Possible side effects of drugs

[Betbop]

Before my diagnosis in Aug of last year I already had been diagnosed with spinal stenosis and I'm finding it has gotten much worse since I've begun treatment. I'm on Ibrance Faslodex and Xgeva. My ability to walk has been comprimised drastically and I've been experiencing numb feet at times. Has anyone else had any of these problems and if so can you offer any advice?

[Selmac]

I do know that everything you mentioned are possible side effects of what you're on. The numbness should be mentioned to your Dr. It could also be neuropathy. This is what I was told while on those 3 medications.

[Betbop in reply to Selmac]

Thank you

[Betbop in reply to Selmac]

Thank you for your response

[PJBinMI]

I also had spinal stenosis before mbc, and co incidentally, have mets in that very area of the spine. I had bone mets from first cancer diagnosis, before Ibrance, and was on Femara and Zometa, then Zometa changed to Xgeva. I can tell you that when I went off Zometa, alot of the achiness of my bones got much better. I suggest talking with your onc about all this, very directly, and ask about seeing a neurosurgeon. Talk to the neurosurgeon about the condition of your spine. Stenosis can impinge on the sciatic nerve and cause numbness. I needed back surgery for a badly herniated disc and had sciatic nerve damage and my feet are numb. Physical therapy has helped alot with balance and gait and now the plan is for me to have a few weeks of PT at least a couple of times a year. My brother has diabetes and infra-red light therapy via Anodyne was very helpful to him for neuropathy in his legs and feet. My physical therapist told me that they used to do that for anybody with lower limb neuropathy and that there was always some improvement. Medicare used to cover it and does not anymore. I've looked on line and the equipment costs about $900--1000. Something else to ask your onc about.

[sweeetk in reply to PJBinMI]

I have a very similar story.

[Betbop in reply to PJBinMI]

Thank you for your response I will speak to my oncologist

[spouseM]

I get numb feet and hands intermittently on Ibrance and Letrozole. For me it does not last long. Best to you, BB

[Betbop in reply to spouseM]

Thank you for your response

[Halfpint2]

I’m on gabapentin for the numbness in my feet and hands. I can hardly hold a pen or pencil anymore. I can type like crazy but writing is nearly impossible.

[Betbop in reply to Halfpint2]

Does it give you any new side effects?

[lashinator]

I am a big fan of gabapentin. Aside from helping with the neuropathy, it eases the menopausal night sweats. I only take it before bed because it causes drowsiness. You can take up to 2900 mg safely! I started at 300, and have increased to 600. Seems to be doing the trick for now. Good luck.

[Juliandrea]

Betbop, I apologize, I just saw this post answering my question. Hope all goes well and you find relief quickly, did the drugs contribute to it getting worse or is it just over time gets worse.