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Experiences with
Denosumab
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Prolio SE
Two questions: 1) The SE are VERY SCARY when I read this: https://www.drugs.com/comments/
denosumab
/prolia.html But, then again, uneventful outcome folks are not likely to post. Sooo... what has been your SE experience? 2) Never had a subcutaneous shot so what's that like? Mel
Two questions: 1) The SE are VERY SCARY when I read this: https://www.drugs.com/comments/
denosumab
/prolia.html But, then again, uneventful outcome folks are not likely to post. Sooo... what has been your SE experience? 2) Never had a subcutaneous shot so what's that like? Mel
compiler
in
Advanced Prostate Cancer
10 months ago
CR Advanced Prostrate Ca, and start of chemotherapy after PSMA
[/i] He does not have any bone pain in the body as of now.He has been given Docetaxal 120 infusion alongwith
Denosumab
120 injection for bones.
[/i] He does not have any bone pain in the body as of now.He has been given Docetaxal 120 infusion alongwith
Denosumab
120 injection for bones.
Ij2023
in
Advanced Prostate Cancer
5 months ago
PMR Review with GP
Could it be
Denosumab
? I need to follow up and check what it was. It might be on my notes. I made it clear that I wouldn't have anything that might prevent me from having dental treatment and that I had never had a DEXA scan.
Could it be
Denosumab
? I need to follow up and check what it was. It might be on my notes. I made it clear that I wouldn't have anything that might prevent me from having dental treatment and that I had never had a DEXA scan.
Gimme
in
PMRGCAuk
2 months ago
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Cabazitaxel and estrogen patch
Denosumab
and Zoledronic acid don't work for him. I suggested an Estrogen patch to both maintain bone density and ameliorate hot flashes. His oncologist said that an Estrogen patch would interfere with the Cabazitaxel. I can't find any literature in the subject.
Denosumab
and Zoledronic acid don't work for him. I suggested an Estrogen patch to both maintain bone density and ameliorate hot flashes. His oncologist said that an Estrogen patch would interfere with the Cabazitaxel. I can't find any literature in the subject.
DCDan
in
Advanced Prostate Cancer
11 months ago
Risedronate Sodium v Denosumab (Prolia)
I have read that if you stop taking prolia, you can get rebound effects. Is this also true with Risedronate ? I am still in a deliberating which to take (if any) Thanks
I have read that if you stop taking prolia, you can get rebound effects. Is this also true with Risedronate ? I am still in a deliberating which to take (if any) Thanks
Calamintha
in
Bone Health and Osteoporosis UK
11 months ago
Where to go after Lutetium 177?
Because of jaw numbness, the oncologists ceased his once per month
Denosumab
about 3 months ago. Jaw has slightly improved, but no one seems to know if the cause is
Denosumab
or the Hep E that we contracted, or something else.
Because of jaw numbness, the oncologists ceased his once per month
Denosumab
about 3 months ago. Jaw has slightly improved, but no one seems to know if the cause is
Denosumab
or the Hep E that we contracted, or something else.
Biobro
in
Advanced Prostate Cancer
10 months ago
SBRT to Prostate and Lymph node ?
Since then he has been on ADT + Enza +
Denosumab
regimen (details on my profile) His PSA had increased slightly in the last few readings but he has largely been asymptomatic 12/22 - 0.81 03/23 - 0.83 06/23 - 1.21 Based on the above our Oncologist suggested a PSMA scan and a repeat of PSA test
Since then he has been on ADT + Enza +
Denosumab
regimen (details on my profile) His PSA had increased slightly in the last few readings but he has largely been asymptomatic 12/22 - 0.81 03/23 - 0.83 06/23 - 1.21 Based on the above our Oncologist suggested a PSMA scan and a repeat of PSA test
dudubaya
in
Advanced Prostate Cancer
10 months ago
Told that I can’t have Zoledronic Acid.
I’ve previously had a severe reaction to
Denosumab
, so I’m getting very low on options. I am truly grateful that my hospital has my best interests at heart Literally! Any thoughts or advice gratefully received! X 👼🏻❤️🙏🏻X
I’ve previously had a severe reaction to
Denosumab
, so I’m getting very low on options. I am truly grateful that my hospital has my best interests at heart Literally! Any thoughts or advice gratefully received! X 👼🏻❤️🙏🏻X
Angelicspirit
in
Bone Health and Osteoporosis UK
11 months ago
Fever after the monthly degarelix shot
Hi All, My father has his degarelix and
denosumab
subcutaneous injections every 4 weeks as prescribed. Of late he has started getting fevers in the night on the day of the shot. The fever usually lasts for a day and resolves on its own.
Hi All, My father has his degarelix and
denosumab
subcutaneous injections every 4 weeks as prescribed. Of late he has started getting fevers in the night on the day of the shot. The fever usually lasts for a day and resolves on its own.
dudubaya
in
Advanced Prostate Cancer
1 year ago
Denosomab and Dental Treatment
To my surprise, the hospital notified my dentist that there was no need for me to have the extractions in a hospital as problems with
Denosumab
were very rare and did not merit hospitalisation.
To my surprise, the hospital notified my dentist that there was no need for me to have the extractions in a hospital as problems with
Denosumab
were very rare and did not merit hospitalisation.
bienassis
in
NRAS
1 year ago
living well with a ticking time bomb
This is how I feel with widespread bone metastasis to my bones. however with degarelix ,abiraterone and
denosumab
for bone strength I now go through life as I did before. but for how long ?
This is how I feel with widespread bone metastasis to my bones. however with degarelix ,abiraterone and
denosumab
for bone strength I now go through life as I did before. but for how long ?
yardsailor
in
Cancer Thrivers
1 year ago
Dexa Scan
They are suggesting
Denosumab
or Zoledrante. My total spinal T score is -2.4 from -2.0, Neck of Femur is -2 from -1.6, and total hip is -0.6 from -0.4. I take Adcal and try to have a good diet. I don’t want to take anything else and any advice how to deal with the Dr on this is appreciated
They are suggesting
Denosumab
or Zoledrante. My total spinal T score is -2.4 from -2.0, Neck of Femur is -2 from -1.6, and total hip is -0.6 from -0.4. I take Adcal and try to have a good diet. I don’t want to take anything else and any advice how to deal with the Dr on this is appreciated
Booklover21
in
PMRGCAuk
3 months ago
Bone Health issues re:Bisphosphonnates, etc. ????
I'm back again for further research about the bone density medications, and now wondering about the use of bisphosphonates,
denosumab
and teriparatide? My PCP is suggesting these, but he's not current with the research about estrogen and testosterone use for PCa care.
I'm back again for further research about the bone density medications, and now wondering about the use of bisphosphonates,
denosumab
and teriparatide? My PCP is suggesting these, but he's not current with the research about estrogen and testosterone use for PCa care.
ragnar2020
in
Fight Prostate Cancer
1 year ago
Collagen Peptide supplements and bone quality
There are a series of things that can be done -- 1, Get a DEX scan now 2, Supplement with Calcium, K2, D3 and magnesium 3, Have your MO or whoever put you on BMD medication (eg
denosumab
, et al) Now comes the question.
There are a series of things that can be done -- 1, Get a DEX scan now 2, Supplement with Calcium, K2, D3 and magnesium 3, Have your MO or whoever put you on BMD medication (eg
denosumab
, et al) Now comes the question.
Derf4223
in
Advanced Prostate Cancer
1 year ago
Dry Mouth & the Advanced PC Patient (for those on Pluvicto or meds or ICI, where a side effect is dry mouth) - A Guide
Drugs such as zoledronic acid (Zometa),
denosumab
(Prolia or Xgeva) and IV bisphosphonates can be effective, but come with an increased risk for osteonecrosis of the jaw (ONJ). ONJ occurs when cells in the jaw bone die and the body tries to rid itself of the dead bone.
Drugs such as zoledronic acid (Zometa),
denosumab
(Prolia or Xgeva) and IV bisphosphonates can be effective, but come with an increased risk for osteonecrosis of the jaw (ONJ). ONJ occurs when cells in the jaw bone die and the body tries to rid itself of the dead bone.
rsgdmd
in
Advanced Prostate Cancer
11 months ago
xgeva/Denosumab
I am stable and still on my 1st line of treatment which is Palbociclib 75mg, letrozole,
denosumab
and zoladex. Because of low neutrophils I am on a 6 wk cycle, 3weeks on 3 weeks off, with the
denosumab
being 6 weekly inline with the other treatment which I administer myself.
I am stable and still on my 1st line of treatment which is Palbociclib 75mg, letrozole,
denosumab
and zoladex. Because of low neutrophils I am on a 6 wk cycle, 3weeks on 3 weeks off, with the
denosumab
being 6 weekly inline with the other treatment which I administer myself.
Crazycocker
in
SHARE Metastatic Breast Cancer
1 year ago
Osteoporosis and Men (risks, fractures and support)
campaign=77a866ee-c708-ed11-82e5-0022481b5a28 What you need to know about osteoporosis and prostate cancer: https://youtu.be/pGGO6xPQnL0 #men #osteoporosis #prostate #steroid #alendronate #zoledronate #Teriparatide #
denosumab
#drugtreatment #Klinefelters #testosterone
campaign=77a866ee-c708-ed11-82e5-0022481b5a28 What you need to know about osteoporosis and prostate cancer: https://youtu.be/pGGO6xPQnL0 #men #osteoporosis #prostate #steroid #alendronate #zoledronate #Teriparatide #
denosumab
#drugtreatment #Klinefelters #testosterone
ROSModerator
Partner
in
Bone Health and Osteoporosis UK
10 months ago
Recent paper on osteonecrosis of the jaw - some extracts relevant for PCa patients are given below
Medication That Can Cause MRONJ “Medication that can cause MRONJ can be divided into antiresorptive drugs, which include bisphosphonates and
denosumab
, and antiangiogenic drugs [20]. Bisphosphonates are analogs of pyrophosphate, a natural inhibitor of bone metabolism.
Medication That Can Cause MRONJ “Medication that can cause MRONJ can be divided into antiresorptive drugs, which include bisphosphonates and
denosumab
, and antiangiogenic drugs [20]. Bisphosphonates are analogs of pyrophosphate, a natural inhibitor of bone metabolism.
Graham49
in
Advanced Prostate Cancer
1 year ago
denosumab injections
I would be particularly interested and grateful hearing from people who also had bad reactions to AA, but then were subsequently ok with
denosumab
, and if anyone has stopped the
denosumab
, what happened with the “coming down” treatment.
I would be particularly interested and grateful hearing from people who also had bad reactions to AA, but then were subsequently ok with
denosumab
, and if anyone has stopped the
denosumab
, what happened with the “coming down” treatment.
Calamintha
in
Bone Health and Osteoporosis UK
1 year ago
A Different View on Bone Protection
The lower dose of
denosumab
, Prolia every six months seems a reasonable conservative approach. Along with regular dental hygiene and care. Also, after some years on
denosumab
, when it is stopped ther can be some rebound drop in bone density.
The lower dose of
denosumab
, Prolia every six months seems a reasonable conservative approach. Along with regular dental hygiene and care. Also, after some years on
denosumab
, when it is stopped ther can be some rebound drop in bone density.
MateoBeach
in
Fight Prostate Cancer
1 year ago
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