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5 months after stopping the 4 mos of taking orgovyx still very symptomatic of low t (miserable)..told t may never recover (79),take trt? ?
Stopped taking 4 months of orgovyx may 28th. It is now 5 months after stop taking pills. Still very symptomatic of low t, (i.e. fatigue getting worse,(tired as hell) , cognitive issues getting worse, weight gain, (exercising but still), joint aches, sugars climbing...MISERABLE. need my life back..
Stopped taking 4 months of orgovyx may 28th. It is now 5 months after stop taking pills. Still very symptomatic of low t, (i.e. fatigue getting worse,(tired as hell) , cognitive issues getting worse, weight gain, (exercising but still), joint aches, sugars climbing...MISERABLE. need my life back..
JWS13
in
Advanced Prostate Cancer
6 months ago
Metastasized to Bones
I have been seeing post saying poeple being diagnosed with metastasized PC. I was diagnosed with PC metastasized to my bones, after being under urologist care for 18 months I am wondering if poeple who get initially diagnosed with metastasized PC, whether it is because they were not under medical care
I have been seeing post saying poeple being diagnosed with metastasized PC. I was diagnosed with PC metastasized to my bones, after being under urologist care for 18 months I am wondering if poeple who get initially diagnosed with metastasized PC, whether it is because they were not under medical care
hopefull99
in
Advanced Prostate Cancer
6 months ago
MOST RECENT PSA and TESTOSTERONE TEST
My PSA and testosterone test results have been PSA .01 and T 11 since July of 2022. I had my quarterly test done yesterday and my PSA is at .02 and T is at 21.5. They are still undetectable, but not sure what caused the rise. I've only been on Firmagon for 1 year and 4 months so I hope it doesn't
My PSA and testosterone test results have been PSA .01 and T 11 since July of 2022. I had my quarterly test done yesterday and my PSA is at .02 and T is at 21.5. They are still undetectable, but not sure what caused the rise. I've only been on Firmagon for 1 year and 4 months so I hope it doesn't
GMan-62
in
Advanced Prostate Cancer
6 months ago
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seeking feedback on my case
hi, hoping Tall_Allen and anyone else may have some thoughts...... I posted several mos. ago after being diagnosed with distant only metastatic -- GL7, low PSA, thought to be contained and headed for surgery, but asked for a PSMA -- showed 8-10 lesions in ribs and scapula. Mostly low SUV. Diagnosis
hi, hoping Tall_Allen and anyone else may have some thoughts...... I posted several mos. ago after being diagnosed with distant only metastatic -- GL7, low PSA, thought to be contained and headed for surgery, but asked for a PSMA -- showed 8-10 lesions in ribs and scapula. Mostly low SUV. Diagnosis
tmscat
in
Advanced Prostate Cancer
6 months ago
Current advances of liquid biopsies in prostate cancer: Molecular biomarkers, Cell/Molecular Therapy Oncolytics, 09/21/23
Recent comprehensive paper on the use of liquid biopsies for diagnosis and treatment of PCa. Comprehensive summary tables are provided for both purposes. From the paper: [i]Introduction[/i] [i]The prostate-specific antigen (PSA) test is one of the most widely used screening tests for men at risk for
Recent comprehensive paper on the use of liquid biopsies for diagnosis and treatment of PCa. Comprehensive summary tables are provided for both purposes. From the paper: [i]Introduction[/i] [i]The prostate-specific antigen (PSA) test is one of the most widely used screening tests for men at risk for
CaptnMojoe
in
Fight Prostate Cancer
6 months ago
Provenge Underway
Morning folks, Well I completed my first cycle of Provenge yesterday and all seems well so far. I also met with MO to review recent genetic testing results and have confirmed a mutation BRiP1 which is associated with autosomal dominant hereditary ovarian cancer, autosomal recessive Fanconia anemia,
Morning folks, Well I completed my first cycle of Provenge yesterday and all seems well so far. I also met with MO to review recent genetic testing results and have confirmed a mutation BRiP1 which is associated with autosomal dominant hereditary ovarian cancer, autosomal recessive Fanconia anemia,
Pmann
in
Advanced Prostate Cancer
6 months ago
ADT + Zytiga holiday???
I've been on Orgovyx since 8/15/22 and Zytiga since 4/1/23. I'm also suffering from neuropathy from nerve damage that occurred in December 22. The nerve pain has gotten worse and my oncologist and neurologist are wondering if ADT or Zytiga are too blame. Anyone have experience with these drugs and
I've been on Orgovyx since 8/15/22 and Zytiga since 4/1/23. I'm also suffering from neuropathy from nerve damage that occurred in December 22. The nerve pain has gotten worse and my oncologist and neurologist are wondering if ADT or Zytiga are too blame. Anyone have experience with these drugs and
VanHalen84
in
Advanced Prostate Cancer
6 months ago
New meta-analysis shows docetaxel benefits those having high grade/low PSA prostate cancer
Reposting with more specific title - no one had replied to Maxone73's original post. Interesting results for those with a poor-prognosis cancer. https://www.miragenews.com/docetaxel-slashes-prostate-cancer-death-in-high-1115466/
Reposting with more specific title - no one had replied to Maxone73's original post. Interesting results for those with a poor-prognosis cancer. https://www.miragenews.com/docetaxel-slashes-prostate-cancer-death-in-high-1115466/
HikerWife
in
Advanced Prostate Cancer
6 months ago
Docetaxel only partially successful
I had a full body MRI scan this week at Royal Marsden in London. The purpose was to assess the effectiveness of docetaxel after 3 infusions. The results have been very disappointing, and I'm struggling to keep a sense of perspective - not least because I was feeling so good, and had seen all of my previous
I had a full body MRI scan this week at Royal Marsden in London. The purpose was to assess the effectiveness of docetaxel after 3 infusions. The results have been very disappointing, and I'm struggling to keep a sense of perspective - not least because I was feeling so good, and had seen all of my previous
CrocodileShoes
in
Advanced Prostate Cancer
6 months ago
tumor in spleen
my husband is having his spleen out very soon due to 2 tumors. We won’t know for sure if they are cancer until pathology done. He had radiation plus Lupron and has been in remission 2 years. 4 + 4 Psa still non detectable. Tumors picked up on pet scan to check kidney. Radiologist has said rare
my husband is having his spleen out very soon due to 2 tumors. We won’t know for sure if they are cancer until pathology done. He had radiation plus Lupron and has been in remission 2 years. 4 + 4 Psa still non detectable. Tumors picked up on pet scan to check kidney. Radiologist has said rare
Ojsm
in
Advanced Prostate Cancer
6 months ago
ONCT-534 Earns FDA Fast Track Designation in R/R Metastatic CRPC
Looks like a number of Drug companies are creating drugs that interact with the AR’s N-terminal domain and ligand-binding domain, impeding cell growth and enabling AR degradation. ONCT-534 Earns FDA Fast Track Designation in R/R Metastatic CRPC October 27, 2023 Investigators will assess
Looks like a number of Drug companies are creating drugs that interact with the AR’s N-terminal domain and ligand-binding domain, impeding cell growth and enabling AR degradation. ONCT-534 Earns FDA Fast Track Designation in R/R Metastatic CRPC October 27, 2023 Investigators will assess
Scout4answers
in
Advanced Prostate Cancer
6 months ago
PSMA PET scan
Hello everyone, pardon the simplicity of my question. Is PSMA the same as PET Scan? I ask this because I specifically asked my MO to have a PSMA pet scam but no where in the order or appointment a mention of PSMA pet scan it only says pet scan. I am concerned because MO doesn't seem to be very involved
Hello everyone, pardon the simplicity of my question. Is PSMA the same as PET Scan? I ask this because I specifically asked my MO to have a PSMA pet scam but no where in the order or appointment a mention of PSMA pet scan it only says pet scan. I am concerned because MO doesn't seem to be very involved
Blueribbon63
in
Advanced Prostate Cancer
6 months ago
castration after 7 years of ADT
I have been on Zoladex for nearly 7 years and am fully over any regrets of Chemical castration. My psa is now slowly rising and ghastly taken 2 years from undetectable to 0.65. I am considering surgical castration now as it would mean no more 3 monthly Zoladex injections and a reduced chemical load on
I have been on Zoladex for nearly 7 years and am fully over any regrets of Chemical castration. My psa is now slowly rising and ghastly taken 2 years from undetectable to 0.65. I am considering surgical castration now as it would mean no more 3 monthly Zoladex injections and a reduced chemical load on
Roscoaus2000
in
Advanced Prostate Cancer
6 months ago
Is my cancer castrate resistant?
Since detection of abdominal and pelvic mesastasis by PSMA scan in October 2018, intermittant Lupron was very effective in keeping my cancer under control until July 2022. From July 2022 until now I have been on continuous Lupron because PSA refused to become undetectable. From July 2022 until August
Since detection of abdominal and pelvic mesastasis by PSMA scan in October 2018, intermittant Lupron was very effective in keeping my cancer under control until July 2022. From July 2022 until now I have been on continuous Lupron because PSA refused to become undetectable. From July 2022 until August
dac500
in
Advanced Prostate Cancer
6 months ago
Pluvicto Failed - Next step
Hello Warriors: Pluvicto has failed. I went through four sessions and had severe side effects of exhaustion and GI problems as well as it seemed to stimulate my foot neuropathy. My PSA went down during injection 2 and 3 but then came back up in 4. Disappointing... I just met my new MO at the Mayo
Hello Warriors: Pluvicto has failed. I went through four sessions and had severe side effects of exhaustion and GI problems as well as it seemed to stimulate my foot neuropathy. My PSA went down during injection 2 and 3 but then came back up in 4. Disappointing... I just met my new MO at the Mayo
Hidden
in
Advanced Prostate Cancer
6 months ago
Cavernous Tumor & Rising PSA
My husband had triple therapy with docetaxel (finished chemo in January), darolutimide, and Firmagon/Lupron. Recently he developed what seemed like a sinus infection but was really a tumor in his sinus cavity and behind his eye socket wrapped around his carotid arteries on the plate of his skull (
My husband had triple therapy with docetaxel (finished chemo in January), darolutimide, and Firmagon/Lupron. Recently he developed what seemed like a sinus infection but was really a tumor in his sinus cavity and behind his eye socket wrapped around his carotid arteries on the plate of his skull (
Izzygirl1
in
Advanced Prostate Cancer
6 months ago
Relugolix and Apalutamide
Any experience with elevated AST and ALT after being treated with Relugolix and Apalutamide? My AST and ALT were normal on Relugolix for 6 weeks.....added Apalutamide and after 4 weeks my AST and ALT are now 3X previous level. I feel fine. Oncologist is wanting to stop the one of the drugs.....I convinced
Any experience with elevated AST and ALT after being treated with Relugolix and Apalutamide? My AST and ALT were normal on Relugolix for 6 weeks.....added Apalutamide and after 4 weeks my AST and ALT are now 3X previous level. I feel fine. Oncologist is wanting to stop the one of the drugs.....I convinced
GoLowPSA
in
Advanced Prostate Cancer
6 months ago
What a long strange road it's been.
Nov 2007 I had DaVinci surgery Gleason 7. I got the surgeon's notes and he said margins were clear, took s bunch of lymph glands, all clear. Held my dick in his hand and said it would come back. It did, but never quite lost the "happy bladder" and I shot pee about 50% of the time. PSA never went
Nov 2007 I had DaVinci surgery Gleason 7. I got the surgeon's notes and he said margins were clear, took s bunch of lymph glands, all clear. Held my dick in his hand and said it would come back. It did, but never quite lost the "happy bladder" and I shot pee about 50% of the time. PSA never went
bcskibdy
in
Prostate Cancer And Gay Men
6 months ago
Side effects experienced once you add Zytiga to Orgovyx
My husband, age 73, is diagnosed with very high risk prostate cancer, Gleason 9, PSA 46.6 and being treated ay Mayo, Phoenix. He is almost done with 28 Proton Radiation treatments, was on Casodex a few weeks then started Orgovyx.( at least two years recommended) He is considering adding Zytiga. He
My husband, age 73, is diagnosed with very high risk prostate cancer, Gleason 9, PSA 46.6 and being treated ay Mayo, Phoenix. He is almost done with 28 Proton Radiation treatments, was on Casodex a few weeks then started Orgovyx.( at least two years recommended) He is considering adding Zytiga. He
CancerConcierge
in
Advanced Prostate Cancer
6 months ago
Update: PSA after IMRT
After my 40 treatments, I wanted to get off the bicalutamide I had been on for 2 months. My breasts had not only gotten enlarged but they had also become quite painful, and the Tamoxifen my RO had put me on did not help with this. He then ordered an early PSA test, and when it came back at just .12
After my 40 treatments, I wanted to get off the bicalutamide I had been on for 2 months. My breasts had not only gotten enlarged but they had also become quite painful, and the Tamoxifen my RO had put me on did not help with this. He then ordered an early PSA test, and when it came back at just .12
Smarks42
in
Prostate Cancer Network
6 months ago
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