Oxycodone

[Shumbah]

I have been trialing 10 mg oxycodone before bed , this has offed no relief

Could this be dose related ?

[Madlegs1]

10mg would be about the highest dose advisable. That is based on Dr Buchfuhrer advice for max of 30mg per day. 10 mg at night would equate to 20 mg per day.

If 10mg is not working for you, then there is something else at play. Look at possible triggers, since they will trump the opiate.

Good luck.

[Hoffie]

I was taking 5mg before bed and another 5mg in the middle of the night and it worked pretty good for a few years. But I was becoming depressed so my doctor put my on 5mg of methadone and I feel much better. I think the methadone works better than anything I have been prescribed over the years

[Shumbah in reply to Hoffie]

Hi Hoffie

How long have you been on methadone and what form is it in?

I am pleased you are doing well it gives us hope when we feel so hopeless I am now on 20 mg of oxycodene and 1 stillnox great sleep however the afternoon pain stops me dead from 4 pm

🙂

[Hoffie in reply to Shumbah]

Hi Shumbah,

I have been on the methadone for about a month now. I take 5mg in pill form usually around 8 or 9 pm and it makes me feel drowsy enough by 10pm I go to sleep and have been sleeping 7 or 8 hours. The best sleep I have had in years. My neurologist told me to take a supplemental 5mg oxycodone for pain as needed which is only about 1 or 2 times per week. I am not sure how this will work once the weather turns cold since I usually have a lot more pain in the winter months. Best wishes, I hope you find the best medication that works for you.

[Shumbah in reply to Hoffie]

Thank you Hoffie 😊

[Mona7]

Maybe you need to break up the dose, half in morning and half at night.

Hope you find a solution.

[Shumbah]

Mine is slow release , so that is why I wondered if I should be taking it well before bed

And if a glass of wine would hurt

[involuntarydancer in reply to Shumbah]

When I started OxyContin it took 30mg to control my symptoms. I was able to reduce the dose as I got some more sleep and my serum ferritin increased but I’m not sure 10mg would control it now (I don’t use OxyContin any more because it caused profound insomnia).

Maybe you need a bit more - or to use another drug (eg gabapentin) to supplement it. Too high a dose of an opioid brings its own problems. It does seem to be that methadone works best of the opioids for many sufferers but it’s virtually impossible to access here in Ireland.

[Shumbah in reply to involuntarydancer]

Thank you lovely I tried gabapentin but severe side effects .

😞

[Lilmoma]

To involuntarydancer do u ever half a 10mg oxycodone..I looked it up an it says not to but was seeing if anyone has..

[LotteM in reply to Lilmoma]

If you have slow release oxycodon, they say you should NOT half the pills. Something to do with the outer layer instilling te slow release effect that then gets lost. However, the oxycodon SR also comes in 5mg pills - I have them. Talk to your pharmacist!

[Lilmoma in reply to LotteM]

Thank u! It was already halved so guess I won't take it

[Lilmoma in reply to Lilmoma]

It says 10 325 on it

[LotteM in reply to Lilmoma]

Ah. The 325 (mg) probably relates to the acetaminophen. If you need to take more, try to get the pure version of oxycodon SR. Otherwise you get too much and unwanted because ineffective (for RLS)

How did you get it? Did you have it prescribed by a doctor? It should.

[Lilmoma in reply to LotteM]

K thanks

[LotteM]

Shumbah, I agree with involuntarydancer. You may have to increase the dose. I take 10mg too and that works fine. I take it only in the evening and in my recent and earlier email exchange with Dr Buchfuhrer, he referred to it as a relatively low dose. From the paper on opioids for RLS it says in Table 2 that the ‘Usual effective daily dose’ is 10-30mg. If you have no daytime symptoms (they usually occur only when you have augmented on a dopamine agonist (DA) and they disappear again some time after you stop taking the DA) it means you can go as high as 30mg for the evening dose. I also take the slow release, and you need to take it 2-3hrs before bed to be effective at bedtime.

I also agree with involuntarydancer that once you have found the effective dose and it has controlled your symptoms for a while, and you feel less exhausted etc etc, you may try to reduce again slowly to find the lowest effective dose for you. The oxycodon slow release come also in 5mg pills. If you discuss with your prescribing doctor and/or pharmacist, they can give you lower-dosed pills to ‘play around’ to find this lowest effective dose.

If you can and want to change to methadone, be aware that it is stronger and that a 10mg oxycodon dose equals to about a 5mg methadone dose. See mayoclinicproceedings.org/a... for all the details.

I hope you soon find your dose. I had to increase from my initial 5 mg to the 10mg I take now.