Pregabalin and opioid issues?

[wantokporo]

I take 225 mg Pregabalin for PLMD. I am now having a horrific Crohn's flare and need some pain relief badly. I just took one 15 mg Oxycontin ER which I hope helps but may not be strong enough. I have Tramadol HCL 100 mg tabs, Oxycodone HCL 5 mg tablets that didn't help my PLMD but may help with pain, I pray. Are they contraindicated with the Pregabalin? Thank you.

[Madlegs1]

Opiates, in general, may be taken with Pregabalin.How all that affects your biome is another matter altogether.

I'm not expert enough in those areas to be able to help.

Hope you get some relief.

[Joolsg]

I took OxyContin and pregabalin together for 4 years with no interaction.

There are research papers that mention respiratory depression can occur if you take them together but the report only involved 49 people and those who suffered had underlying health issues and were on higher doses than are used for RLS.

medscape.com/viewarticle/92...