Radiology treatment success for liver mets

[Arisgram]

Has anyone had successful radiology treatments for their liver mets? I'm researching proton therapy, Y90 and SBRT. Please let me know your experience.

All the best, Andi

[blms]

Sorry but I can't help you with this. I do have liver mets but aside from the two tumors mets seem to be spread throughout the liver. As yet, that has not been an option for me. But, I am very interested in following your procedures.

[Arisgram in reply to blms]

Can you explain "aside from the two tumors mets seem to be spread throughout the liver"? I don't understand.

[blms in reply to Arisgram]

liver shows nodular morphology with heterogeneous echogenicity and echotexture consistent with diffuse

metastatic disease and pseudocirrhosis.

Only two tumors in liver, not particuarly large but the liver is suffering across the board with cancer. Let's see what the next scan says. I no longer have any liver pain, for which I am extremely grateful.

[Arisgram in reply to blms]

Thank you. I'm certainly glad you're not in pain. The 3 tumors I have were extremely uncomfortable. What is your current treatment? I'll be sending good thoughts for effectiveness!

[blms in reply to Arisgram]

Taxol three weeks on / one off And faslodex once a month

[Mumberly in reply to blms]

Hello. My name is Kim and I came across an old message about liver Mets and your post below came up.

I also had a number of ‘less than 1cm liver lesions’ plus a couple of larger ones on my original scan a year ago.

Your comment distinguishes between liver tumours plus cancer mets throughout your liver. Can you explain the difference?

On my subsequent 2 scans, they only refer to the larger ones (just under 2cm a year ago) but they were shrinking, so I’m happy about that. I assume the smaller ones are too but the reports don’t reference them.

I’m curious to know how you are doing a year later.

Kim

[blms in reply to Mumberly]

Basically, what I said in short fashion was that my entire liver has been neurotic, hardening and not functioning well and The only cancer they tend to talk about are the tumors that they could measure which I do have to be generally a reasonable sized to see the actual mass. But they can see the rest of your liver and afternoon and everything else in the CAT scan. The doctors just don’t seem to mention all that nonsense. The fact that my liver or anyone’s liver can function when it’s mostly dead is stunning to me. But the liver is an amazing organ.

For me I’ve been staged four since 2017. And I started out with liver Mets in 2019, the cancer that was previously just pleural fluid,

So niw i’m a bit over two years it close to 2 1/2 years since it’s been spread to my liver momentum my peritoneum and some bones. I’m on my fourth line of treatment. But this was kicking my butt. So right now I’m doing pretty poorly but I see mine called is tomorrow I’ll get the results of my Liver test back to seenn B if my receptors changed.

I am really hoping to be put on the new medicine that was released about three or four weeks ago. Nobody says to be talking about it yet but it’s a study which I’ve written to other people about her septon mixed with another drug and they found out for metastatic breast cancer patients that are her manly positive and they have a very low hurt her too that they could take this drug and an extensor life and is better than any of the other on the market right now. That sounds pretty cool. Although the only thing my doctor said about it last time and it just broke and the week before and she didn’t really have a lot of information and how to get me authorized or anything else at that point what she did say was that it was not an easy chemotherapy. Course I’m taking a myself now Taxol was a breeze . I loved being a Taxol for a year the last two medication‘s have been really really rugged. Keep me informed how you’re doing. I would be fine if I wasn’t so weak and I could walk better the less medication makes your muscles really wake up my legs are just kind of a mess

[Wintervt]

Hi Andi,

I asked my oncologist about Y90. She basically told me that there is not enough data as to whether it will prolong a patient’s life but she did set up a meeting so that I can discuss it with the radiation oncologist.

Best,

Jade

[blms in reply to Wintervt]

Sometimes it is about quality of life and maybe help with any liver pain, if that is issue. But, I have no information on that.

[Arisgram in reply to Wintervt]

I had it suggested to me at MDA last year before Everolimus and Xeloda. Dr. Lim did say it was very new. Generally, the data looks promising....just not sure about MBC. I have an appointment on the 25th. I want to be prepared for the conversation as I think the Xeloda is failing. I'll be sure to let you know what he says.

[Wintervt in reply to Arisgram]

Please keep me in the loop, Andi!

[Mamacass67]

Hi there, I've had Radio Frequency Ablation to liver mets 3 times & have none in the liver now. I'm in the UK.

[queeneee in reply to Mamacass67]

Hello Mamacass67, I am in Scotland and very interested in your RF Ablation. I enquired about this with my oncologist and she said there is no protocol to do this for MBC. I am about to open up that conversation again with her - so any info you have would be useful. Where did you get it done, how large were your mets, who is your onc.. etc PM me if you feel more comfortable / thanks

[Mamacass67 in reply to queeneee]

Hello queeneee,

I asked my Onc in Maidstone to be referred to a liver specialist at Kings Hosp, London re RFA. Kings said It wasn't an option at that time as too many liver mets (looked like someone had shaken salt & pepper through my liver is how they described it) Kings suggested SIRT which you need funding for from your PCT (which I managed to get!) Went back to Kings to discuss SIRT & there had been significant reduction in mets due to chemo that Kings agreed to do RFA. They didn't get it all first time so I had it done again 6 mths later. NED for 5yrs then it came back in liver, went on Capecetabine & then had RFA again followed by another 5yrs NED.

Hope this helps.

[Arisgram in reply to Mamacass67]

Wow your liver has been through it! Congratulations! What drug therapy followed the RFA?

[Mamacass67 in reply to Arisgram]

I went on Tamoxifen for 5yrs then Letrozole for 5yrs which was strange they both stopped working almost to the day!

[queeneee in reply to Mamacass67]

Thanks very much Mamacass67. Did you have any pain or side effects or need recovery time from the RFA?

[Mamacass67 in reply to queeneee]

Yes the 1st time as they had to make an incision but the other times were carried out through the skin.

[jersey-jazz]

Memorial Sloan Kettering offers microwave ablation. I had it for a large liver tumor ablation in February.. so far ir ha been a complete success. A scan in July will be the true test.

[love2golfwell in reply to jersey-jazz]

Can you please explain microwave ablation? I have seen this term mentioned several times on this site, but am not sure what it is. Thank you!

[jersey-jazz]

Dear love2golfwell-----I am sorry to say that the way microwave ablation works is beyond my knowledge. What I can tell you from my layman's place is that it burns the cells away. and that it is the latest method used in MSKCC. My personal experience was absolutely fine as I have written elsewhere on this forum. I was under anesthesia for the procedure and when I woke up I had pain which was promptly removed by drugs. They gave me a pain medicine pump which I used with gay abandon, stayed in the hospital for two nights, went home and took only three more heavy duty narcotics for the pain and that was the end of it. I assume that the burnt out cells will be absorbed by the body. In July, I will have a scan which will reveal all.