Fewer drugs after surgical castration? Upside? Downside?
ronton2 in Advanced Prostate Cancer 8 days ago
Is Orchiectomy a durable cure? Does one continue on some form of ADT or wait until a rise in Testosterone and PSA? I admit my ignorance, s...
Seeking comments from those who had surgical castration.
Hidden in Advanced Prostate Cancer a year ago
I am stage 4, have had radiation + Lupron for a year. oncologist plans to give lupron for total 24 months. Rather than the possibility of...
Transdermal Estrogen Versus Lupron
pjoshea13 in Advanced Prostate Cancer 2 years ago
Dr Myers latest vblog post , below.
He has previously spoken about very low dose estradiol [E2] (when on Lupron) for preserving bone healt...
easeytiger in Advanced Prostate Cancer 9 days ago
Just completed my first month of Zytiga/prednisone alongside Firmagon. My PSA at diagnosis was 55 two months ago and went quickly to 68. My ...
Melatonin & AR-V7
pjoshea13 in Advanced Prostate Cancer 9 months ago
New study below.
AR-V7 [Androgen Receptor Splice Variant-7] is an Androgen Receptor [AR] mutation that is common in CRPC [castration resistan...
Jevtana [Cabazitaxel] & Androgen Status.
pjoshea13 in Advanced Prostate Cancer 2 months ago
New Dutch study below.
Jevtana is a taxane (as is Taxotere), & was approved by the FDA for men with CRPC in 2010.
Typically, in castrate-resis...
Blair77 in Advanced Prostate Cancer 10 months ago
My husbands testosterone level is suppressed to 10 and 2.5 free. He's on Lupron and Casodex. Are these levels low enough?
Kiwidave in Advanced Prostate Cancer 5 months ago
Hi dudes.... I'm a 57 year old builder from New Zealand. I was diagnosed at 54. I had a psa of 5.6 but a very large tumor which had spread t...
T .06 is that castrate level
Kirklen1234 in Advanced Prostate Cancer a year ago
T is .06 is that castrate level
Zytia and testosterone
shortPSADT in Advanced Prostate Cancer 2 months agoPOPULAR
I've been on Zytiga three months today. A month ago my testosterone was undetectable, but the result I got yesterday was 39. (I haven't re...
Chemical vs surgical ADT.....
Jashelby in Tackle Prostate Cancer 10 months agoPOPULAR
I read so much on here about ADT with Lupron, Casodex or whatever. I had an Orchedectomy shortly after diagnosis, so when my PSA starts to ...
Is Orchidectomy right for me?
ronton2 in Advanced Prostate Cancer 9 days agoPOPULAR
I am considering surgical castration as an option to chemical treatment for PCa. I have been taking Lupron/Zytiga + prednisone for nearly ...
Father, stage 4
Novak in Advanced Prostate Cancer 7 months ago
My father is 70 years old.
Initial diagnosis: August 2014 Stage 4 PSA 700 with Bone metastasis, Gleason 4+5
Treatment: Injections of An...
Steroid receptor coactivators
pjoshea13 in Advanced Prostate Cancer 10 months ago
New paper below .
Abstract says little, but addresses a pet peeve of mine.
In the endocrine system, you get a signal intended for a gland s...
WaltL in Advanced Prostate Cancer 2 years ago
Had surgery in Jan. to remove my prostate I am 65, have low T is anyone experiencing this and what can be done.
FYI: Radiation With Antiandrogen Therapy Improves Survival in Recurrent Prostate Cancer, The New England Journal of Medicine
Attitude67 in Prostate Cancer Network a year ago
Published in Oncology
Journal Scan / Research · February 10, 2017
* This study sought to determine whether adding antiandrogen therapy to rad...
Strum on cytozan and servadio protocol from htlm of old hrpca site an old old paper but still servadio shows 50+% survival in D2 Pca @15yrs
Dan59 in Advanced Prostate Cancer a year ago
Cytoxan is often-studied as an agent for the treatment of PCa (PCRI - Sept 1997; See the writeup at the following url:
New Yorker Cancer Article is a must read
timfiskwa in Advanced Prostate Cancer 5 months ago
I just finished a good article regarding Cancer in the 9/11 issue of the \"New Yorker\" entitled \"The Invasion Equation\". It documents th...
Blair77 in Advanced Prostate Cancer 4 months ago
If I'm reading this correctly could this drug control PC indefinently?
Foods/Supplements-Vitamins: Low-Carbohydrate Diets
Typically, a low-carb diet will be high in fats. There is no obvious reason to compensate with higher levels of protein.
Ansel Keys fudged h...
I've joined The Club
Hazard in Advanced Prostate Cancer 4 months agoPOPULAR
Hi all, I've been all over the internet looking for advice on PCa and just found this site. There is some great information here and I look...
ADT or Orchiectomy
dress2544 in Advanced Prostate Cancer 11 days agoPOPULAR
I was diagnosed for advanced prostate cancer with lymph node metastases in Nov ,2015. Since the time of diagnosis I am on ADT ( lupron) inje...
Occult cancer in patients with deep-vein thrombosis [DVT].
pjoshea13 in Advanced Prostate Cancer 8 months ago
New study below .
It's a reminder that dysfunctional coagulation is an early event in cancer & after a DVT , a man should be screened for ...
Radiation as a first-line treatment
jal1954 in Advanced Prostate Cancer a year agoPOPULAR
I was diagnosed with Gleason 3+4 PCa in 2007. The two options that were recommended to me were robotic assisted radical prostatectomy or ra...
25+ Plus years but now on Lupron
jackdrum in Advanced Prostate Cancer 2 years ago
I thought I would post and see what comments I get back.
My RP was June 26, 1990, and I had a undetectable PSA for 12 years.
In my 15th ...
Coping with feelings of sexual stimulation in front of family/friends/at work...
socirul in Pelvic Pain Support Network 2 years ago
This has been the hardest and most distressing part of living with pelvic/pudendal nerve problems.
Experiencing feelings of sexual stimulatio...
Prevention better than cure.
Hidden in My Ovacome 5 years agoPOPULAR
Would it not make sense to offer all women beyond child bearing age the option of an hysterectomy. It should prevent the occurrence of OC in...
Maximum Hormone Blockade
paulofaus in Advanced Prostate Cancer a year agoPOPULAR
Hi Guys, in recent times, I've been reading up a lot about Androgen Deprivation Therapy (ADT) Intermittent ADT (IADT) and Bipolar Androgen T...
ADT failure and measuring testosterone
AlanMeyer in Advanced Prostate Cancer a year agoPOPULAR
I know at least one man who \"failed\" ADT (Lupron) and was thought to be \"castration resistant\". In fact however, when he got his testos...
STAMPEDE - Zytiga at ADT initiation. NEJM Paper.
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy
Start a Community