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Androgen deprivation therapy (ADT)
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ADT response and questions for MO
As he's got low volume, was healthy, lean (prior to
ADT
) and fit, and min symptoms we are wondering if he can go hard for total remission. Seems like
ADT
plus RT will knock it back for a while, until it comes back as CRPC.
As he's got low volume, was healthy, lean (prior to
ADT
) and fit, and min symptoms we are wondering if he can go hard for total remission. Seems like
ADT
plus RT will knock it back for a while, until it comes back as CRPC.
Lovecherries
in
Advanced Prostate Cancer
2 months ago
WORRIED ABOUT REOCCURRENCE???
Stopped IMRT 1 year ago and stopped
(4 mos) 9 months ago...
9/23/23 Blood Test PSA .1 --- PSA FREE undetectable and Testosterone was 98
3/4/24 Blood Test PSA .2 ----Psa Free Undetectable and Testosterone not in yet.
Stopped IMRT 1 year ago and stopped
(4 mos) 9 months ago...
9/23/23 Blood Test PSA .1 --- PSA FREE undetectable and Testosterone was 98
3/4/24 Blood Test PSA .2 ----Psa Free Undetectable and Testosterone not in yet.
JWS13
in
Advanced Prostate Cancer
1 month ago
Testosterone volatility
It was not measured again until after I started on
ADT
and it has been >7 ever since. Is there a way for me to extrapolate what it would have been in 2021 when I was DX with Gleason 9.? How Volatile are "T" numbers?
It was not measured again until after I started on
ADT
and it has been >7 ever since. Is there a way for me to extrapolate what it would have been in 2021 when I was DX with Gleason 9.? How Volatile are "T" numbers?
Scout4answers
in
Prostate Cancer Network
1 month ago
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declining psa #6
There are also some studies that show ivm to reverse
adt
castrate resistance once it starts if one chooses to continue to go that route…
There are also some studies that show ivm to reverse
adt
castrate resistance once it starts if one chooses to continue to go that route…
Nfler
in
Advanced Prostate Cancer
7 months ago
PSA doubled in last 30 days after 4 months stable since Provenge. What's next?
I have been off of all
ADT
since finishing fourth LU-177 injection five months ago and one SBRT treatment 4 months ago. After LU-177, PSA had been climbing quick until leveling off at 1.77 even as testosterone slowly returned.
I have been off of all
ADT
since finishing fourth LU-177 injection five months ago and one SBRT treatment 4 months ago. After LU-177, PSA had been climbing quick until leveling off at 1.77 even as testosterone slowly returned.
SViking
in
Advanced Prostate Cancer
2 months ago
Low T3
My endo will like me to come off
ADT
in feb once I’m back from holiday. My t3 levels have come back low and I’m not what it means. Also my gp never tests me t3.
My endo will like me to come off
ADT
in feb once I’m back from holiday. My t3 levels have come back low and I’m not what it means. Also my gp never tests me t3.
KD786
in
Thyroid UK
4 months ago
Things I Like About ADT
Eventually Darolutamide and Taxotere chemo would be added to bring that PSA down to 0.0, but in doing the obvious math the
ADT
clearly did all the heavy lifting. Bottom line, most of us are extremely fortunate to have a cancer that responds well to
ADT
.
Eventually Darolutamide and Taxotere chemo would be added to bring that PSA down to 0.0, but in doing the obvious math the
ADT
clearly did all the heavy lifting. Bottom line, most of us are extremely fortunate to have a cancer that responds well to
ADT
.
32Percenter
in
Advanced Prostate Cancer
5 months ago
Bicalutamide Vs Eligard
I'm just starting my journey which will involve
ADT
and RT. The RT is scheduled to happen in early July and
ADT
to start soon. No spread according to Pet scan. Gleason 4+4 and PSA 7.9. Absolutely no symptoms whatsoever, feeling good for a 65yo. RO doesn't seem to be in any hurry.
I'm just starting my journey which will involve
ADT
and RT. The RT is scheduled to happen in early July and
ADT
to start soon. No spread according to Pet scan. Gleason 4+4 and PSA 7.9. Absolutely no symptoms whatsoever, feeling good for a 65yo. RO doesn't seem to be in any hurry.
PJT58
in
Advanced Prostate Cancer
3 months ago
Pain post SBRT
Started on
ADT
(Firmagon and Nubeqa) in October 2023. Completed 6 cycles of docetaxel 4 wks ago. Started SBRT yesterday. My side effects thus far were all expected and I was prepared for them. Last night had severe back pain (8 out of 10) which lasted for 3-4 hours.
Started on
ADT
(Firmagon and Nubeqa) in October 2023. Completed 6 cycles of docetaxel 4 wks ago. Started SBRT yesterday. My side effects thus far were all expected and I was prepared for them. Last night had severe back pain (8 out of 10) which lasted for 3-4 hours.
Eggdoc
in
Advanced Prostate Cancer
7 days ago
PSA Gone Up
I had RP in January of 2023, started
ADT
in May of 2023 and went through 38 session of SRT between July and August. In am currently on my second six month dose of Eligard and it should be done in May of this year. In November 2023, I had my first PSA test since SRT and it was .008 ng/mL.
I had RP in January of 2023, started
ADT
in May of 2023 and went through 38 session of SRT between July and August. In am currently on my second six month dose of Eligard and it should be done in May of this year. In November 2023, I had my first PSA test since SRT and it was .008 ng/mL.
toyman79912
in
Advanced Prostate Cancer
3 months ago
Into the Great Unknown
As much as I looked forward to finishing up treatment and getting my body back from the
ADT
gremlins, I now realize that I now face a new set of unknowns and anxieties. Thanks for all of your thoughts and information that have gotten me this far.
As much as I looked forward to finishing up treatment and getting my body back from the
ADT
gremlins, I now realize that I now face a new set of unknowns and anxieties. Thanks for all of your thoughts and information that have gotten me this far.
aloha_spaceman
in
Advanced Prostate Cancer
4 months ago
Testosterone too high?
I recently had my quarterly PSA and T tests, following stopping 18 months of
ADT
(Orgovyx) in April of 2022. PSA continued to de undetectable (<0.01) and T was 761. The last quarterly T was 706.
I recently had my quarterly PSA and T tests, following stopping 18 months of
ADT
(Orgovyx) in April of 2022. PSA continued to de undetectable (<0.01) and T was 761. The last quarterly T was 706.
JPnSD
in
Advanced Prostate Cancer
3 months ago
ADT or not?
I tend to refer to this treatment as
ADT
as shorthand because to my mind they both reduce testosterone. I wonder if I’m misusing
ADT
or does it matter?
I tend to refer to this treatment as
ADT
as shorthand because to my mind they both reduce testosterone. I wonder if I’m misusing
ADT
or does it matter?
FortyWinks
in
Advanced Prostate Cancer
8 months ago
Where do I go for alternative to continuous ADT?
I want to an alternative to continuous
ADT
, whether its IADT, BAT or something else, in hopes of preventing castration resistance. I live on the East Coast of U.S. I exercise a lot each day and have cleaned up my diet.
I want to an alternative to continuous
ADT
, whether its IADT, BAT or something else, in hopes of preventing castration resistance. I live on the East Coast of U.S. I exercise a lot each day and have cleaned up my diet.
Forest1160
in
Fight Prostate Cancer
5 months ago
How to convince a GP to prescribe estradiol patches?
I've been busy with
ADT
for almost 5 years and one of the most insidious SE has always been hot flushes. I find them quite debilitating as, when they hit (and that's often), I'm briefly incapable to concentrate/perform any task.
I've been busy with
ADT
for almost 5 years and one of the most insidious SE has always been hot flushes. I find them quite debilitating as, when they hit (and that's often), I'm briefly incapable to concentrate/perform any task.
R1166
in
Advanced Prostate Cancer
28 days ago
Ugg, can we talk erections
Meaning, likely by now (more than 2mths on
ADT
) my testo has dropped very very far right? 2. Why doesnt Cialis help? 3. What is my outcome?
Meaning, likely by now (more than 2mths on
ADT
) my testo has dropped very very far right? 2. Why doesnt Cialis help? 3. What is my outcome?
Yzinger
in
Advanced Prostate Cancer
7 months ago
Dutasteride Monotherapy is effective for Newly Diagnosed PCa men not on ADT
Neither group is on
ADT
. Dutasteride monotherapy (0.5 mg/day) causes an average drop in PSA of about 50% in both Groups, and an average drop of about 20% in prostate volume. In one man, his PSA dropped from 43 to 3 (a 93% drop)!
Neither group is on
ADT
. Dutasteride monotherapy (0.5 mg/day) causes an average drop in PSA of about 50% in both Groups, and an average drop of about 20% in prostate volume. In one man, his PSA dropped from 43 to 3 (a 93% drop)!
janebob99
in
Prostate Cancer Network
1 month ago
Emotional lability and LT ADT
It's really not like me and the latest incident prompted me to look into
ADT
and emotional SE's. Bingo!
It's really not like me and the latest incident prompted me to look into
ADT
and emotional SE's. Bingo!
Derf4223
in
Advanced Prostate Cancer
7 months ago
Any Data or MO Advice Regarding Dutasteride / Finasteride At Very Early Biochemical Recurrence?
I'm wondering if early use of either of these alone may delay the necessity for
ADT
and/or delay metastasis in the long-run. I cannot find any long-term studies addressing this.
I'm wondering if early use of either of these alone may delay the necessity for
ADT
and/or delay metastasis in the long-run. I cannot find any long-term studies addressing this.
jazj
in
Advanced Prostate Cancer
3 months ago
Return of Armpit Odor - Yikes!!!
Attributable to full
ADT
(for metastatic PCa) and suppression of testosterone. (I'm on Triplet Therapy.) This morning I was surprised to notice odor for the first time since diagnosis. Due shortly for blood panel including PSA. However, I have never had a testosterone test, that I recall.
Attributable to full
ADT
(for metastatic PCa) and suppression of testosterone. (I'm on Triplet Therapy.) This morning I was surprised to notice odor for the first time since diagnosis. Due shortly for blood panel including PSA. However, I have never had a testosterone test, that I recall.
JohnInTheMiddle
in
Advanced Prostate Cancer
3 months ago
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