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Enzalutamide
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Orgovyx and enzalutamide
Can anyone tell me if Orgovyx and Xtandi are paid by Medicare Part B or the drug plan part D. If Part D, Is Wellcare a good plan to use?
Can anyone tell me if Orgovyx and Xtandi are paid by Medicare Part B or the drug plan part D. If Part D, Is Wellcare a good plan to use?
shihtzu124
in
Advanced Prostate Cancer
5 months ago
Second Line Hormonal
I have been trying to get my Oncologist to prescribe
Enzalutamide
. I have been treated with docetaxel again and thought it might re-sensitize me for another hormonal drug. Does anyone have any thoughts or experience with a situation like this.
I have been trying to get my Oncologist to prescribe
Enzalutamide
. I have been treated with docetaxel again and thought it might re-sensitize me for another hormonal drug. Does anyone have any thoughts or experience with a situation like this.
Islandboy2021
in
Advanced Prostate Cancer
26 days ago
Dual Action Hormone Therapy Targeting Two Parts of Androgen Receptor for mCRPC
Phase I/II trial of masofaniten combined with
enzalutamide
, a novel hormonal therapy for mCRPC. Masofaniten, a first-in-class N-terminal ligand antagonist for the androgen receptor, shows promise in overcoming resistance to current hormonal therapies. Hopefully a new weapon for us!
Phase I/II trial of masofaniten combined with
enzalutamide
, a novel hormonal therapy for mCRPC. Masofaniten, a first-in-class N-terminal ligand antagonist for the androgen receptor, shows promise in overcoming resistance to current hormonal therapies. Hopefully a new weapon for us!
Maxone73
in
Advanced Prostate Cancer
5 months ago
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RSI type symptoms to wrists and thumbs
Enzalutamide
stopped working. Had severe hyposensitivity reaction to docetaxel so looking at olaparib subject to gene testing. Coming off prednisalone gradually. Interested if anyone experienced similar issues with wrists and how long it lasted.
Enzalutamide
stopped working. Had severe hyposensitivity reaction to docetaxel so looking at olaparib subject to gene testing. Coming off prednisalone gradually. Interested if anyone experienced similar issues with wrists and how long it lasted.
FortyWinks
in
Advanced Prostate Cancer
2 days ago
European Society for Medical Oncology Congress - ESMO 2023 - Two Significant Lutetium Trials -mCRPC
This phase 2 randomised trial of
Enzalutamide
and Lu-PSMA-617, in poor risk mCRPC evaluated the activity and safety of combining
enzalutamide
with adaptive dosing of LuPSMA vs
enzalutamide
alone as first line treatment for mCRPC.
This phase 2 randomised trial of
Enzalutamide
and Lu-PSMA-617, in poor risk mCRPC evaluated the activity and safety of combining
enzalutamide
with adaptive dosing of LuPSMA vs
enzalutamide
alone as first line treatment for mCRPC.
marnieg46
in
Fight Prostate Cancer
6 months ago
Fenbendazole
He has been tinkering with different hormonal regimes, abiraterone and
enzalutamide
, without benefit, and has just progressed to start taking dexamethasone and is considering trying fenbendazole. I would be interested to hear of other peoples experience of fenbendazole ?
He has been tinkering with different hormonal regimes, abiraterone and
enzalutamide
, without benefit, and has just progressed to start taking dexamethasone and is considering trying fenbendazole. I would be interested to hear of other peoples experience of fenbendazole ?
Granolaloaf
in
Advanced Prostate Cancer
2 months ago
Reaction to docetaxel twice now.
My first line treatment was
Enzalutamide
for 3.5 years. Feeling a bit fed up but probably because I’m back to not knowing what happens next. many thanks
My first line treatment was
Enzalutamide
for 3.5 years. Feeling a bit fed up but probably because I’m back to not knowing what happens next. many thanks
FortyWinks
in
Advanced Prostate Cancer
21 days ago
No more enzalutamide: docetaxel next up
So
enzalutamide
has stopped doing its thing. PSA up to 3.9 but it’s worked for 3.5 years. Also got a new lesion in my thoracic spine so in addition to docetaxel, a single dose of radiotherapy. Hope that will all be underway within a couple of weeks.
So
enzalutamide
has stopped doing its thing. PSA up to 3.9 but it’s worked for 3.5 years. Also got a new lesion in my thoracic spine so in addition to docetaxel, a single dose of radiotherapy. Hope that will all be underway within a couple of weeks.
FortyWinks
in
Advanced Prostate Cancer
2 months ago
HELP WITH SIDE EFFECTS FROM ENZALUTAMIDE
I now want to discontinue taking
enzalutamide
. My PSA went down from 5.2 to 0.4 so the treatment is working it is just that the side effects are severely affecting my quality of life.
I now want to discontinue taking
enzalutamide
. My PSA went down from 5.2 to 0.4 so the treatment is working it is just that the side effects are severely affecting my quality of life.
Desrochers
in
Advanced Prostate Cancer
3 months ago
EMBARK Study: ADT vs Enzalutamide +/- ADT
The efficacy and safety of
enzalutamide
plus an- drogen-deprivation therapy and
enzalutamide
monotherapy, as compared with androgen-deprivation therapy alone, are unknown.
The efficacy and safety of
enzalutamide
plus an- drogen-deprivation therapy and
enzalutamide
monotherapy, as compared with androgen-deprivation therapy alone, are unknown.
MateoBeach
in
Advanced Prostate Cancer
6 months ago
EMBARK Study: Enzalutamide +/- ADT
The efficacy and safety of
enzalutamide
plus an- drogen-deprivation therapy and
enzalutamide
monotherapy, as compared with androgen-deprivation therapy alone, are unknown.
The efficacy and safety of
enzalutamide
plus an- drogen-deprivation therapy and
enzalutamide
monotherapy, as compared with androgen-deprivation therapy alone, are unknown.
MateoBeach
in
Fight Prostate Cancer
6 months ago
Testosterone was nearly back to normal, then dropped
I had a year of Lupron and
Enzalutamide
in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal?
I had a year of Lupron and
Enzalutamide
in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal?
Teddy28
in
Advanced Prostate Cancer
3 months ago
Masofaniten +Enzalutamide This could be a game changer...Science is coming to our aid
Masofaniten has no effect on
enzalutamide
exposure, thus allowing the use of full dose per label (160mg) of
enzalutamide
in combination.
Masofaniten has no effect on
enzalutamide
exposure, thus allowing the use of full dose per label (160mg) of
enzalutamide
in combination.
Scout4answers
in
Advanced Prostate Cancer
6 months ago
Cabazitaxel or Phase 1 drug trial
RP 2008, Bicalutimide 2008 until 2019,
Enzalutamide
2019 - 2022, Zoladex 3 monthly implant 2019 ongoing. Phase 1 drug trial at Royal Marsden in London Jan 2023 - June 2023 (failed). Doxetaxel August 2023 - November 2023 - but gave up after 5 infusion as it was clearly not working.
RP 2008, Bicalutimide 2008 until 2019,
Enzalutamide
2019 - 2022, Zoladex 3 monthly implant 2019 ongoing. Phase 1 drug trial at Royal Marsden in London Jan 2023 - June 2023 (failed). Doxetaxel August 2023 - November 2023 - but gave up after 5 infusion as it was clearly not working.
Petertanner
in
Advanced Prostate Cancer
4 months ago
phase 2 study for mCRPC
https://www.uclahealth.org/clinical-trials/study-two-dose-levels-vobramitamab-duocarmazine-participants For people previously treated with apalutamide, darolutamide,
enzalutamide
, abiraterone It’s and ADC targeting B7-H3 checkpoint https://clinicaltrials.gov/study/NCT05032040 Targets PD1
https://www.uclahealth.org/clinical-trials/study-two-dose-levels-vobramitamab-duocarmazine-participants For people previously treated with apalutamide, darolutamide,
enzalutamide
, abiraterone It’s and ADC targeting B7-H3 checkpoint https://clinicaltrials.gov/study/NCT05032040 Targets PD1
Maxone73
in
Advanced Prostate Cancer
7 months ago
Mark Buckley
Standing
Enzalutamide
4 tablets daily. 19th September 2023. Started Tamsulosia Hydrochloride 23rd September 2023. 1 x tablet daily.
Standing
Enzalutamide
4 tablets daily. 19th September 2023. Started Tamsulosia Hydrochloride 23rd September 2023. 1 x tablet daily.
whatisontheriver
in
Advanced Prostate Cancer
5 months ago
Father’s CRPCa Failed chemo (Cabazitaxel,Docetaxel) and Failed LU177
Failed Drug vacation 2023 July to 2023 September - PSA rose to 269. 2023 Sep - 2023 Nov
Enzalutamide
Ineffective … and stopped due to severe side effects. 2023 Dec PSA increased to 357. Started Cabazitaxel on December 27, 2023. 2nd dose on January 16th, 2024 and 3rd dose on February 6th, 2024.
Failed Drug vacation 2023 July to 2023 September - PSA rose to 269. 2023 Sep - 2023 Nov
Enzalutamide
Ineffective … and stopped due to severe side effects. 2023 Dec PSA increased to 357. Started Cabazitaxel on December 27, 2023. 2nd dose on January 16th, 2024 and 3rd dose on February 6th, 2024.
Vishwa1890
in
Advanced Prostate Cancer
2 months ago
Good news for mCRPC (hopefully), phase 2
And here we go: "mCRPC patients who have relapsed or are refractory to androgen receptor signalling inhibitors (ARSIs) such as apalutamide, darolutamide, abiraterone and
enzalutamide
are included in the study." https://www.clinicaltrialsarena.com/news/oncternal-patient-prostate-cancer/
And here we go: "mCRPC patients who have relapsed or are refractory to androgen receptor signalling inhibitors (ARSIs) such as apalutamide, darolutamide, abiraterone and
enzalutamide
are included in the study." https://www.clinicaltrialsarena.com/news/oncternal-patient-prostate-cancer/
Maxone73
in
Advanced Prostate Cancer
7 months ago
ADT 's effect on body fat and muscle mass from Life on ADT blog by Richard Wassersug
It turns out that adding abiraterone to standard ADT increases the diabetic risk slightly, while adding
enzalutamide
reduces that risk for some men on ADT. This can be partly understood by changes in the androgen receptor, which is targeted by
enzalutamide
.
It turns out that adding abiraterone to standard ADT increases the diabetic risk slightly, while adding
enzalutamide
reduces that risk for some men on ADT. This can be partly understood by changes in the androgen receptor, which is targeted by
enzalutamide
.
Scout4answers
in
Advanced Prostate Cancer
6 months ago
Anyone tried cabazitaxel (Jevtana) monotherapy?
I'm also thinking about taking
enzalutamide
(Xtandi) [u]after[/u] the cabazitaxel if I still have detectable PSA. Thanks in advance.
I'm also thinking about taking
enzalutamide
(Xtandi) [u]after[/u] the cabazitaxel if I still have detectable PSA. Thanks in advance.
ron_bucher
in
Advanced Prostate Cancer
5 months ago
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