and rice was a pudding. Anyway, many, many low carb recipes
MikePollard
in
Low-Carb High-Fat (LCHF)
3 years ago
DHEA
I have been unwell for the last three years with terrible pains in my lags making painful to walk more than 10 meters with out a break. I thought it was something to do with T3 but I have pinpointed to using milk alturnatives ie Oak and coconut for some reason it affect the absorption of the t4. This
I have been unwell for the last three years with terrible pains in my lags making painful to walk more than 10 meters with out a break. I thought it was something to do with T3 but I have pinpointed to using milk alturnatives ie Oak and coconut for some reason it affect the absorption of the t4. This
stockman27
in
Thyroid UK
3 years ago
Self injecting B12
Hi wanted to ask which sites/companies are best to purchase B12 for self administration. Is it supplied in preloaded syringes or pens like insulin. Which brands, suppliers have given best results?
Hi wanted to ask which sites/companies are best to purchase B12 for self administration. Is it supplied in preloaded syringes or pens like insulin. Which brands, suppliers have given best results?
Polo22
in
Pernicious Anaemia Society
3 years ago
A positive post.
Hello everyone, I think I am ready to post some outcomes of my Armour + Levo treatment. I am still not quite there, but I have come a long way and need to write this to state that there is hope, that we can persevere almost anything and document improvements. I remember times only a few months ago
Hello everyone, I think I am ready to post some outcomes of my Armour + Levo treatment. I am still not quite there, but I have come a long way and need to write this to state that there is hope, that we can persevere almost anything and document improvements. I remember times only a few months ago
Incoguto
in
Thyroid UK
3 years ago
How to Increase BDNF
So somebody over on FB posted they were taking BDNF for PD anxiety (or maybe just for anxiety) so I Googled and found BDNF = Brain-Derived Neurotrophic Factor and BDNF supplements do not contain Brain-Derived Neurotrophic Factor. But I did find this article on strongcoffee.com. https://strongcoffeecompany.com
So somebody over on FB posted they were taking BDNF for PD anxiety (or maybe just for anxiety) so I Googled and found BDNF = Brain-Derived Neurotrophic Factor and BDNF supplements do not contain Brain-Derived Neurotrophic Factor. But I did find this article on strongcoffee.com. https://strongcoffeecompany.com
Bolt_Upright
in
Cure Parkinson's
3 years ago
Early Wake Up Back-To-Back
Good morning/afternoon/evening everyone. For
two (2) days back-to-back
, I had been
woken up with alarms going off from my CGM saying that I was under 80 mg/dl
. After doing a few tests using my strips/test kit's monitor, I had
2-3 6oz. cans of pineapple juice and protein shakes both
Good morning/afternoon/evening everyone. For
two (2) days back-to-back
, I had been
woken up with alarms going off from my CGM saying that I was under 80 mg/dl
. After doing a few tests using my strips/test kit's monitor, I had
2-3 6oz. cans of pineapple juice and protein shakes both
Activity2004
Administrator
in
Diabetes Research & Wellness Foundation
3 years ago
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