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Androgen deprivation therapy (ADT)
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What exactly causes my hot flashes.
I know WHY they happen,
ADT
. I'd like to know what is going on in my body to cause them. Also, as long as you PSA is 'unmeasurable', does that, in itself, mean that your cancer has NOT metastasized? Or are there other tests that I should be doing? Thanks. dixiedad and ROLL TIDE!
I know WHY they happen,
ADT
. I'd like to know what is going on in my body to cause them. Also, as long as you PSA is 'unmeasurable', does that, in itself, mean that your cancer has NOT metastasized? Or are there other tests that I should be doing? Thanks. dixiedad and ROLL TIDE!
dixiedad
in
Advanced Prostate Cancer
1 year ago
Post-SRT/ADT PSA Monitoring
The initial substantial decrease in my PSA was attributed pretty much exclusively to the
ADT
, but as the
ADT
dose wears off, would it be reasonable to expect the increase in my PSA before the SRT fully kicks in? Or am I just completely out to lunch and need to be more concerned than I am?
The initial substantial decrease in my PSA was attributed pretty much exclusively to the
ADT
, but as the
ADT
dose wears off, would it be reasonable to expect the increase in my PSA before the SRT fully kicks in? Or am I just completely out to lunch and need to be more concerned than I am?
dans_journey
in
Advanced Prostate Cancer
1 year ago
Prostate cancer treatment and sexual mutilation
Well well. In the midst of the club no one wants to be a part of and just wanted to add my input. It seems that the treatment of prostate cancer often glazes over the fact that you will be sexually impacted severely. Depending on treatment outcome that could be a 0 to 7. Seems like the topic isn’t really
Well well. In the midst of the club no one wants to be a part of and just wanted to add my input. It seems that the treatment of prostate cancer often glazes over the fact that you will be sexually impacted severely. Depending on treatment outcome that could be a 0 to 7. Seems like the topic isn’t really
Yokohama2023
in
Advanced Prostate Cancer
3 months ago
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Back in permanent AF and warfarin dose decrease
Hi All, I used to have paroxysmal AF which was ablated by Prof Schilling back in 2010. I had been in NSR. However I was diagnosed with prostate cancer back in the summer. I had huge delays and postponements before I had a biopsy. I eventually got the results 5 weeks later (rather than the two weeks promised
Hi All, I used to have paroxysmal AF which was ablated by Prof Schilling back in 2010. I had been in NSR. However I was diagnosed with prostate cancer back in the summer. I had huge delays and postponements before I had a biopsy. I eventually got the results 5 weeks later (rather than the two weeks promised
MarkS
in
AF Association
3 months ago
BAT Question
I would like to know for those folks experimenting with BAT or actively doing so with their MO once your T rises again and then when you reinitiate
ADT
do you go through the whole hot flash cycle again? Is it the constant back and forth feeling of feeling great and then like crap?
I would like to know for those folks experimenting with BAT or actively doing so with their MO once your T rises again and then when you reinitiate
ADT
do you go through the whole hot flash cycle again? Is it the constant back and forth feeling of feeling great and then like crap?
watertender
in
Advanced Prostate Cancer
1 year ago
Is the a standard/preferred course of treatment for mixed ductal PC (post- RALP, post recurrence in prostate bed, post radiation)?
I’m also a tiny bit concerned about the psa reading.. was expecting <0.2… I know 0.4 is not huge, but after 3 months of
ADT
and a full course of radiation, I would have thought undetectable was likely. Thanks for any info!
I’m also a tiny bit concerned about the psa reading.. was expecting <0.2… I know 0.4 is not huge, but after 3 months of
ADT
and a full course of radiation, I would have thought undetectable was likely. Thanks for any info!
Caldonia
in
Advanced Prostate Cancer
1 year ago
Blood tests to monitor while on ADT..etc
Hi, Currently, on
ADT
, I'm about four months in on Lupron of an 18-month prescription. Trying to do all the right things (diet/exercise.e.tc).
Hi, Currently, on
ADT
, I'm about four months in on Lupron of an 18-month prescription. Trying to do all the right things (diet/exercise.e.tc).
SierraSix
in
Advanced Prostate Cancer
1 year ago
Side effects of Relvar Ellipta?
Hi, I have been on Relvar Ellipta for, I think, four years now. It works well to control my asthma, but I wonder if anybody has got any side effects from this medicine? Apart from asthma, I have problems with a heart valve (Mitral), and I am hormone treatment for prostate cancer, and also I take Budesonide
Hi, I have been on Relvar Ellipta for, I think, four years now. It works well to control my asthma, but I wonder if anybody has got any side effects from this medicine? Apart from asthma, I have problems with a heart valve (Mitral), and I am hormone treatment for prostate cancer, and also I take Budesonide
crille
in
Asthma Community Forum
3 months ago
How soon after taking 4 month eligard shot can you switch to firmagon?
I started my hormone treatment with firmagon + apalutamide beginning 2023. The treatment worked fantastic and all my pain faded away and my psa dropped from 350 to .09 over 11 months. My life was as near normal as can be expected with cancer. Almost immediately my MO was recomending to switch to 4
I started my hormone treatment with firmagon + apalutamide beginning 2023. The treatment worked fantastic and all my pain faded away and my psa dropped from 350 to .09 over 11 months. My life was as near normal as can be expected with cancer. Almost immediately my MO was recomending to switch to 4
skiingfiend
in
Advanced Prostate Cancer
3 months ago
Overwhelmed, what do I do next? Mutations In my Germline & a Tier 1 ATM Frameshift Alteration
My Germline is I’m missing a blm copy like a bloom syndrome drop My Genomic Tier 1 is a ATM Frameshift Alteration I have a battery of mutations listed in my profile bio. My PSA in the last 4 months is rising from <0.06 in October to 0.46 last week. I’m on Firmagon monthly, Zytiga with Prednisone
My Germline is I’m missing a blm copy like a bloom syndrome drop My Genomic Tier 1 is a ATM Frameshift Alteration I have a battery of mutations listed in my profile bio. My PSA in the last 4 months is rising from <0.06 in October to 0.46 last week. I’m on Firmagon monthly, Zytiga with Prednisone
Shorehousejam
in
Advanced Prostate Cancer
3 months ago
Treatment Options
PSA 4.7 (over 2 years it double and then doubled again) This is the Pathology report A: Prostate gland, left lateral posterior, biopsy: Benign prostatic tissue with mild chronic inflammation, no tumor present. B: Prostate gland, left lateral mid, biopsy: Benign prostatic tissue with mild chronic
PSA 4.7 (over 2 years it double and then doubled again) This is the Pathology report A: Prostate gland, left lateral posterior, biopsy: Benign prostatic tissue with mild chronic inflammation, no tumor present. B: Prostate gland, left lateral mid, biopsy: Benign prostatic tissue with mild chronic
Vortex12
in
Prostate Cancer Network
3 months ago
Follow up to "My trajectory after a 'vacation' and a new metastasis," and a new question
I though that the recommendation of the "tumor board" at Smilow Cancer Center in New Haven, CT, would be "doublet therapy" to treat the new metastasis that was found with a PET PSMA scan, (the second one that was found after my Lupron "vacation"; the first was treated with radiation--details of my case
I though that the recommendation of the "tumor board" at Smilow Cancer Center in New Haven, CT, would be "doublet therapy" to treat the new metastasis that was found with a PET PSMA scan, (the second one that was found after my Lupron "vacation"; the first was treated with radiation--details of my case
Istomin
in
Advanced Prostate Cancer
3 months ago
8 Month Follow up Report from Lu-J591
In 2014 my PSA was over 5.0 and went on bicalutamide + dutasteride as alternative
ADT
. Positive PLNs on PSMA in 2019 led to hemipelvic SRT and 6 months
ADT
. However, PSA rising in 2021 to 0.20 and repeat PSMA PET showed recurrence in two new LN sites, one para-aortic, so now metastatic.
In 2014 my PSA was over 5.0 and went on bicalutamide + dutasteride as alternative
ADT
. Positive PLNs on PSMA in 2019 led to hemipelvic SRT and 6 months
ADT
. However, PSA rising in 2021 to 0.20 and repeat PSMA PET showed recurrence in two new LN sites, one para-aortic, so now metastatic.
MateoBeach
in
Fight Prostate Cancer
1 year ago
Collagen Peptide supplements and bone quality
Y'all are familiar by now that
ADT
leads to accelerated BMD (bone mineral density) loss.
Y'all are familiar by now that
ADT
leads to accelerated BMD (bone mineral density) loss.
Derf4223
in
Advanced Prostate Cancer
1 year ago
Discussion about SHARE webinar: "Understanding Uterine Cancer Treatment Options" What would you like to learn more about?
For your convenience, here is the link: https://www.sharecancersupport.org/understanding-uterine-cancer-treatment-options-video/ Such a great presentation with lots information. I keep having to go back and look at it. It's one of the few webinars that even talk about my treatment option and talks
For your convenience, here is the link: https://www.sharecancersupport.org/understanding-uterine-cancer-treatment-options-video/ Such a great presentation with lots information. I keep having to go back and look at it. It's one of the few webinars that even talk about my treatment option and talks
Merma
in
SHARE Uterine Cancer Support
3 months ago
Discussion about SHARE webinar: "Understanding Uterine Cancer Treatment Options" What would you like to learn more about?
https://www.sharecancersupport.org/understanding-uterine-cancer-treatment-options-video/ Such a great presentation with lots information. I keep having to go back and look at it. It's one of the few webinars that even talk about my treatment option and talks about combined hormone therapy. How do
https://www.sharecancersupport.org/understanding-uterine-cancer-treatment-options-video/ Such a great presentation with lots information. I keep having to go back and look at it. It's one of the few webinars that even talk about my treatment option and talks about combined hormone therapy. How do
Merma
in
SHARE Uterine Cancer Support
3 months ago
Looking for suggestion of clinical trials for mCRPC
I have had SBRT (2007), Chemotherapy (2010/2011),
ADT
using Casodex/Lupron/Zytiga (2012-Current). Interested in joining trials that involve PARP inihibitors, immunotherapy, or other new/novel therapies. Can any of you suggest trials currently accepting candidates.
I have had SBRT (2007), Chemotherapy (2010/2011),
ADT
using Casodex/Lupron/Zytiga (2012-Current). Interested in joining trials that involve PARP inihibitors, immunotherapy, or other new/novel therapies. Can any of you suggest trials currently accepting candidates.
Cmdrdata
in
Advanced Prostate Cancer
1 year ago
My decision on Radiotherapy -v- Prostatectomy
I hope this story might be useful to others. I'm based in the UK and had a PSA of 12.7 from a test in June 2023. That led to an MRI in August with a PI-RADS of 5 with irregularity on the front of the prostate. I eventually had a biopsy at the end of September after 3 cancellations (this was through the
I hope this story might be useful to others. I'm based in the UK and had a PSA of 12.7 from a test in June 2023. That led to an MRI in August with a PI-RADS of 5 with irregularity on the front of the prostate. I eventually had a biopsy at the end of September after 3 cancellations (this was through the
MarkS
in
Prostate Cancer Network
3 months ago
The devil's dilemma
Between a rock and a hard place I am not sure if this topic has been discussed here before but it’s extremely frustrating to me since I don’t understand which way to go Very very interesting video. In a nut shell, the video discussion is about the introduction of NEPC and progression from HS to
Between a rock and a hard place I am not sure if this topic has been discussed here before but it’s extremely frustrating to me since I don’t understand which way to go Very very interesting video. In a nut shell, the video discussion is about the introduction of NEPC and progression from HS to
Ahk1
in
Advanced Prostate Cancer
3 months ago
Supraphysiological Androgens [SPA] Promote Tumor Suppressive Activity of the AR Through cMYC Repression and Recruitment of the DREAM Complex
In my own use of testosterone, supraphysiological androgen has not been necessary to maintain
ADT
sensitivity (for many years). However, Denmeade's focus has been on CRPC cases. “The androgen receptor (AR) pathway regulates key cell survival programs in prostate epithelium.
In my own use of testosterone, supraphysiological androgen has not been necessary to maintain
ADT
sensitivity (for many years). However, Denmeade's focus has been on CRPC cases. “The androgen receptor (AR) pathway regulates key cell survival programs in prostate epithelium.
pca2004
in
Fight Prostate Cancer
10 months ago
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