Hydroxychloroquine with negative ANA and blood test results

[KatieLB]

Hi I am new to all of this. Has anyone else been put on Hydroxychloroquine with negative ANA and blood test results?

[Redwine53]

Hi Katie I have negative ANA and diagnosed with scelerderma, lupus and myositis. At diagnosis I was immediately prescribed with one tablet of hydroxychloquine ( as well as prednisolone and mycophenolate) . I think the hydroxychloquine may be for the lupus, I now take two tablets of hydroxychloquine - one a.m. and another p.m. with food ( or a yoghurt) and all is fine .

[Tiggywoos in reply to Redwine53]

Hi 🍷 53 sorry to jump on the post but do you mind me asking how your Myositis and scleroderma got diagnosed ? I also have negative ana but had positive pmsl75 antibody . Thank you in advance

[Redwine53 in reply to Tiggywoos]

Hi Tiggywoos I think there had been small changes going on with my body but I was just putting it down to getting older. I was 66 at the time( now 68). Then went on a train holiday with my family and my ankles got swollen, I was tired and everything was more effort. My daughter nagged me to see my gp so I eventually went, especially as I realised I was getting a bit breathless walking up one of the hills where I live.Luckily the gp worked at a hospital rheumatology clinic once a week and ordered the right blood tests, one was my ck level which I found out was 2000. I was immediately sent to the local hospital and ten days later after a lot of tests I was diagnosed. What a shock that was.

How were you diagnosed and hope you are stable. But these things change all the time.

[Tiggywoos in reply to Redwine53]

Thank you for replying 😊. Like you I had small changes but then we went to Spain for the weekend and my face began swelling and blistering when I got home . My liver function is often high so gp admitted me to hospital with autoimmune hepatitis but hospital didn’t agree and sent me home . Over subsequent months I lost a lot of hair , started getting really run down and legs were really painful at night . Rheumatology a mess in my town (drs words ) so I went to Wales privately and was diagnosed there . Trouble is he said scleroderma needs ongoing monitoring so didn’t really work in private sector so I’ve ended up being looked after by nhs in another city ! Gosh that sounds so confusing and draining which it is ! Sadly not under control but been waiting mri results for 6 weeks . Really hope your quality of life is a bit better now x

[Tiggywoos in reply to Redwine53]

Been on hydroxy for about a year but doesn’t seem to do a great deal but who knows !

[Kels1974]

Yes I was put on it in December.

[Jmrose]

Hi Katie...mine was negative too and yes I was put on Hydroxychloraquin, mycophenolate , and nifedipine. its been helping to keep thing stable.

[KatieLB]

Thanks so much for the replies. What sort of symptoms did you experience that led to the hydroxycloroquine being prescribed even though the blood tests were negative?

[Kels1974 in reply to KatieLB]

Joint pain,dry eyes and mouth,mouth and nose sores and fatigue

[Tiggywoos]

Hi KatieLB I have raynaulds that affect hands feet nose and lips . Hair loss , rashes , mouth and nose ulcers , joint pain , headaches. I’m boring myself now lol !

I really hope you start to feel better soon . I’m only on hydroxy and it doesn’t help much 😕.

Take care x